Transient BAFF Blockade Inhibits Type 1 Diabetes Development in Nonobese Diabetic Mice by Enriching Immunoregulatory B Lymphocytes Sensitive to Deletion by Anti-CD20 Cotherapy

Genetic and Small Molecule Disruption of the AID/RAD51 Axis Similarly Protects Nonobese Diabetic Mice from Type 1 Diabetes through Expansion of Regulatory B Lymphocytes

(2017) Jeremy J. Ratiu et al.   JOURNAL OF IMMUNOLOGY

Differential Insulitic Profiles Determine the Extent of β-Cell Destruction and the Age at Onset of Type 1 Diabetes

(2016) Pia Leete et al.   DIABETES

B-Lymphocytes Expressing an Ig Specificity Recognizing the Pancreatic β-Cell Autoantigen Peripherin Are Potent Contributors to Type 1 Diabetes Development in NOD Mice

(2016) Caroline M. Leeth et al.   DIABETES

A proliferation inducing ligand (APRIL) promotes IL-10 production and regulatory functions of human B cells

(2016) Charlotte Hua et al.   JOURNAL OF AUTOIMMUNITY

Regulatory B Cells: Origin, Phenotype, and Function

(2015) Elizabeth C. Rosser et al.   IMMUNITY

The expanding family of regulatory B cells

(2015) Claudia Mauri et al.   INTERNATIONAL IMMUNOLOGY

Regulatory B cells are enriched within the IgM memory and transitional subsets in healthy donors but are deficient in chronic GVHD

(2014) A. Khoder et al.   BLOOD

Interleukin-10+Regulatory B Cells Arise Within Antigen-Experienced CD40+B Cells to Maintain Tolerance to Islet Autoantigens

(2014) Sonja Kleffel et al.   DIABETES

BAFF regulates activation of self-reactive T cells through B-cell dependent mechanisms and mediates protection in NOD mice

(2014) Eliana Mariño et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

In Vivo BLyS/BAFF Neutralization Ameliorates Islet-Directed Autoimmunity in Nonobese Diabetic Mice

(2014) G. Zekavat et al.   JOURNAL OF IMMUNOLOGY

B Lymphocyte Depletion by CD20 Monoclonal Antibody Prevents Diabetes in Nonobese Diabetic Mice despite Isotype-Specific Differences in Fc R Effector Functions

(2014) Y. Xiu et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: The Dependence of Plasma Cells and Independence of Memory B Cells on BAFF and APRIL

(2014) M. J. Benson et al.   JOURNAL OF IMMUNOLOGY

CD80 and PD-L2 define functionally distinct memory B cell subsets that are independent of antibody isotype

(2014) Griselda V Zuccarino-Catania et al.   NATURE IMMUNOLOGY

Dual B Cell Immunotherapy Is Superior to Individual Anti-CD20 Depletion or BAFF Blockade in Murine Models of Spontaneous or Accelerated Lupus

(2014) WeiYu Lin et al.   Arthritis & Rheumatology

B-Lymphocyte Depletion With Rituximab and  -Cell Function: Two-Year Results

(2013) M. D. Pescovitz et al.   DIABETES CARE

Peritoneal Cavity Regulatory B Cells (B10 Cells) Modulate IFN- +CD4+ T Cell Numbers during Colitis Development in Mice

(2013) D. Maseda et al.   JOURNAL OF IMMUNOLOGY

Efficacy and Safety of Belimumab in Patients with Rheumatoid Arthritis: A Phase II, Randomized, Double-blind, Placebo-controlled, Dose-ranging Study

(2013) W. Stohl et al.   JOURNAL OF RHEUMATOLOGY

CD39 and CD73 in immunity and inflammation

(2013) Luca Antonioli et al.   TRENDS IN MOLECULAR MEDICINE

Atacicept in patients with rheumatoid arthritis and an inadequate response to tumor necrosis factor antagonist therapy: Results of a phase II, randomized, placebo-controlled, dose-finding trial

(2011) M. C. Genovese et al.   ARTHRITIS AND RHEUMATISM

Loss of Intra-Islet CD20 Expression May Complicate Efficacy of B-Cell–Directed Type 1 Diabetes Therapies

(2011) David V. Serreze et al.   DIABETES

Efficacy and safety of belimumab in patients with active systemic lupus erythematosus: a randomised, placebo-controlled, phase 3 trial

(2011) Sandra V Navarra et al.   LANCET

Possible allelic structure of IgG2a and IgG2c in mice

(2011) Zhiping Zhang et al.   MOLECULAR IMMUNOLOGY

Advances in the Prediction and Natural History of Type 1 Diabetes

(2010) Ezio Bonifacio et al.   ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA

Cutting Edge: Hierarchy of Maturity of Murine Memory B Cell Subsets

(2010) M. M. Tomayko et al.   JOURNAL OF IMMUNOLOGY

Regulatory B Cells (B10 Cells) and Regulatory T Cells Have Independent Roles in Controlling Experimental Autoimmune Encephalomyelitis Initiation and Late-Phase Immunopathogenesis

(2010) T. Matsushita et al.   JOURNAL OF IMMUNOLOGY

Regulatory B Cells (B10 Cells) Have a Suppressive Role in Murine Lupus: CD19 and B10 Cell Deficiency Exacerbates Systemic Autoimmunity

(2010) R. Watanabe et al.   JOURNAL OF IMMUNOLOGY

Efficacy and safety of rituximab in moderately-to-severely active systemic lupus erythematosus: The randomized, double-blind, phase ii/iii systemic lupus erythematosus evaluation of rituximab trial

(2009) Joan T. Merrill et al.   ARTHRITIS AND RHEUMATISM

CD4+CD25+ T-Cells Control Autoimmunity in the Absence of B-Cells

(2009) E. Marino et al.   DIABETES

The Development and Function of Regulatory B Cells Expressing IL-10 (B10 Cells) Requires Antigen Receptor Diversity and TLR Signals

(2009) K. Yanaba et al.   JOURNAL OF IMMUNOLOGY

Rituximab, B-Lymphocyte Depletion, and Preservation of Beta-Cell Function

(2009) Mark D. Pescovitz et al.   NEW ENGLAND JOURNAL OF MEDICINE

Variability in the biological response to anti-CD20 B cell depletion in systemic lupus erythaematosus

(2008) D Albert et al.   ANNALS OF THE RHEUMATIC DISEASES

Targeting CD22 Reprograms B-Cells and Reverses Autoimmune Diabetes

(2008) P. Fiorina et al.   DIABETES

Regulatory B cells inhibit EAE initiation in mice while other B cells promote disease progression

(2008) Takashi Matsushita et al.   JOURNAL OF CLINICAL INVESTIGATION