Regulatory T Cell–Mediated Suppression of Inflammation Induced by DR3 Signaling Is Dependent on Galectin-9

Therapeutic potential of anti-CD137 (4-1BB) monoclonal antibodies

(2015) Dass S Vinay et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Galectin-9-CD44 Interaction Enhances Stability and Function of Adaptive Regulatory T Cells

(2014) Chuan Wu et al.   IMMUNITY

Galectin-9 controls the therapeutic activity of 4-1BB–targeting antibodies

(2014) Shravan Madireddi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mitigation of Experimental Allergic Encephalomyelitis by TGF-  Induced Foxp3+ Regulatory T Lymphocytes through the Induction of Anergy and Infectious Tolerance

(2014) R. K. Selvaraj et al.   JOURNAL OF IMMUNOLOGY

Immunobiology of TNFSF15 and TNFRSF25

(2013) Taylor H. Schreiber et al.   IMMUNOLOGIC RESEARCH

Self-association of the galectin-9 C-terminal domain via the opposite surface of the sugar-binding site

(2013) Yasuhiro Nonaka et al.   JOURNAL OF BIOCHEMISTRY

Cloning, Expression, and Functional Characterization of TL1A-Ig

(2013) S. Q. Khan et al.   JOURNAL OF IMMUNOLOGY

Clinical targeting of the TNF and TNFR superfamilies

(2013) Michael Croft et al.   NATURE REVIEWS DRUG DISCOVERY

Galectin-9 suppresses Th17 cell development in an IL-2-dependent but Tim-3-independent manner

(2012) Souichi Oomizu et al.   CLINICAL IMMUNOLOGY

TNFRSF25 Agonistic Antibody and Galectin-9 Combination Therapy Controls Herpes Simplex Virus-Induced Immunoinflammatory Lesions

(2012) P. B. J Reddy et al.   JOURNAL OF VIROLOGY

Galectin-9 promotes TGF-β1-dependent induction of regulatory T cells via the TGF-β/Smad signaling pathway

(2012) KUN LV et al.   Molecular Medicine Reports

Cell Surface Galectin-9 Expressing Th Cells Regulate Th17 and Foxp3+ Treg Development by Galectin-9 Secretion

(2012) Souichi Oomizu et al.   PLoS One

Galectin-9 Ameliorates Con A-Induced Hepatitis by Inducing CD4+CD25low/int Effector T-Cell Apoptosis and Increasing Regulatory T Cell Number

(2012) Kun Lv et al.   PLoS One

Tregs Expanded In Vivo by TNFRSF25 Agonists Promote Cardiac Allograft Survival

(2012) Dietlinde Wolf et al.   TRANSPLANTATION

Galectin-9 administration ameliorates CVB3 induced myocarditis by promoting the proliferation of regulatory T cells and alternatively activated Th2 cells

(2011) Kun Lv et al.   CLINICAL IMMUNOLOGY

Therapeutic potential of Galectin-9 in human disease

(2011) Valerie R. Wiersma et al.   MEDICINAL RESEARCH REVIEWS

Galectin-9 binding to cell surface protein disulfide isomerase regulates the redox environment to enhance T-cell migration and HIV entry

(2011) S. Bi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Active immunization using a single dose immunotherapeutic abates established EAE via IL-10 and regulatory T cells

(2010) Agnieszka Rynda-Apple et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Galectin-9 ameliorates acute GVH disease through the induction of T-cell apoptosis

(2010) Kazuki Sakai et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Antigenic strength controls the generation of antigen-specific IL-10-secreting T regulatory cells

(2010) Leona Gabryšová et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Therapeutic Treg expansion in mice by TNFRSF25 prevents allergic lung inflammation

(2010) Taylor H. Schreiber et al.   JOURNAL OF CLINICAL INVESTIGATION

Galectin-9 ameliorates immune complex-induced arthritis by regulating FcγR expression on macrophages

(2009) Tomohiro Arikawa et al.   CLINICAL IMMUNOLOGY

Attenuation of Th1 response through galectin-9 and T-cell Ig mucin 3 interaction inhibits autoimmune diabetes in NOD mice

(2009) Feng-Cheng Chou et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Galectin-9 expands immunosuppressive macrophages to ameliorate T-cell-mediated lung inflammation

(2009) Tomohiro Arikawa et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis

(2008) Masako Seki et al.   CLINICAL IMMUNOLOGY

The TNF-Family Receptor DR3 is Essential for Diverse T Cell-Mediated Inflammatory Diseases

(2008) Françoise Meylan et al.   IMMUNITY

Foxp3+ regulatory T cells in the control of experimental CNS autoimmune disease

(2008) Richard A. O'Connor et al.   JOURNAL OF NEUROIMMUNOLOGY