CD63-Mediated Antigen Delivery into Extracellular Vesicles via DNA Vaccination Results in Robust CD8+T Cell Responses

Neoantigen landscape dynamics during human melanoma–T cell interactions

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Targeting of cancer neoantigens with donor-derived T cell receptor repertoires

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Circulating nano-particulate TLR9 agonist scouts out tumor microenvironment to release immunogenic dead tumor cells

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Exploiting the neoantigen landscape for immunotherapy of pancreatic ductal adenocarcinoma

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Circulating Exosomes Induced by Cardiac Pressure Overload Contain Functional Angiotensin II Type 1 Receptors

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Biodistribution and delivery efficiency of unmodified tumor-derived exosomes

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Exosome mediated communication within the tumor microenvironment

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Hydroxypropyl-β-Cyclodextrin Spikes Local Inflammation That Induces Th2 Cell and T Follicular Helper Cell Responses to the Coadministered Antigen

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Extracellular vesicles in lung microenvironment and pathogenesis

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Nonagonistic Dectin-1 ligand transforms CpG into a multitask nanoparticulate TLR9 agonist

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Exosomes carrying mycobacterial antigens can protect mice againstMycobacterium tuberculosisinfection

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CD73 expression on extracellular vesicles derived from CD4+CD25+Foxp3+T cells contributes to their regulatory function

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Microvesicle-mediated Transfer of MicroRNA-150 from Monocytes to Endothelial Cells Promotes Angiogenesis

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Key roles of adjuvants in modern vaccines

(2013) Steven G Reed et al.   NATURE MEDICINE

Systemically Injected Exosomes Targeted to EGFR Deliver Antitumor MicroRNA to Breast Cancer Cells

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Active Wnt proteins are secreted on exosomes

(2012) Julia Christina Gross et al.   NATURE CELL BIOLOGY

Syndecan–syntenin–ALIX regulates the biogenesis of exosomes

(2012) Maria Francesca Baietti et al.   NATURE CELL BIOLOGY

Fluorescent labeling of nano-sized vesicles released by cells and subsequent quantitative and qualitative analysis by high-resolution flow cytometry

(2012) Els J van der Vlist et al.   Nature Protocols

Activated Human T Cells Secrete Exosomes That Participate in IL-2 Mediated Immune Response Signaling

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Harnessing DNA-induced immune responses for improving cancer vaccines

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Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes

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Intradermal delivery of vaccines: potential benefits and current challenges

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NLRP4 Negatively Regulates Autophagic Processes through an Association with Beclin1

(2011) N. Jounai et al.   JOURNAL OF IMMUNOLOGY

Human saliva, plasma and breast milk exosomes contain RNA: uptake by macrophages

(2011) Cecilia Lässer et al.   Journal of Translational Medicine

Exosome Secretion: Molecular Mechanisms and Roles in Immune Responses

(2011) Angélique Bobrie et al.   TRAFFIC

Increasing vaccine potency through exosome antigen targeting

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Dendritic Cell-Derived Exosomes for Cancer Immunotherapy: What's Next?

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Antigen-loaded exosomes alone induce Th1-type memory through a B cell-dependent mechanism

(2009) K. R. Qazi et al.   BLOOD

DNA vaccines in veterinary use

(2009) Laurel Redding et al.   Expert Review of Vaccines

Dendritic Cell-Derived Exosomes Promote Natural Killer Cell Activation and Proliferation: A Role for NKG2D Ligands and IL-15Rα

(2009) Sophie Viaud et al.   PLoS One

Targeting Tumor Antigens to Secreted Membrane Vesicles In vivo Induces Efficient Antitumor Immune Responses

(2008) I. S. Zeelenberg et al.   CANCER RESEARCH

Trafficking and function of the tetraspanin CD63

(2008) Maaike S. Pols et al.   EXPERIMENTAL CELL RESEARCH

DNA vaccines: ready for prime time?

(2008) Michele A. Kutzler et al.   NATURE REVIEWS GENETICS