Cellular function reinstitution of offspring red blood cells cloned from the sickle cell disease patient blood post CRISPR genome editing

Immunoprofiling of leukemic stem cells CD34+/CD38−/CD123+ delineate FLT3/ITD-positive clones

(2016) Adhra Al-Mawali et al.   Journal of Hematology & Oncology

CRISPR/Cas9-Mediated Correction of the Sickle Mutation in Human CD34+ cells

(2016) Megan D Hoban et al.   MOLECULAR THERAPY

Selection-free genome editing of the sickle mutation in human adult hematopoietic stem/progenitor cells

(2016) M. A. DeWitt et al.   Science Translational Medicine

Correction of the sickle cell disease mutation in human hematopoietic stem/progenitor cells

(2015) M. D. Hoban et al.   BLOOD

A unique aptamer-drug conjugate for targeted therapy of multiple myeloma

(2015) J Wen et al.   LEUKEMIA

Production of Gene-Corrected Adult Beta Globin Protein in Human Erythrocytes Differentiated from Patient iPSCs After Genome Editing of the Sickle Point Mutation

(2015) Xiaosong Huang et al.   STEM CELLS

Generation of Gene-Modified Cynomolgus Monkey via Cas9/RNA-Mediated Gene Targeting in One-Cell Embryos

(2014) Yuyu Niu et al.   CELL

One-step generation of knockout pigs by zygote injection of CRISPR/Cas system

(2014) Tang Hai et al.   CELL RESEARCH

Efficient RNA/Cas9-mediated genome editing in Xenopus tropicalis

(2014) X. Guo et al.   DEVELOPMENT

Highly Specific and Efficient CRISPR/Cas9-Catalyzed Homology-Directed Repair inDrosophila

(2014) Scott J. Gratz et al.   GENETICS

Dynamic balance of multiple myeloma clonogenic side population cell percentages controlled by environmental conditions

(2014) Jianguo Wen et al.   INTERNATIONAL JOURNAL OF CANCER

In vitro expansion of CD34+CD38− cells under stimulation with hematopoietic growth factors on AGM-S3 cells in juvenile myelomonocytic leukemia

(2014) K Sakashita et al.   LEUKEMIA

Effective gene targeting in rabbits using RNA-guided Cas9 nucleases

(2014) Dongshan Yang et al.   Journal of Molecular Cell Biology

CRISPR Is an Optimal Target for the Design of Specific PCR Assays for Salmonella enterica Serotypes Typhi and Paratyphi A

(2014) Laetitia Fabre et al.   PLoS Neglected Tropical Diseases

Generating rats with conditional alleles using CRISPR/Cas9

(2013) Yuanwu Ma et al.   CELL RESEARCH

Feasibility for a large scale mouse mutagenesis by injecting CRISPR/Cas plasmid into zygotes

(2013) Daisuke Mashiko et al.   DEVELOPMENT GROWTH & DIFFERENTIATION

β-globin gene transfer to human bone marrow for sickle cell disease

(2013) Zulema Romero et al.   JOURNAL OF CLINICAL INVESTIGATION

DNA targeting specificity of RNA-guided Cas9 nucleases

(2013) Patrick D Hsu et al.   NATURE BIOTECHNOLOGY

High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity

(2013) Vikram Pattanayak et al.   NATURE BIOTECHNOLOGY

High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

(2013) Yanfang Fu et al.   NATURE BIOTECHNOLOGY

CRISPR/Cas9 systems targeting β-globin and CCR5 genes have substantial off-target activity

(2013) Thomas J. Cradick et al.   NUCLEIC ACIDS RESEARCH

Genome engineering in Saccharomyces cerevisiae using CRISPR-Cas systems

(2013) James E. DiCarlo et al.   NUCLEIC ACIDS RESEARCH

Heritable and Precise Zebrafish Genome Editing Using a CRISPR-Cas System

(2013) Woong Y. Hwang et al.   PLoS One

RNA-Guided Human Genome Engineering via Cas9

(2013) P. Mali et al.   SCIENCE

Stem cell transplantation for treatment of sickle cell disease: Bone marrow versus cord blood transplants

(2012) L. M. Thompson et al.   AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

(2012) M. Jinek et al.   SCIENCE

Formation of mammalian erythrocytes: chromatin condensation and enucleation

(2011) Peng Ji et al.   TRENDS IN CELL BIOLOGY

Immature erythroblasts with extensive ex vivo self-renewal capacity emerge from the early mammalian fetus

(2010) S. J. England et al.   BLOOD

One hundred years of sickle cell disease

(2010) Graham R. Serjeant   BRITISH JOURNAL OF HAEMATOLOGY

Sickle-cell disease

(2010) David C Rees et al.   LANCET

BONE MARROW TRANSPLANTATION OR HYDROXYUREA FOR SICKLE CELL ANEMIA: Long-Term Effects on Semen Variables and Hormone Profiles

(2009) Aimé Kazadi Lukusa et al.   PEDIATRIC HEMATOLOGY AND ONCOLOGY