Circulating mutational portrait of cancer: manifestation of aggressive clonal events in both early and late stages

Predictive factors for EGFR -tyrosine kinase inhibitor retreatment in patients with EGFR -mutated non-small-cell lung cancer – A multicenter retrospective SEQUENCE study

(2017) Gee-Chen Chang et al.   LUNG CANCER

Osimertinib or Platinum–Pemetrexed in EGFR T790M–Positive Lung Cancer

(2017) Tony S. Mok et al.   NEW ENGLAND JOURNAL OF MEDICINE

Analysis of DNA methylation in single circulating tumor cells

(2017) C F Pixberg et al.   ONCOGENE

Blood-based biomarkers for diagnosis, prognosis and treatment of colorectal cancer

(2016) Ebru E. Yörüker et al.   CLINICA CHIMICA ACTA

Detection of Therapeutically Targetable Driver and Resistance Mutations in Lung Cancer Patients by Next-Generation Sequencing of Cell-Free Circulating Tumor DNA

(2016) J. C. Thompson et al.   CLINICAL CANCER RESEARCH

A Prospective Evaluation of Circulating Tumor Cells and Cell-Free DNA in EGFR-Mutant Non-Small Cell Lung Cancer Patients Treated with Erlotinib on a Phase II Trial

(2016) M. Yanagita et al.   CLINICAL CANCER RESEARCH

Mutation Analysis of Cell-Free DNA and Single Circulating Tumor Cells in Metastatic Breast Cancer Patients with High Circulating Tumor Cell Counts

(2016) Jacqueline A. Shaw et al.   CLINICAL CANCER RESEARCH

Circulating Cell-Free Tumor DNA Analysis of 50 Genes by Next-Generation Sequencing in the Prospective MOSCATO Trial

(2016) C. Jovelet et al.   CLINICAL CANCER RESEARCH

Synthetic Lethal Targeting of ARID1A -Mutant Ovarian Clear Cell Tumors with Dasatinib

(2016) Rowan E. Miller et al.   MOLECULAR CANCER THERAPEUTICS

Molecular profiling of single circulating tumor cells from lung cancer patients

(2016) Seung-min Park et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cancers Screening in an Asymptomatic Population by Using Multiple Tumour Markers

(2016) Hsin-Yao Wang et al.   PLoS One

Circulating DNA and Survival in Solid Tumors

(2015) A. Ocana et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Diagnostic Accuracy of Noninvasive Genotyping of EGFR in Lung Cancer Patients by Deep Sequencing of Plasma Cell-Free DNA

(2015) J. Uchida et al.   CLINICAL CHEMISTRY

Sampling circulating tumor cells for clinical benefits: how frequent?

(2015) Sai Mun Leong et al.   Journal of Hematology & Oncology

Non-invasive approaches to monitor EGFR-TKI treatment in non-small-cell lung cancer

(2015) Wei Sun et al.   Journal of Hematology & Oncology

Role of circulating-tumor DNA analysis in non-small cell lung cancer

(2015) Tao Jiang et al.   LUNG CANCER

Cell-free circulating tumour DNA as a liquid biopsy in breast cancer

(2015) Leticia De Mattos-Arruda et al.   Molecular Oncology

Mutational landscape of gastric adenocarcinoma in Chinese: Implications for prognosis and therapy

(2015) Kexin Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glycosylation-Based Serum Biomarkers for Cancer Diagnostics and Prognostics

(2015) Alan Kirwan et al.   Biomed Research International

Analytical and Clinical Validation of a Digital Sequencing Panel for Quantitative, Highly Accurate Evaluation of Cell-Free Circulating Tumor DNA

(2015) Richard B. Lanman et al.   PLoS One

Novel Methylated Biomarkers and a Robust Assay to Detect Circulating Tumor DNA in Metastatic Breast Cancer

(2014) Mary Jo Fackler et al.   CANCER RESEARCH

Comprehensive molecular profiling of lung adenocarcinoma

(2014) Eric A. Collisson et al.   NATURE

Increased lung cancer risk in patients with interstitial lung disease and elevated CEA and CA125 serum tumour markers

(2014) Huaping Dai et al.   RESPIROLOGY

Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies

(2014) C. Bettegowda et al.   Science Translational Medicine

SciClone: Inferring Clonal Architecture and Tracking the Spatial and Temporal Patterns of Tumor Evolution

(2014) Christopher A. Miller et al.   PLoS Computational Biology

Combined use of AFP, CEA, CA125 and CAl9-9 improves the sensitivity for the diagnosis of gastric cancer

(2013) Chao-Zhu He et al.   BMC GASTROENTEROLOGY

Monitoring tumor-derived cell-free DNA in patients with solid tumors: Clinical perspectives and research opportunities

(2013) Angela Esposito et al.   CANCER TREATMENT REVIEWS

Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing

(2013) Garrett M Frampton et al.   NATURE BIOTECHNOLOGY

Analysis of Circulating Tumor DNA to Monitor Metastatic Breast Cancer

(2013) Sarah-Jane Dawson et al.   NEW ENGLAND JOURNAL OF MEDICINE

Causal inference for Mann-Whitney-Wilcoxon rank sum and other nonparametric statistics

(2013) P. Wu et al.   STATISTICS IN MEDICINE

A Framework for Evaluating Biomarkers for Early Detection: Validation of Biomarker Panels for Ovarian Cancer

(2011) C. S. Zhu et al.   Cancer Prevention Research

Association of BRCA1 and BRCA2 Mutations With Survival, Chemotherapy Sensitivity, and Gene Mutator Phenotype in Patients With Ovarian Cancer

(2011) Da Yang et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Kinase-Dead BRAF and Oncogenic RAS Cooperate to Drive Tumor Progression through CRAF

(2010) Sonja J. Heidorn et al.   CELL

Association of core-binding factor β with the malignant phenotype of prostate and ovarian cancer cells

(2010) J. Nathan Davis et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Ligand-Dependent Platelet-Derived Growth Factor Receptor (PDGFR)-  Activation Sensitizes Rare Lung Cancer and Sarcoma Cells to PDGFR Kinase Inhibitors

(2009) U. McDermott et al.   CANCER RESEARCH

First-Line Gefitinib in Patients With Advanced Non–Small-Cell Lung Cancer Harboring SomaticEGFRMutations

(2008) Lecia V. Sequist et al.   JOURNAL OF CLINICAL ONCOLOGY

Circulating mutant DNA to assess tumor dynamics

(2008) Frank Diehl et al.   NATURE MEDICINE