Mechanism of sodium channel block by local anesthetics, antiarrhythmics, and anticonvulsants
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Mechanism of sodium channel block by local anesthetics, antiarrhythmics, and anticonvulsants
Authors
Keywords
-
Journal
JOURNAL OF GENERAL PHYSIOLOGY
Volume 149, Issue 4, Pages 465-481
Publisher
Rockefeller University Press
Online
2017-03-03
DOI
10.1085/jgp.201611668
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Molecular basis of ion permeability in a voltage‐gated sodium channel
- (2016) Claire E Naylor et al. EMBO JOURNAL
- Modeling interactions between blocking and permeant cations in the NavMs channel
- (2016) Vyacheslav S. Korkosh et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Structure of the voltage-gated calcium channel Cav1.1 at 3.6 Å resolution
- (2016) Jianping Wu et al. NATURE
- Structure of the voltage-gated calcium channel Cav1.1 complex
- (2015) J. Wu et al. SCIENCE
- State-dependent inter-repeat contacts of exceptionally conserved asparagines in the inner helices of sodium and calcium channels
- (2014) Denis B. Tikhonov et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Local anesthetic and antiepileptic drug access and binding to a bacterial voltage-gated sodium channel
- (2014) C. Boiteux et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Prokaryotic NavMs channel as a structural and functional model for eukaryotic sodium channel antagonism
- (2014) C. Bagneris et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural basis for Ca2+ selectivity of a voltage-gated calcium channel
- (2013) Lin Tang et al. NATURE
- Ligand action on sodium, potassium, and calcium channels: role of permeant ions
- (2013) Boris S. Zhorov et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Voltage-gated sodium channels at 60: structure, function and pathophysiology
- (2012) William A. Catterall JOURNAL OF PHYSIOLOGY-LONDON
- Crystal structure of an orthologue of the NaChBac voltage-gated sodium channel
- (2012) Xu Zhang et al. NATURE
- Bisphenol A Binds to the Local Anesthetic Receptor Site to Block the Human Cardiac Sodium Channel
- (2012) Andrias O. O’Reilly et al. PLoS One
- Structural modelling and mutant cycle analysis predict pharmacoresponsiveness of a Nav1.7 mutant channel
- (2012) Yang Yang et al. Nature Communications
- The Enigmatic Drug Binding Site for Sodium Channel Inhibitors
- (2012) Arpad Mike et al. Current Molecular Pharmacology
- The crystal structure of a voltage-gated sodium channel
- (2011) Jian Payandeh et al. NATURE
- Molecular basis for class Ib anti-arrhythmic inhibition of cardiac sodium channels
- (2011) Stephan A. Pless et al. Nature Communications
- Docking flexible ligands in proteins with a solvent exposure- and distance-dependent dielectric function
- (2010) Daniel P. Garden et al. JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN
- Molecular Model of Anticonvulsant Drug Binding to the Voltage-Gated Sodium Channel Inner Pore
- (2010) G. M. Lipkind et al. MOLECULAR PHARMACOLOGY
- MolProbity: all-atom structure validation for macromolecular crystallography
- (2009) Vincent B. Chen et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Structural Determinants of Drugs Acting on the Nav1.8 Channel
- (2009) Liam E. Browne et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Novel Molecular Determinants in the Pore Region of Sodium Channels Regulate Local Anesthetic Binding
- (2009) T. Yamagishi et al. MOLECULAR PHARMACOLOGY
- Access and Binding of Local Anesthetics in the Closed Sodium Channel
- (2008) I. Bruhova et al. MOLECULAR PHARMACOLOGY
- Electrostatic Contributions of Aromatic Residues in the Local Anesthetic Receptor of Voltage-Gated Sodium Channels
- (2007) Christopher A. Ahern et al. CIRCULATION RESEARCH
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now