Fusion pores and their control of neurotransmitter and hormone release

Calculating Transition Energy Barriers and Characterizing Activation States for Steps of Fusion

(2016) Rolf J. Ryham et al.   BIOPHYSICAL JOURNAL

Hemi-fused structure mediates and controls fusion and fission in live cells

(2016) Wei-Dong Zhao et al.   NATURE

Nanodisc-cell fusion: control of fusion pore nucleation and lifetimes by SNARE protein transmembrane domains

(2016) Zhenyong Wu et al.   Scientific Reports

The Hydrophobic Effect in Solute Partitioning and Interfacial Tension

(2016) Meyer B. Jackson   Scientific Reports

v-SNARE transmembrane domains function as catalysts for vesicle fusion

(2016) Madhurima Dhara et al.   eLife

Synaptobrevin Transmembrane Domain Influences Exocytosis by Perturbing Vesicle Membrane Curvature

(2015) Che-Wei Chang et al.   BIOPHYSICAL JOURNAL

Membrane tension and membrane fusion

(2015) Michael M Kozlov et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Vacuolar SNARE Protein Transmembrane Domains Serve as Nonspecific Membrane Anchors with Unequal Roles in Lipid Mixing

(2015) Michel Pieren et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipid-anchored Synaptobrevin Provides Little or No Support for Exocytosis or Liposome Fusion

(2015) Che-Wei Chang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Structural Role for the Synaptobrevin 2 Transmembrane Domain in Dense-Core Vesicle Fusion Pores

(2015) C.-W. Chang et al.   JOURNAL OF NEUROSCIENCE

Exocytotic fusion pores are composed of both lipids and proteins

(2015) Huan Bao et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Exocytotic fusion pores are composed of both lipids and proteins

(2015) Huan Bao et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Architecture of the Synaptophysin/Synaptobrevin Complex: Structural Evidence for an Entropic Clustering Function at the Synapse

(2015) Daniel J. Adams et al.   Scientific Reports

Lumenal Protein within Secretory Granules Affects Fusion Pore Expansion

(2014) Annita Ngatchou Weiss et al.   BIOPHYSICAL JOURNAL

Cdc42 controls the dilation of the exocytotic fusion pore by regulating membrane tension

(2014) Marine Bretou et al.   MOLECULAR BIOLOGY OF THE CELL

A Comparison of Coarse-Grained and Continuum Models for Membrane Bending in Lipid Bilayer Fusion Pores

(2013) Jejoong Yoo et al.   BIOPHYSICAL JOURNAL

Amperometric Measurements at Cells Support a Role for Dynamin in the Dilation of the Fusion Pore during Exocytosis

(2013) Raphaël Trouillon et al.   CHEMPHYSCHEM

Lipid-Anchored SNAREs Lacking Transmembrane Regions Fully Support Membrane Fusion during Neurotransmitter Release

(2013) Peng Zhou et al.   NEURON

Teardrop shapes minimize bending energy of fusion pores connecting planar bilayers

(2013) Rolf J. Ryham et al.   PHYSICAL REVIEW E

Dynamin-2 Regulates Fusion Pore Expansion and Quantal Release through a Mechanism that Involves Actin Dynamics in Neuroendocrine Chromaffin Cells

(2013) Arlek M. González-Jamett et al.   PLoS One

Fusion pore formation and expansion induced by Ca2+and synaptotagmin 1

(2013) Ying Lai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Coarse-Grain Simulations Reveal Movement of the Synaptobrevin C-Terminus in Response to Piconewton Forces

(2012) Manfred Lindau et al.   BIOPHYSICAL JOURNAL

Activity-Dependent Fusion Pore Expansion Regulated by a Calcineurin-Dependent Dynamin-Syndapin Pathway in Mouse Adrenal Chromaffin Cells

(2012) P. Samasilp et al.   JOURNAL OF NEUROSCIENCE

Membrane-Proximal Tryptophans of Synaptobrevin II Stabilize Priming of Secretory Vesicles

(2012) M. Borisovska et al.   JOURNAL OF NEUROSCIENCE

SNARE Proteins: One to Fuse and Three to Keep the Nascent Fusion Pore Open

(2012) L. Shi et al.   SCIENCE

Amperometric post spike feet reveal most exocytosis is via extended kiss-and-run fusion

(2012) Lisa J. Mellander et al.   Scientific Reports

A new role for the dynamin GTPase in the regulation of fusion pore expansion

(2011) Arun Anantharam et al.   MOLECULAR BIOLOGY OF THE CELL

Synaptophysin Regulates the Kinetics of Synaptic Vesicle Endocytosis in Central Neurons

(2011) Sung E. Kwon et al.   NEURON

Two synaptobrevin molecules are sufficient for vesicle fusion in central nervous system synapses

(2011) R. Sinha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A lipid-anchored SNARE supports membrane fusion

(2011) H. Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Docking and Fast Fusion of Synaptobrevin Vesicles Depends on the Lipid Compositions of the Vesicle and the Acceptor SNARE Complex-Containing Target Membrane

(2010) Marta K. Domanska et al.   BIOPHYSICAL JOURNAL

Membrane Bending Energy and Fusion Pore Kinetics in Ca2+-Triggered Exocytosis

(2010) Zhen Zhang et al.   BIOPHYSICAL JOURNAL

Synaptotagmin IV Modulation of Vesicle Size and Fusion Pores in PC12 Cells

(2010) Zhenjie Zhang et al.   BIOPHYSICAL JOURNAL

Quantitative analysis of the native presynaptic cytomatrix by cryoelectron tomography

(2010) Rubén Fernández-Busnadiego et al.   JOURNAL OF CELL BIOLOGY

SNARE Complex Zipping as a Driving Force in the Dilation of Proteinaceous Fusion Pores

(2010) Meyer B. Jackson   JOURNAL OF MEMBRANE BIOLOGY

SNARE Force Synchronizes Synaptic Vesicle Fusion and Controls the Kinetics of Quantal Synaptic Transmission

(2010) R. E. Guzman et al.   JOURNAL OF NEUROSCIENCE

Influence of Cholesterol on Catecholamine Release from the Fusion Pore of Large Dense Core Chromaffin Granules

(2010) N. Wang et al.   JOURNAL OF NEUROSCIENCE

The Association of Dynamin with Synaptophysin Regulates Quantal Size and Duration of Exocytotic Events in Chromaffin Cells

(2010) A. M. Gonzalez-Jamett et al.   JOURNAL OF NEUROSCIENCE

Regulation of Exocytosis and Fusion Pores by Synaptotagmin-Effector Interactions

(2010) Zhen Zhang et al.   MOLECULAR BIOLOGY OF THE CELL

One SNARE complex is sufficient for membrane fusion

(2010) Geert van den Bogaart et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Role of the synaptobrevin C terminus in fusion pore formation

(2010) A. N. Ngatchou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fast Vesicle Fusion in Living Cells Requires at Least Three SNARE Complexes

(2010) R. Mohrmann et al.   SCIENCE

The Fusion Pore and Vesicle Cargo Discharge Modulation

(2009) Nina Vardjan et al.   Annals of the New York Academy of Sciences

Conflicting Views on the Membrane Fusion Machinery and the Fusion Pore

(2009) Jakob B. Sørensen   Annual Review of Cell and Developmental Biology

Minimum Membrane Bending Energies of Fusion Pores

(2009) Meyer B. Jackson   JOURNAL OF MEMBRANE BIOLOGY

Vesicular release mode shapes the postsynaptic response at hippocampal synapses

(2009) David A. Richards   JOURNAL OF PHYSIOLOGY-LONDON

Phosphatidylserine Regulation of Ca2+-triggered Exocytosis and Fusion Pores in PC12 Cells

(2009) Zhen Zhang et al.   MOLECULAR BIOLOGY OF THE CELL

Dynamin I plays dual roles in the activity-dependent shift in exocytic mode in mouse adrenal chromaffin cells

(2008) Tiberiu Fulop et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

The Gaussian Curvature Elastic Energy of Intermediates in Membrane Fusion

(2008) David P. Siegel   BIOPHYSICAL JOURNAL

Myosin II Contributes to Fusion Pore Expansion during Exocytosis

(2008) Patricia Ñeco et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Temperature Dependence of Fusion Kinetics and Fusion Pores in Ca2+-triggered Exocytosis from PC12 Cells

(2008) Zhen Zhang et al.   JOURNAL OF GENERAL PHYSIOLOGY

Synaptotagmin-1 Utilizes Membrane Bending and SNARE Binding to Drive Fusion Pore Expansion

(2008) Kara L. Lynch et al.   MOLECULAR BIOLOGY OF THE CELL

The fusion pores of Ca2+-triggered exocytosis

(2008) Meyer B Jackson et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure of transmembrane pore induced by Bax-derived peptide: Evidence for lipidic pores

(2008) S. Qian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role of the C terminus of the SNARE protein SNAP-25 in fusion pore opening and a model for fusion pore mechanics

(2008) Q. Fang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Munc-18-1 Regulates the Initial Release Rate of Exocytosis

(2007) Jeff W. Barclay   BIOPHYSICAL JOURNAL

SNARE-catalyzed Fusion Events Are Regulated by Syntaxin1A–Lipid Interactions

(2007) Alice D. Lam et al.   MOLECULAR BIOLOGY OF THE CELL