Promising therapeutic efficacy of a novel reduced expression in immortalized cells/dickkopf-3 expressing adenoviral vector for hepatocellular carcinoma

Novel REIC/Dkk-3-encoding adenoviral vector as a promising therapeutic agent for pancreatic cancer

(2016) H Sawahara et al.   CANCER GENE THERAPY

Adenovirus vector carrying REIC/DKK-3 gene: neoadjuvant intraprostatic injection for high-risk localized prostate cancer undergoing radical prostatectomy

(2016) H Kumon et al.   CANCER GENE THERAPY

The induction of antigen-specific CTL by in situ Ad-REIC gene therapy

(2016) Y Ariyoshi et al.   GENE THERAPY

Combined therapy with oncolytic adenoviruses encoding TRAIL and IL-12 genes markedly suppressed human hepatocellular carcinoma both in vitro and in an orthotopic transplanted mouse model

(2016) Adel Galal El-Shemi et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Feasibility of Neoadjuvant Ad-REIC Gene Therapy in Patients with High-Risk Localized Prostate Cancer Undergoing Radical Prostatectomy

(2015) Hiromi Kumon et al.   CTS-Clinical and Translational Science

The cysteine-rich core domain of REIC/Dkk-3 is critical for its effect on monocyte differentiation and tumor regression

(2015) RIE KINOSHITA et al.   ONCOLOGY REPORTS

Surveillance, Diagnosis, Treatment, and Outcome of Liver Cancer in Japan

(2015) Masatoshi Kudo   Liver Cancer

A novel gene expression system strongly enhances the anticancer effects of a REIC/Dkk-3-encoding adenoviral vector

(2014) MASAMI WATANABE et al.   ONCOLOGY REPORTS

Potential of adenovirus-mediated REIC/Dkk-3 gene therapy for use in the treatment of pancreatic cancer

(2013) Daisuke Uchida et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Association of changes in the gene expression profile of blood cells with the local tumor inflammatory response in a murine tumor model

(2012) Yoshio Sakai et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

REIC/Dkk-3-encoding adenoviral vector as a potentially effective therapeutic agent for bladder cancer

(2012) TAKESHI HIRATA et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Hepatocellular Carcinoma

(2011) Hashem B. El-Serag   NEW ENGLAND JOURNAL OF MEDICINE

A phase I clinical trial of thymidine kinase-based gene therapy in advanced hepatocellular carcinoma

(2010) B Sangro et al.   CANCER GENE THERAPY

Immunological aspects of REIC/Dkk-3 in monocyte differentiation and tumor regression

(2009) Watanabe   INTERNATIONAL JOURNAL OF ONCOLOGY

Overexpression ofREIC/Dkk-3in Normal Fibroblasts Suppresses Tumor Growth via Induction of Interleukin-7

(2009) Masakiyo Sakaguchi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Clinical study of recombinant adenovirus-p53 combined with fractionated stereotactic radiotherapy for hepatocellular carcinoma

(2009) Zhi-xiang Yang et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

REIC/Dkk-3 overexpression downregulates P-glycoprotein in multidrug-resistant MCF7/ADR cells and induces apoptosis in breast cancer

(2008) K Kawasaki et al.   CANCER GENE THERAPY

Down-regulation of Inhibition of Differentiation-1 via Activation of Activating Transcription Factor 3 and Smad Regulates REIC/Dickkopf-3-Induced Apoptosis

(2008) Y. Kashiwakura et al.   CANCER RESEARCH

Diagnosis and Treatment of Hepatocellular Carcinoma

(2008) Hashem B. El-Serag et al.   GASTROENTEROLOGY

REIC/Dkk-3 induces cell death in human malignant glioma

(2008) Yoshifumi Mizobuchi et al.   NEURO-ONCOLOGY