Self-reactive VH4-34–expressing IgG B cells recognize commensal bacteria

Scarcity of autoreactive human blood IgA+memory B cells

(2016) Julie Prigent et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Clonal redemption of autoantibodies by somatic hypermutation away from self-reactivity during human immunization

(2016) Joanne H. Reed et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Circulating Human CD27−IgA+Memory B Cells Recognize Bacteria with Polyreactive Igs

(2015) Magdalena A. Berkowska et al.   JOURNAL OF IMMUNOLOGY

Diversity, cellular origin and autoreactivity of antibody-secreting cell population expansions in acute systemic lupus erythematosus

(2015) Christopher M Tipton et al.   NATURE IMMUNOLOGY

Survival of human lymphoma cells requires B-cell receptor engagement by self-antigens

(2015) Ryan M. Young et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IRAK-4 and MyD88 deficiencies impair IgM responses against T-independent bacterial antigens

(2014) P. J. Maglione et al.   BLOOD

B Cell–Intrinsic TLR7 Signaling Is Essential for the Development of Spontaneous Germinal Centers

(2014) Chetna Soni et al.   JOURNAL OF IMMUNOLOGY

The SLE Transcriptome Exhibits Evidence of Chronic Endotoxin Exposure and Has Widespread Dysregulation of Non-Coding and Coding RNAs

(2014) Lihua Shi et al.   PLoS One

Redemption of autoantibodies on anergic B cells by variable-region glycosylation and mutation away from self-reactivity

(2014) Z. Sabouri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intestinal Dysbiosis Associated with Systemic Lupus Erythematosus

(2014) A. Hevia et al.   mBio

CVID-associated TACI mutations affect autoreactive B cell selection and activation

(2013) Neil Romberg et al.   JOURNAL OF CLINICAL INVESTIGATION

Germinal Centers

(2012) Gabriel D. Victora et al.   Annual Review of Immunology

IgM+IgD+CD27+ B cells are markedly reduced in IRAK-4-, MyD88-, and TIRAP- but not UNC-93B-deficient patients

(2012) S. Weller et al.   BLOOD

B Cell-Intrinsic MyD88 Signaling Prevents the Lethal Dissemination of Commensal Bacteria during Colonic Damage

(2012) Donna Kirkland et al.   IMMUNITY

BCR-signalling synergizes with TLR-signalling for induction of AID and immunoglobulin class-switching through the non-canonical NF-κB pathway

(2012) Egest J. Pone et al.   Nature Communications

Human TLRs and IL-1Rs in Host Defense: Natural Insights from Evolutionary, Epidemiological, and Clinical Genetics

(2011) Jean-Laurent Casanova et al.   Annual Review of Immunology

Human memory B cells originate from three distinct germinal center-dependent and -independent maturation pathways

(2011) M. A. Berkowska et al.   BLOOD

Selective Utilization of Toll-like Receptor and MyD88 Signaling in B Cells for Enhancement of the Antiviral Germinal Center Response

(2011) Baidong Hou et al.   IMMUNITY

The majority of intestinal IgA+ and IgG+ plasmablasts in the human gut are antigen-specific

(2011) Julia Benckert et al.   JOURNAL OF CLINICAL INVESTIGATION

The PTPN22 allele encoding an R620W variant interferes with the removal of developing autoreactive B cells in humans

(2011) Laurence Menard et al.   JOURNAL OF CLINICAL INVESTIGATION

Broadly cross-reactive antibodies dominate the human B cell response against 2009 pandemic H1N1 influenza virus infection

(2011) Jens Wrammert et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Programming the magnitude and persistence of antibody responses with innate immunity

(2011) Sudhir Pai Kasturi et al.   NATURE

Differential regulation of self-reactivity discriminates between IgG+ human circulating memory B cells and bone marrow plasma cells

(2011) J. F. Scheid et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation

(2010) Hugo Mouquet et al.   NATURE

The transmembrane activator TACI triggers immunoglobulin class switching by activating B cells through the adaptor MyD88

(2010) Bing He et al.   NATURE IMMUNOLOGY

Control systems and decision making for antibody production

(2010) Christopher C Goodnow et al.   NATURE IMMUNOLOGY

Secretory IgA-Mediated Neutralization of Shigella flexneri Prevents Intestinal Tissue Destruction by Down-Regulating Inflammatory Circuits

(2009) S. Boullier et al.   JOURNAL OF IMMUNOLOGY

Innate and Adaptive Immunity Cooperate Flexibly to Maintain Host-Microbiota Mutualism

(2009) E. Slack et al.   SCIENCE

IRAK-4- and MyD88-Dependent Pathways Are Essential for the Removal of Developing Autoreactive B Cells in Humans

(2008) Isabelle Isnardi et al.   IMMUNITY

Pyogenic Bacterial Infections in Humans with MyD88 Deficiency

(2008) H. von Bernuth et al.   SCIENCE

Anti-D and anti-i activities are inseparable in V4-34-encoded monoclonal anti-D: the same framework 1 residues are required for both reactivities

(2008) Susan J. Thorpe et al.   TRANSFUSION

Efficient generation of monoclonal antibodies from single human B cells by single cell RT-PCR and expression vector cloning

(2007) Thomas Tiller et al.   JOURNAL OF IMMUNOLOGICAL METHODS