30 YEARS OF THE MINERALOCORTICOID RECEPTOR: Mineralocorticoid receptor null mice: informing cell-type-specific roles

Apparent mineralocorticoid excess

(2017) John W. Funder   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Mineralocorticoid Receptor Deficiency in Macrophages Inhibits Neointimal Hyperplasia and Suppresses Macrophage Inflammation Through SGK1-AP1/NF-κB PathwaysSignificance

(2016) Jian-Yong Sun et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Endothelial Mineralocorticoid Receptor Mediates Diet-Induced Aortic Stiffness in FemalesNovelty and Significance

(2016) Guanghong Jia et al.   CIRCULATION RESEARCH

Mineralocorticoid receptor antagonists—pharmacodynamics and pharmacokinetic differences

(2016) Jun Yang et al.   CURRENT OPINION IN PHARMACOLOGY

Cardiac Tissue Injury and Remodeling Is Dependent Upon MR Regulation of Activation Pathways in Cardiac Tissue Macrophages

(2016) Jimmy Z. Shen et al.   ENDOCRINOLOGY

Epidermal Mineralocorticoid Receptor Plays Beneficial and Adverse Effects in Skin and Mediates Glucocorticoid Responses

(2016) Julia Boix et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Deletion of mineralocorticoid receptors in smooth muscle cells blunts renal vascular resistance following acute cyclosporine administration

(2016) Cristian A. Amador et al.   KIDNEY INTERNATIONAL

Adult nephron-specific MR-deficient mice develop a severe renal PHA-1 phenotype

(2016) Jérémie Canonica et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Aldosterone-Mediated Renal Sodium Transport Requires Intact Mineralocorticoid Receptor DNA-Binding in the Mouse

(2015) Timothy J. Cole et al.   ENDOCRINOLOGY

Cardiomyocyte Mineralocorticoid Receptor Activation Impairs Acute Cardiac Functional Recovery After Ischemic InsultNovelty and Significance

(2015) Laura A. Bienvenu et al.   HYPERTENSION

Endothelial Mineralocorticoid Receptors Differentially Contribute to Coronary and Mesenteric Vascular Function Without Modulating Blood PressureNovelty and Significance

(2015) Katelee Barrett Mueller et al.   HYPERTENSION

Finerenone Impedes Aldosterone-dependent Nuclear Import of the Mineralocorticoid Receptor and Prevents Genomic Recruitment of Steroid Receptor Coactivator-1

(2015) Larbi Amazit et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Direct and Indirect Mineralocorticoid Effects Determine Distal Salt Transport

(2015) A. S. Terker et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Inducible Knock-Down of the Mineralocorticoid Receptor in Mice Disturbs Regulation of the Renin-Angiotensin-Aldosterone System and Attenuates Heart Failure Induced by Pressure Overload

(2015) Elena Montes-Cobos et al.   PLoS One

Identification and characterization of a ligand-selective mineralocorticoid receptor coactivator

(2014) Fraser M. Rogerson et al.   FASEB JOURNAL

Endothelial Cell Mineralocorticoid Receptors Regulate Deoxycorticosterone/Salt-Mediated Cardiac Remodeling and Vascular Reactivity But Not Blood Pressure

(2014) Amanda J. Rickard et al.   HYPERTENSION

Aldosterone Promotes Vascular Remodeling by Direct Effects on Smooth Muscle Cell Mineralocorticoid Receptors

(2013) Dafina Pruthi et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Endothelial mineralocorticoid receptor activation mediates endothelial dysfunction in diet-induced obesity

(2013) Nicola Schäfer et al.   EUROPEAN HEART JOURNAL

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

Myeloid Mineralocorticoid Receptor During Experimental Ischemic Stroke: Effects of Model and Sex

(2013) Ryan A. Frieler et al.   Journal of the American Heart Association

Macrophage Mineralocorticoid Receptor Signaling Plays a Key Role in Aldosterone-Independent Cardiac Fibrosis

(2012) Laura A. Bienvenu et al.   ENDOCRINOLOGY

Cardiomyocyte Mineralocorticoid Receptors Are Essential for Deoxycorticosterone/Salt-Mediated Inflammation and Cardiac Fibrosis

(2012) Amanda J. Rickard et al.   HYPERTENSION

Direct regulation of blood pressure by smooth muscle cell mineralocorticoid receptors

(2012) Amy McCurley et al.   NATURE MEDICINE

Deletion of Cardiomyocyte Mineralocorticoid Receptor Ameliorates Adverse Remodeling After Myocardial Infarction

(2011) Daniela Fraccarollo et al.   CIRCULATION

Aldosterone Postnatally, but not at Birth, Is Required for Optimal Induction of Renal Mineralocorticoid Receptor Expression and Sodium Reabsorption

(2011) Laetitia Martinerie et al.   ENDOCRINOLOGY

Ablation of Mineralocorticoid Receptors in Myocytes But Not in Fibroblasts Preserves Cardiac Function

(2011) Achim Lother et al.   HYPERTENSION

Minireview: Aldosterone and Mineralocorticoid Receptors: Past, Present, and Future

(2010) John W. Funder   ENDOCRINOLOGY

Myeloid mineralocorticoid receptor controls macrophage polarization and cardiovascular hypertrophy and remodeling in mice

(2010) Michael G. Usher et al.   JOURNAL OF CLINICAL INVESTIGATION

Eplerenone in Patients with Systolic Heart Failure and Mild Symptoms

(2010) Faiez Zannad et al.   NEW ENGLAND JOURNAL OF MEDICINE

Myeloid-Specific Deletion of the Mineralocorticoid Receptor Reduces Infarct Volume and Alters Inflammation During Cerebral Ischemia

(2010) Ryan A. Frieler et al.   STROKE

Low Renal Mineralocorticoid Receptor Expression at Birth Contributes to Partial Aldosterone Resistance in Neonates

(2009) Laetitia Martinerie et al.   ENDOCRINOLOGY

Mineralocorticoid receptors in control of emotional arousal and fear memory

(2009) V. Brinks et al.   HORMONES AND BEHAVIOR

Deletion of Mineralocorticoid Receptors From Macrophages Protects Against Deoxycorticosterone/Salt-Induced Cardiac Fibrosis and Increased Blood Pressure

(2009) Amanda J. Rickard et al.   HYPERTENSION

The balance between gluco- and mineralo-corticoid action critically determines inflammatory adipocyte responses

(2009) J Hoppmann et al.   JOURNAL OF ENDOCRINOLOGY

RNAi inhibition of mineralocorticoid receptors prevents the development of cold-induced hypertension

(2008) Zhongjie Sun et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Silencing of the Mineralocorticoid Receptor by Ribonucleic Acid Interference in Transgenic Rats Disrupts Endocrine Homeostasis

(2008) Hee-Young Lim et al.   MOLECULAR ENDOCRINOLOGY

Hypothalamic–pituitary–adrenal axis dysregulation and behavioral analysis of mouse mutants with altered glucocorticoid or mineralocorticoid receptor function

(2008) Benedict J. Kolber et al.   STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS