Finerenone Impedes Aldosterone-dependent Nuclear Import of the Mineralocorticoid Receptor and Prevents Genomic Recruitment of Steroid Receptor Coactivator-1

Cistrome of the aldosterone-activated mineralocorticoid receptor in human renal cells

(2015) Florian Le Billan et al.   FASEB JOURNAL

Finerenone, a Novel Selective Nonsteroidal Mineralocorticoid Receptor Antagonist Protects From Rat Cardiorenal Injury

(2014) Peter Kolkhof et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Safety and tolerability of the novel non-steroidal mineralocorticoid receptor antagonist BAY 94-8862 in patients with chronic heart failure and mild or moderate chronic kidney disease: a randomized, double-blind trial

(2013) Bertram Pitt et al.   EUROPEAN HEART JOURNAL

A New Strategy for Selective Targeting of Progesterone Receptor With Passive Antagonists

(2013) Junaid A. Khan et al.   MOLECULAR ENDOCRINOLOGY

Rapid mineralocorticoid receptor trafficking

(2013) M. Gekle et al.   STEROIDS

Nuclear Shuttling Precedes Dimerization in Mineralocorticoid Receptor Signaling

(2012) Claudia Grossmann et al.   CHEMISTRY & BIOLOGY

Discovery of BAY 94-8862: A Nonsteroidal Antagonist of the Mineralocorticoid Receptor for the Treatment of Cardiorenal Diseases

(2012) Lars Bärfacker et al.   ChemMedChem

Differential ubiquitylation of the mineralocorticoid receptor is regulated by phosphorylation

(2012) Nourdine Faresse et al.   FASEB JOURNAL

Molecular pharmacology of the mineralocorticoid receptor: Prospects for novel therapeutics

(2011) Peter Kolkhof et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Ligand-Dependent Degradation of SRC-1 Is Pivotal for Progesterone Receptor Transcriptional Activity

(2011) Larbi Amazit et al.   MOLECULAR ENDOCRINOLOGY

Minireview: Aldosterone and Mineralocorticoid Receptors: Past, Present, and Future

(2010) John W. Funder   ENDOCRINOLOGY

A New Mode of Mineralocorticoid Receptor Antagonism by a Potent and Selective Nonsteroidal Molecule

(2010) Jérôme Fagart et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Osmotic Stress Regulates Mineralocorticoid Receptor Expression in a Novel Aldosterone-Sensitive Cortical Collecting Duct Cell Line

(2009) Say Viengchareun et al.   MOLECULAR ENDOCRINOLOGY

Aldosterone and arterial hypertension

(2009) Andreas Tomaschitz et al.   Nature Reviews Endocrinology

Helix 3–helix 5 interactions in steroid hormone receptor function

(2008) Junhui Zhang et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY