Biopsy-derived Intestinal Epithelial Cell Cultures for Pathway-based Stratification of Patients With Inflammatory Bowel Disease

Defective ATG16L1-mediated removal of IRE1α drives Crohn’s disease–like ileitis

(2017) Markus Tschurtschenthaler et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Tauroursodeoxycholic acid protects bile acid homeostasis under inflammatory conditions and dampens Crohn’s disease-like ileitis

(2017) Lien Van den Bossche et al.   LABORATORY INVESTIGATION

Epithelial ER Stress in Crohnʼs Disease and Ulcerative Colitis

(2016) Stewart S. Cao   INFLAMMATORY BOWEL DISEASES

Tauroursodeoxycholate improves 2,4,6-trinitrobenzenesulfonic acid-induced experimental acute ulcerative colitis in mice

(2016) Yang Yang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Therapeutic innovations in inflammatory bowel diseases

(2015) W Vanhove et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Role of endoplasmic reticulum stress and autophagy as interlinking pathways in the pathogenesis of inflammatory bowel disease

(2015) Shuhei Hosomi et al.   CURRENT OPINION IN GASTROENTEROLOGY

Immunopathogenesis of IBD: current state of the art

(2015) Heitor S. P. de Souza et al.   Nature Reviews Gastroenterology & Hepatology

Mongersen, an Oral SMAD7 Antisense Oligonucleotide, and Crohn’s Disease

(2015) Giovanni Monteleone et al.   NEW ENGLAND JOURNAL OF MEDICINE

Biologics in inflammatory bowel disease: what are the data?

(2015) Justin Côté-Daigneault et al.   United European Gastroenterology Journal

The use of sirolimus (rapamycin) in the management of refractory inflammatory bowel disease in children

(2014) Mohamed Mutalib et al.   Journal of Crohns & Colitis

Tauroursodeoxycholic acid inhibits experimental colitis by preventing early intestinal epithelial cell death

(2014) Debby Laukens et al.   LABORATORY INVESTIGATION

Etrolizumab as induction therapy for ulcerative colitis: a randomised, controlled, phase 2 trial

(2014) Séverine Vermeire et al.   LANCET

Genetic association and functional role of Crohn disease risk alleles involved in microbial sensing, autophagy, and endoplasmic reticulum (ER) stress

(2013) Eveline Hoefkens et al.   Autophagy

Targeting TNF-α for the treatment of inflammatory bowel disease

(2013) Thomas Billiet et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

The Unfolded Protein Response and Chemical Chaperones Reduce Protein Misfolding and Colitis in Mice

(2013) Stewart Siyan Cao et al.   GASTROENTEROLOGY

Genomic ATG16L1 risk allele-restricted Paneth cell ER stress in quiescent Crohn's disease

(2013) J Jasper Deuring et al.   GUT

Paneth cells as a site of origin for intestinal inflammation

(2013) Timon E. Adolph et al.   NATURE

Sodium 4-phenylbutyrate suppresses the development of dextran sulfate sodium-induced colitis in mice

(2013) KAZUHIKO ONO et al.   Experimental and Therapeutic Medicine

Predicting the Course of IBD: Light at the End of the Tunnel?

(2012) James C. Lee   DIGESTIVE DISEASES

Towards a Novel Molecular Classification of IBD

(2012) Severine Vermeire   DIGESTIVE DISEASES

Keratins in colorectal epithelial function and disease

(2012) Debabrata Majumdar et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

(2012) Luke Jostins et al.   NATURE

Glutamine Treatment Attenuates Endoplasmic Reticulum Stress and Apoptosis in TNBS-Induced Colitis

(2012) Irene Crespo et al.   PLoS One

Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium

(2011) Toshiro Sato et al.   GASTROENTEROLOGY

Crohn's disease: NOD2, autophagy and ER stress converge

(2011) T. Fritz et al.   GUT

Tauroursodeoxycholic Acid May Improve Liver and Muscle but Not Adipose Tissue Insulin Sensitivity in Obese Men and Women

(2010) Marleen Kars et al.   DIABETES

Genetic variation in the autophagy gene ULK1 and risk of Crohnʼs disease

(2010) Liesbet Henckaerts et al.   INFLAMMATORY BOWEL DISEASES

A Key Role for E-cadherin in Intestinal Homeostasis and Paneth Cell Maturation

(2010) Marlon R. Schneider et al.   PLoS One

Toward unraveling the complexity of simple epithelial keratins in human disease

(2009) M. Bishr Omary et al.   JOURNAL OF CLINICAL INVESTIGATION

A Multicenter, Randomized, Double-Blind Trial of EverolimusVersusAzathioprine and Placebo to Maintain Steroid-Induced Remission in Patients With Moderate-to-Severe Active Crohn's Disease

(2008) Walter Reinisch et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

The cell-cell adhesion molecule E-cadherin

(2008) F. van Roy et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Use of sirolimus (rapamycin) to treat refractory Crohn's disease

(2008) D C O Massey et al.   GUT

Everolimus for refractory Crohnʼs disease: A case report

(2008) Jérôme Dumortier et al.   INFLAMMATORY BOWEL DISEASES