Seizure frequency correlates with loss of dentate gyrus GABAergic neurons in a mouse model of temporal lobe epilepsy

Hilar somatostatin interneuron loss reduces dentate gyrus inhibition in a mouse model of temporal lobe epilepsy

(2016) Gabrielle Hofmann et al.   EPILEPSIA

Regulation of astrocyte glutamate transporter-1 (GLT1) and aquaporin-4 (AQP4) expression in a model of epilepsy

(2016) Jacqueline A. Hubbard et al.   EXPERIMENTAL NEUROLOGY

Ablation of Newly Generated Hippocampal Granule Cells Has Disease-Modifying Effects in Epilepsy

(2016) B. E. Hosford et al.   JOURNAL OF NEUROSCIENCE

Glia as drivers of abnormal neuronal activity

(2016) Stefanie Robel et al.   NATURE NEUROSCIENCE

Adenosinergic signaling in epilepsy

(2016) Detlev Boison   NEUROPHARMACOLOGY

Conditional Disabled-1 Deletion in Mice Alters Hippocampal Neurogenesis and Reduces Seizure Threshold

(2016) Matthew J. Korn et al.   Frontiers in Neuroscience

Dentate total molecular layer interneurons mediate cannabinoid-sensitive inhibition

(2015) Jiandong Yu et al.   HIPPOCAMPUS

Reactive Astrogliosis Causes the Development of Spontaneous Seizures

(2015) S. Robel et al.   JOURNAL OF NEUROSCIENCE

The Severity of Gliosis in Hippocampal Sclerosis Correlates with Pre-Operative Seizure Burden and Outcome After Temporal Lobectomy

(2015) Alexandra M. Johnson et al.   MOLECULAR NEUROBIOLOGY

Aberrant hippocampal neurogenesis contributes to epilepsy and associated cognitive decline

(2015) Kyung-Ok Cho et al.   Nature Communications

Degeneration and Regeneration of GABAergic Interneurons in the Dentate Gyrus of Adult Mice in Experimental Models of Epilepsy

(2014) Dong Wei et al.   CNS Neuroscience & Therapeutics

Surviving mossy cells enlarge and receive more excitatory synaptic input in a mouse model of temporal lobe epilepsy

(2014) Wei Zhang et al.   HIPPOCAMPUS

Long-Term Seizure Suppression and Optogenetic Analyses of Synaptic Connectivity in Epileptic Mice with Hippocampal Grafts of GABAergic Interneurons

(2014) K. W. Henderson et al.   JOURNAL OF NEUROSCIENCE

Fast-spiking, parvalbumin+ GABAergic interneurons: From cellular design to microcircuit function

(2014) H. Hu et al.   SCIENCE

Loss of hippocampal interneurons and epileptogenesis: a comparison of two animal models of acquired epilepsy

(2013) Noora Huusko et al.   Brain Structure & Function

High-dose rapamycin blocks mossy fiber sprouting but not seizures in a mouse model of temporal lobe epilepsy

(2013) Kathleen Heng et al.   EPILEPSIA

A Sensitive Period for GABAergic Interneurons in the Dentate Gyrus in Modulating Sensorimotor Gating

(2013) N. Guo et al.   JOURNAL OF NEUROSCIENCE

Accumulation of Abnormal Adult-Generated Hippocampal Granule Cells Predicts Seizure Frequency and Severity

(2013) M. S. Hester et al.   JOURNAL OF NEUROSCIENCE

Early Activation of Ventral Hippocampus and Subiculum during Spontaneous Seizures in a Rat Model of Temporal Lobe Epilepsy

(2013) I. Toyoda et al.   JOURNAL OF NEUROSCIENCE

A Reorganized GABAergic Circuit in a Model of Epilepsy: Evidence from Optogenetic Labeling and Stimulation of Somatostatin Interneurons

(2013) Z. Peng et al.   JOURNAL OF NEUROSCIENCE

GABA progenitors grafted into the adult epileptic brain control seizures and abnormal behavior

(2013) Robert F Hunt et al.   NATURE NEUROSCIENCE

Rapamycin Attenuates the Development of Posttraumatic Epilepsy in a Mouse Model of Traumatic Brain Injury

(2013) Dongjun Guo et al.   PLoS One

The Influence of Ectopic Migration of Granule Cells into the Hilus on Dentate Gyrus-CA3 Function

(2013) Catherine E. Myers et al.   PLoS One

Astrocyte control of synaptic NMDA receptors contributes to the progressive development of temporal lobe epilepsy

(2013) J. Clasadonte et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Variability of sclerosis along the longitudinal hippocampal axis in epilepsy: A post mortem study

(2012) Maria Thom et al.   EPILEPSY RESEARCH

Rapid epileptogenesis in the mouse pilocarpine model: Video-EEG, pharmacokinetic and histopathological characterization

(2012) Manuela Mazzuferi et al.   EXPERIMENTAL NEUROLOGY

GABAergic excitation after febrile seizures induces ectopic granule cells and adult epilepsy

(2012) Ryuta Koyama et al.   NATURE MEDICINE

Contributions of astrocytes to epileptogenesis following status epilepticus: Opportunities for preventive therapy?

(2012) M.B. Gibbons et al.   NEUROCHEMISTRY INTERNATIONAL

Hilar Mossy Cell Degeneration Causes Transient Dentate Granule Cell Hyperexcitability and Impaired Pattern Separation

(2012) Seiichiro Jinde et al.   NEURON

Excessive Activation of mTOR in Postnatally Generated Granule Cells Is Sufficient to Cause Epilepsy

(2012) Raymund Y.K. Pun et al.   NEURON

Hippocampal tissue of patients with refractory temporal lobe epilepsy is associated with astrocyte activation, inflammation, and altered expression of channels and receptors

(2012) A. Das et al.   NEUROSCIENCE

Is there a critical period for mossy fiber sprouting in a mouse model of temporal lobe epilepsy?

(2011) Felicia H. Lew et al.   EPILEPSIA

Morphologic integration of hilar ectopic granule cells into dentate gyrus circuitry in the pilocarpine model of temporal lobe epilepsy

(2011) Michael C. Cameron et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Rapamycin Suppresses Mossy Fiber Sprouting But Not Seizure Frequency in a Mouse Model of Temporal Lobe Epilepsy

(2011) P. S. Buckmaster et al.   JOURNAL OF NEUROSCIENCE

Loss and reorganization of calretinin-containing interneurons in the epileptic human hippocampus

(2010) K. Toth et al.   BRAIN

Expression of COUP-TFII Nuclear Receptor in Restricted GABAergic Neuronal Populations in the Adult Rat Hippocampus

(2010) P. Fuentealba et al.   JOURNAL OF NEUROSCIENCE

Toll-like receptor 4 and high-mobility group box-1 are involved in ictogenesis and can be targeted to reduce seizures

(2010) Mattia Maroso et al.   NATURE MEDICINE

Selective induction of astrocytic gliosis generates deficits in neuronal inhibition

(2010) Pavel I Ortinski et al.   NATURE NEUROSCIENCE

Prox1 Is Required for Granule Cell Maturation and Intermediate Progenitor Maintenance During Brain Neurogenesis

(2010) Alfonso Lavado et al.   PLOS BIOLOGY

Initial loss but later excess of GABAergic synapses with dentate granule cells in a rat model of temporal lobe epilepsy

(2009) Khushdev K. Thind et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Surviving Hilar Somatostatin Interneurons Enlarge, Sprout Axons, and Form New Synapses with Granule Cells in a Mouse Model of Temporal Lobe Epilepsy

(2009) W. Zhang et al.   JOURNAL OF NEUROSCIENCE

Survival of mossy cells of the hippocampal dentate gyrus in humans with mesial temporal lobe epilepsy

(2009) László Seress et al.   JOURNAL OF NEUROSURGERY

Loss of Astrocytic Domain Organization in the Epileptic Brain

(2008) N. A. Oberheim et al.   JOURNAL OF NEUROSCIENCE

Astrocytes in the Epileptic Brain

(2008) Jonathon Wetherington et al.   NEURON