GLP-1 Receptor Activation Inhibits Palmitate-Induced Apoptosis via Ceramide in Human Cardiac Progenitor Cells

Palmitate promotes autophagy and apoptosis through ROS-dependent JNK and p38 MAPK

(2015) Jing Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

p38α mitogen-activated kinase mediates cardiomyocyte apoptosis induced by palmitate

(2014) Charles C. Oh et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cardiomyocyte-specific Loss of Diacylglycerol Acyltransferase 1 (DGAT1) Reproduces the Abnormalities in Lipids Found in Severe Heart Failure

(2014) Li Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Palmitate Induces ER Stress and Autophagy in H9c2 Cells: Implications for Apoptosis and Adiponectin Resistance

(2014) Min Park et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Glucagon-like peptide-1 receptor activation reverses cardiac remodeling via normalizing cardiac steatosis and oxidative stress in type 2 diabetes

(2013) Akio Monji et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Extraglycemic effects of glp-1-based therapeutics: Addressing metabolic and cardiovascular risks associated with type 2 diabetes

(2013) Susan Herzlinger et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Exendin-4 protects pancreatic beta cells from palmitate-induced apoptosis by interfering with GPR40 and the MKK4/7 stress kinase signalling pathway

(2013) Annalisa Natalicchio et al.   DIABETOLOGIA

Exendin-4 protects endothelial cells from lipoapoptosis by PKA, PI3K, eNOS, p38 MAPK, and JNK pathways

(2013) Özlem Erdogdu et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Palmitate induces H9c2 cell apoptosis by increasing reactive oxygen species generation and activation of the ERK1/2 signaling pathway

(2013) CHUAN-DONG WEI et al.   Molecular Medicine Reports

Pravastatin slows the progression of heart failure by inhibiting the c-Jun N-terminal kinase-mediated intrinsic apoptotic signaling pathway

(2013) SHIPING CAO et al.   Molecular Medicine Reports

Abnormalities of the cardiac stem and progenitor cell compartment in experimental and human diabetes

(2013) Anna Leonardini et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

Ceramide synthases at the centre of sphingolipid metabolism and biology

(2012) Thomas D. Mullen et al.   BIOCHEMICAL JOURNAL

Lipid Metabolism and Toxicity in the Heart

(2012) Ira J. Goldberg et al.   Cell Metabolism

A Glucagon-Like Peptide-1 Analog Reverses the Molecular Pathology and Cardiac Dysfunction of a Mouse Model of Obesity

(2012) Mohammad Hossein Noyan-Ashraf et al.   CIRCULATION

GLP-1 receptor agonists: A clinical perspective on cardiovascular effects

(2012) Dhanwantee Mundil et al.   Diabetes & Vascular Disease Research

Glucagon-Like Peptide-1 Counteracts Oxidative Stress-Dependent Apoptosis of Human Cardiac Progenitor Cells by Inhibiting the Activation of the c-Jun N-terminal Protein Kinase Signaling Pathway

(2012) L. Laviola et al.   ENDOCRINOLOGY

Sphingolipids, Lipotoxic Cardiomyopathy, and Cardiac Failure

(2012) Tae-Sik Park et al.   Heart Failure Clinics

MicroRNA-195 promotes palmitate-induced apoptosis in cardiomyocytes by down-regulating Sirt1

(2011) Huaqing Zhu et al.   CARDIOVASCULAR RESEARCH

Role of Cardiac Stem Cells in Cardiac Pathophysiology: A Paradigm Shift in Human Myocardial Biology

(2011) Annarosa Leri et al.   CIRCULATION RESEARCH

The challenge to verify ceramide's role of apoptosis induction in human cardiomyocytes - a pilot study

(2011) Engin Usta et al.   Journal of Cardiothoracic Surgery

Mesenchymal stem cells or cardiac progenitors for cardiac repair? A comparative study

(2010) Remco Koninckx et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Ceramide synthases 2, 5, and 6 confer distinct roles in radiation-induced apoptosis in HeLa cells

(2010) Judith Mesicek et al.   CELLULAR SIGNALLING

Myocardium of type 2 diabetic and obese patients is characterized by alterations in sphingolipid metabolic enzymes but not by accumulation of ceramide

(2009) Marcin Baranowski et al.   JOURNAL OF LIPID RESEARCH

Ceramide is a cardiotoxin in lipotoxic cardiomyopathy

(2008) Tae-Sik Park et al.   JOURNAL OF LIPID RESEARCH

Cardiac stem cells and myocardial disease

(2008) Jan Kajstura et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY