Note: MSM lag time cannot be used for variational model selection

Optimized parameter selection reveals trends in Markov state models for protein folding

(2016) Brooke E. Husic et al.   JOURNAL OF CHEMICAL PHYSICS

Efficient maximum likelihood parameterization of continuous-time Markov processes

(2015) Robert T. McGibbon et al.   JOURNAL OF CHEMICAL PHYSICS

Variational cross-validation of slow dynamical modes in molecular kinetics

(2015) Robert T. McGibbon et al.   JOURNAL OF CHEMICAL PHYSICS

Modeling Molecular Kinetics with tICA and the Kernel Trick

(2015) Christian R. Schwantes et al.   Journal of Chemical Theory and Computation

Identification of slow molecular order parameters for Markov model construction

(2013) Guillermo Pérez-Hernández et al.   JOURNAL OF CHEMICAL PHYSICS

A Variational Approach to Modeling Slow Processes in Stochastic Dynamical Systems

(2013) Frank Noé et al.   MULTISCALE MODELING & SIMULATION