Acid–base regulation and sensing: Accelerators and brakes in metabolic regulation of cerebrovascular tone

Intravital investigation of rat mesenteric small artery tone and blood flow

(2017) Jakob Nyvad et al.   JOURNAL OF PHYSIOLOGY-LONDON

Capillary K+-sensing initiates retrograde hyperpolarization to increase local cerebral blood flow

(2017) Thomas A Longden et al.   NATURE NEUROSCIENCE

Crosstalk between cardiomyocyte-rich perivascular tissue and coronary arteries is reduced in the Zucker Diabetic Fatty rat model of type 2 diabetes mellitus

(2016) L. Bonde et al.   Acta Physiologica

EDH: endothelium-dependent hyperpolarization and microvascular signalling

(2016) C. J. Garland et al.   Acta Physiologica

The Hypertension Risk Variant Rs820430 Functions as an Enhancer ofSLC4A7

(2016) Laiyuan Wang et al.   AMERICAN JOURNAL OF HYPERTENSION

Na+, HCO3−-cotransporter NBCn1 increases pHigradients, filopodia, and migration of smooth muscle cells and promotes arterial remodelling

(2016) Ebbe Boedtkjer et al.   CARDIOVASCULAR RESEARCH

Genetically encoded indicators of neuronal activity

(2016) Michael Z Lin et al.   NATURE NEUROSCIENCE

Negative News: Cl− and HCO3− in the Vascular Wall

(2016) Ebbe Boedtkjer et al.   PHYSIOLOGY

New roles of factors from perivascular tissue in regulation of vascular tone

(2015) U. Simonsen et al.   Acta Physiologica

Extracellular ʜ ᴄ ᴏ3̅ is sensed by mouse cerebral arteries: Regulation of tone by receptor protein tyrosine phosphatase γ

(2015) Ebbe Boedtkjer et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Perivascular tissue inhibits rho-kinase-dependent smooth muscle Ca2+sensitivity and endothelium-dependent H2S signalling in rat coronary arteries

(2015) Filip Aalbaek et al.   JOURNAL OF PHYSIOLOGY-LONDON

Synthesis of N-cyano-substituted sulfilimine and sulfoximine derivatives of S0859 and their biological evaluation as sodium bicarbonate co-transport inhibitors

(2015) Anne-Dorothee Steinkamp et al.   MedChemComm

Dorzolamide-induced relaxation of porcine retinal arterioles in vitro depends on nitric oxide but not on acidosis in vascular smooth muscle cells

(2014) A. El-Galaly et al.   EXPERIMENTAL EYE RESEARCH

Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension

(2014) Xiangfeng Lu et al.   HUMAN MOLECULAR GENETICS

Direct Evidence for Calcineurin Binding to the Exon-7 Loop of the Sodium-Bicarbonate Cotransporter NBCn1

(2014) Harindarpal S. Gill et al.   International Journal of Biological Sciences

The Vascular Steal Phenomenon is an Incomplete Contributor to Negative Cerebrovascular Reactivity in Patients with Symptomatic Intracranial Stenosis

(2014) Daniel F Arteaga et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

PKA and Epac activation mediates cAMP-induced vasorelaxation by increasing endothelial NO production

(2014) Verónica García-Morales et al.   VASCULAR PHARMACOLOGY

Perivascular adipose tissue-derived adiponectin activates BKCa channels to induce anticontractile responses

(2013) Fiona M. Lynch et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Bicarbonate disruption of the pulmonary endothelial barrier via activation of endogenous soluble adenylyl cyclase, isoform 10

(2013) Boniface Obiako et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Splice Cassette II of Na+,HCO3−Cotransporter NBCn1 (slc4a7) Interacts with Calcineurin A

(2013) Andreas A. Danielsen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Vascular Conducted Response in Cerebral Blood Flow Regulation

(2013) Lars Jørn Jensen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Intracellular Acidification Alters Myogenic Responsiveness and Vasomotion of Mouse Middle Cerebral Arteries

(2013) Axel BK Thomsen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Endothelial alkalinisation inhibits gap junction communication and endothelium-derived hyperpolarisations in mouse mesenteric arteries

(2013) Ebbe Boedtkjer et al.   JOURNAL OF PHYSIOLOGY-LONDON

Effects of Bariatric Surgery on Human Small Artery Function

(2013) Reza Aghamohammadzadeh et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Coupled Ca2+/H+ transport by cytoplasmic buffers regulates local Ca2+ and H+ ion signaling

(2013) P. Swietach et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Disturbed acid-base transport: an emerging cause of hypertension

(2013) Ebbe Boedtkjer et al.   Frontiers in Physiology

Gram-Scale Solution-Phase Synthesis of Selective Sodium Bicarbonate Co-transport Inhibitor S0859: in vitro Efficacy Studies in Breast Cancer Cells

(2012) Ann M. Larsen et al.   ChemMedChem

Dorzolamide-induced Relaxation of Intraocular Porcine Ciliary Arteries In Vitro Depends on Nitric Oxide and the Vascular Endothelium

(2012) Sidse Kringelholt et al.   CURRENT EYE RESEARCH

Physiology, Pharmacology and Pathophysiology of the pH Regulatory Transport Proteins NHE1 and NBCn1: Similarities, Differences, and Implications for Cancer Therapy

(2012) E. Boedtkjer et al.   CURRENT PHARMACEUTICAL DESIGN

Mechanisms underlying blood-brain barrier dysfunction in brain pathology and epileptogenesis: Role of astroglia

(2012) Richard Kovács et al.   EPILEPSIA

Role of KCNQ Channels in Skeletal Muscle Arteries and Periadventitial Vascular Dysfunction

(2012) Olga Zavaritskaya et al.   HYPERTENSION

Conditioning the whole heart—not just the cardiomyocyte

(2012) Robert M. Bell et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Soluble Adenylyl Cyclase Activity Is Necessary for Retinal Ganglion Cell Survival and Axon Growth

(2012) R. G. Corredor et al.   JOURNAL OF NEUROSCIENCE

NHE1 knockout reduces blood pressure and arterial media/lumen ratio with no effect on resting pHiin the vascular wall

(2012) Ebbe Boedtkjer et al.   JOURNAL OF PHYSIOLOGY-LONDON

Intracellular pH in the Resistance Vasculature: Regulation and Functional Implications

(2012) Ebbe Boedtkjer et al.   JOURNAL OF VASCULAR RESEARCH

Acid–base transporters modulate cell migration, growth and proliferation: Implications for structure development and remodeling of resistance arteries?

(2012) Ebbe Boedtkjer et al.   TRENDS IN CARDIOVASCULAR MEDICINE

pCO2 and pH regulation of cerebral blood flow

(2012) SeongHun Yoon et al.   Frontiers in Physiology

Vasomotion - what is currently thought?

(2011) C. Aalkjaer et al.   Acta Physiologica

Silencing of Sodium–Hydrogen Exchanger 1 Attenuates the Proliferation, Hypertrophy, and Migration of Pulmonary Artery Smooth Muscle Cells via E2F1

(2011) Lunyin Yu et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Disruption of Na + ,HCO 3 − Cotransporter NBCn1 (slc4a7) Inhibits NO-Mediated Vasorelaxation, Smooth Muscle Ca 2+ Sensitivity, and Hypertension Development in Mice

(2011) Ebbe Boedtkjer et al.   CIRCULATION

Acidosis Dilates Brain Parenchymal Arterioles by Conversion of Calcium Waves to Sparks to Activate BK Channels

(2011) Fabrice Dabertrand et al.   CIRCULATION RESEARCH

Neurovascular function in Alzheimer's disease patients and experimental models

(2011) Nektaria Nicolakakis et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

(2011) Georg B. Ehret et al.   NATURE

Control of muscle blood flow during exercise: local factors and integrative mechanisms

(2010) I. Sarelius et al.   Acta Physiologica

Glial and neuronal control of brain blood flow

(2010) David Attwell et al.   NATURE

Sarcoplasmic Reticulum Function in Smooth Muscle

(2010) Susan Wray et al.   PHYSIOLOGICAL REVIEWS

Different pathways with distinct properties conduct dilations in the microcirculation in vivo

(2009) Cor de Wit   CARDIOVASCULAR RESEARCH

Local Inflammation and Hypoxia Abolish the Protective Anticontractile Properties of Perivascular Fat in Obese Patients

(2009) Adam S. Greenstein et al.   CIRCULATION

Proton Acts as a Neurotransmitter for Nicotine-Induced Adrenergic and Calcitonin Gene-Related Peptide-Containing Nerve-Mediated Vasodilation in the Rat Mesenteric Artery

(2009) H. Kawasaki et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Acetazolamide induces indomethacin and ischaemia-sensitive pial arteriolar vasodilation in the piglet

(2008) Ferenc Domoki et al.   ACTA PAEDIATRICA

Insulin inhibits Na+/H+ exchange in vascular smooth muscle and endothelial cells in situ: involvement of H2O2 and tyrosine phosphatase SHP-2

(2008) Ebbe Boedtkjer et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Deficiency of the NHE1 Gene Prevents Hypoxia-induced Pulmonary Hypertension and Vascular Remodeling

(2008) Lunyin Yu et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Sensing Tension

(2008) Heather A. Drummond et al.   HYPERTENSION

Regulation of neuronal connexin-36 channels by pH

(2008) D. Gonzalez-Nieto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA