Optimized tPA: A non-neurotoxic fibrinolytic agent for the drainage of intracerebral hemorrhages

Thrombolytic removal of intraventricular haemorrhage in treatment of severe stroke: results of the randomised, multicentre, multiregion, placebo-controlled CLEAR III trial

(2017) Daniel F Hanley et al.   LANCET

Critical Illness Is Associated With Impaired Gallbladder Emptying as Assessed by 3D Ultrasound

(2016) Mark P. Plummer et al.   CRITICAL CARE MEDICINE

Safety and efficacy of minimally invasive surgery plus alteplase in intracerebral haemorrhage evacuation (MISTIE): a randomised, controlled, open-label, phase 2 trial

(2016) Daniel F Hanley et al.   LANCET NEUROLOGY

Targeting secondary injury in intracerebral haemorrhage—perihaematomal oedema

(2015) Sebastian Urday et al.   Nature Reviews Neurology

Perihematomal Edema and Functional Outcomes in Intracerebral Hemorrhage

(2015) Santosh B. Murthy et al.   STROKE

Guidelines for the Management of Spontaneous Intracerebral Hemorrhage

(2015) J. Claude Hemphill et al.   STROKE

Impacts of tissue-type plasminogen activator (tPA) on neuronal survival

(2015) Arnaud Chevilley et al.   Frontiers in Cellular Neuroscience

Intracerebral hemorrhage in mouse models: therapeutic interventions and functional recovery

(2014) Balachandar Kathirvelu et al.   METABOLIC BRAIN DISEASE

Urokinase versus Alteplase for intraventricular hemorrhage fibrinolysis

(2014) Thomas Gaberel et al.   NEUROPHARMACOLOGY

Volume-dependent effect of perihaematomal oedema on outcome for spontaneous intracerebral haemorrhages

(2013) G. Appelboom et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Molecular requirements for safer generation of thrombolytics by bioengineering the tissue-type plasminogen activator A chain

(2013) J. Parcq et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Surgery for cerebral haemorrhage—STICH II trial

(2013) Thomas Gaberel et al.   LANCET

Early surgery versus initial conservative treatment in patients with spontaneous supratentorial lobar intracerebral haematomas (STICH II): a randomised trial

(2013) A David Mendelow et al.   LANCET

Neuroendoscopic Surgery versus External Ventricular Drainage Alone or with Intraventricular Fibrinolysis for Intraventricular Hemorrhage Secondary to Spontaneous Supratentorial Hemorrhage: A Systematic Review and Meta-Analysis

(2013) Yuping Li et al.   PLoS One

Minimally Invasive Surgery Plus Recombinant Tissue-type Plasminogen Activator for Intracerebral Hemorrhage Evacuation Decreases Perihematomal Edema

(2013) W. Andrew Mould et al.   STROKE

Unveiling an exceptional zymogen: the single-chain form of tPA is a selective activator of NMDA receptor-dependent signaling and neurotoxicity

(2012) J Parcq et al.   CELL DEATH AND DIFFERENTIATION

Intracerebral haemorrhage: mechanisms of injury and therapeutic targets

(2012) Richard F Keep et al.   LANCET NEUROLOGY

Tissue Plasminogen Activator Induced Delayed Edema in Experimental Porcine Intracranial Hemorrhage: Reduction with Plasminogen Activator Inhibitor-1 Administration

(2012) Naureen Keric et al.   Translational Stroke Research

Deferoxamine Treatment for Intracerebral Hemorrhage in Aged Rats

(2010) Masanobu Okauchi et al.   STROKE

Iron-Related Brain Damage in Patients With Intracerebral Hemorrhage

(2010) Natalia Pérez de la Ossa et al.   STROKE

Guidelines for the Management of Spontaneous Intracerebral Hemorrhage

(2010) Lewis B. Morgenstern et al.   STROKE

The complement cascade as a therapeutic target in intracerebral hemorrhage

(2009) Andrew F. Ducruet et al.   EXPERIMENTAL NEUROLOGY

Significance of perihematomal edema in acute intracerebral hemorrhage: The INTERACT trial

(2009) H. Arima et al.   NEUROLOGY

Toward Safer Thrombolytic Agents in Stroke: Molecular Requirements for NMDA Receptor-Mediated Neurotoxicity

(2008) Jose P Lopez-Atalaya et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM