Transferrin receptor (TfR) trafficking determines brain uptake of TfR antibody affinity variants

Study of the transcytosis of an anti-transferrin receptor antibody with a Fab′ cargo across the blood–brain barrier in mice

(2013) Gemma Manich et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Developing Therapeutic Antibodies for Neurodegenerative Disease

(2013) Y. Joy Yu et al.   Neurotherapeutics

Addressing Safety Liabilities of TfR Bispecific Antibodies That Cross the Blood-Brain Barrier

(2013) J. A. Couch et al.   Science Translational Medicine

Compartmental Tissue Distribution of Antibody Therapeutics: Experimental Approaches and Interpretations

(2012) C. Andrew Boswell et al.   AAPS Journal

Reducing Human Apolipoprotein E Levels Attenuates Age-Dependent A  Accumulation in Mutant Human Amyloid Precursor Protein Transgenic Mice

(2012) N. Bien-Ly et al.   JOURNAL OF NEUROSCIENCE

In Vivo Labeling of Brain Capillary Endothelial Cells after Intravenous Injection of Monoclonal Antibodies Targeting the Transferrin Receptor

(2011) S. Paris-Robidas et al.   MOLECULAR PHARMACOLOGY

A Therapeutic Antibody Targeting BACE1 Inhibits Amyloid-  Production in Vivo

(2011) J. K. Atwal et al.   Science Translational Medicine

Boosting Brain Uptake of a Therapeutic Antibody by Reducing Its Affinity for a Transcytosis Target

(2011) Y. J. Yu et al.   Science Translational Medicine

Small GTPase Rab12 Regulates Constitutive Degradation of Transferrin Receptor

(2011) Takahide Matsui et al.   TRAFFIC

Spatial control of EGF receptor activation by reversible dimerization on living cells

(2010) Inhee Chung et al.   NATURE

Long-term, high-resolution imaging in the mouse neocortex through a chronic cranial window

(2009) Anthony Holtmaat et al.   Nature Protocols

Restricted transport of anti-transferrin receptor antibody (OX26) through the blood-brain barrier in the rat

(2003) Torben Moos et al.   JOURNAL OF NEUROCHEMISTRY