Cerebral artery myogenic reactivity: The next frontier in developing effective interventions for subarachnoid hemorrhage

Relationship between cognitive function and regulation of cerebral blood flow

(2017) Shigehiko Ogoh   Journal of Physiological Sciences

Size-selective opening of the blood–brain barrier by targeting endothelial sphingosine 1–phosphate receptor 1

(2017) Keisuke Yanagida et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Constitutive smooth muscle tumour necrosis factor regulates microvascular myogenic responsiveness and systemic blood pressure

(2017) Jeffrey T. Kroetsch et al.   Nature Communications

Alpha Calcitonin Gene-Related Peptide Increases Cerebral Vessel Diameter in Animal Models of Subarachnoid Hemorrhage: A Systematic Review and Meta-analysis

(2017) Liam M. C. Flynn et al.   Frontiers in Neurology

Delayed cerebral ischaemia prevention and treatment after aneurysmal subarachnoid haemorrhage: a systematic review

(2016) M. Veldeman et al.   BRITISH JOURNAL OF ANAESTHESIA

Aneurysmal Subarachnoid Hemorrhage and Neuroinflammation: A Comprehensive Review

(2016) Brandon Lucke-Wold et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A Phase I proof-of-concept and safety trial of sildenafil to treat cerebral vasospasm following subarachnoid hemorrhage

(2016) Chad W. Washington et al.   JOURNAL OF NEUROSURGERY

Myogenic and metabolic feedback in cerebral autoregulation: Putative involvement of arachidonic acid-dependent pathways

(2016) Ronan M.G. Berg   MEDICAL HYPOTHESES

Acute Effect of Intravenous Sildenafil on Cerebral Blood Flow in Patients with Vasospasm After Subarachnoid Hemorrhage

(2016) Rajat Dhar et al.   Neurocritical Care

Sphingosine-1-Phosphate Receptor-2 Antagonists: Therapeutic Potential and Potential Risks

(2016) Kira V. Blankenbach et al.   Frontiers in Pharmacology

Capturing the Direct Binding of CFTR Correctors to CFTR by Using Click Chemistry

(2015) Chandrima Sinha et al.   CHEMBIOCHEM

Predictors and impact of early cerebral infarction after aneurysmal subarachnoid hemorrhage

(2015) R. Jabbarli et al.   EUROPEAN JOURNAL OF NEUROLOGY

Infection risk associated with anti-TNF-α agents: a review

(2015) Giuseppe Murdaca et al.   Expert Opinion On Drug Safety

Effect of Endothelin Receptor Antagonists on Clinically Relevant Outcomes after Experimental Subarachnoid Hemorrhage: A Systematic Review and Meta-Analysis

(2015) Kamil G Laban et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

20-HETE is Associated with Unfavorable Outcomes in Subarachnoid Hemorrhage Patients

(2015) Mark K Donnelly et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Neurovascular coupling in humans: Physiology, methodological advances and clinical implications

(2015) Aaron A Phillips et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Protective role of fingolimod (FTY720) in rats subjected to subarachnoid hemorrhage

(2015) Hao-Liang Xu et al.   Journal of Neuroinflammation

Cystic fibrosis transmembrane conductance regulator is involved in polyphenol-induced swelling of the endothelial glycocalyx

(2015) Wladimir Peters et al.   Nanomedicine-Nanotechnology Biology and Medicine

Lumacaftor–Ivacaftor in Patients with Cystic Fibrosis Homozygous for Phe508del CFTR

(2015) Claire E. Wainwright et al.   NEW ENGLAND JOURNAL OF MEDICINE

Are We Barking Up the Wrong Vessels?

(2015) Nicole Angela Terpolilli et al.   STROKE

Therapeutically Targeting Tumor Necrosis Factor-α/Sphingosine-1-Phosphate Signaling Corrects Myogenic Reactivity in Subarachnoid Hemorrhage

(2015) Kenji Yagi et al.   STROKE

Endogenous Events Modulating Myogenic Regulation of Cerebrovascular Function

(2014) Debebe Gebremedhin et al.   Current Vascular Pharmacology

Investigation of the Neuroprotective Impact of Nimodipine on Neuro2a Cells by Means of a Surgery-Like Stress Model

(2014) Eva Herzfeld et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The detrimental clinical impact of severe angiographic vasospasm may be diminished by maximal medical therapy and intensive endovascular treatment

(2014) Alex Mark Mortimer et al.   Journal of NeuroInterventional Surgery

Etanercept Alleviates Early Brain Injury Following Experimental Subarachnoid Hemorrhage and the Possible Role of Tumor Necrosis Factor-α and c-Jun N-Terminal Kinase Pathway

(2014) Bin-fei Zhang et al.   NEUROCHEMICAL RESEARCH

Protective Role of P450 Epoxyeicosanoids in Subarachnoid Hemorrhage

(2014) Dominic A. Siler et al.   Neurocritical Care

Subarachnoid Hemorrhage: a Review of Experimental Studies on the Microcirculation and the Neurovascular Unit

(2014) Michael K. Tso et al.   Translational Stroke Research

The Role of Arterioles and the Microcirculation in the Development of Vasospasm after Aneurysmal SAH

(2014) Masato Naraoka et al.   Biomed Research International

Fingolimod for the Treatment of Intracerebral Hemorrhage

(2014) Ying Fu et al.   JAMA Neurology

A CFTR corrector (lumacaftor) and a CFTR potentiator (ivacaftor) for treatment of patients with cystic fibrosis who have a phe508del CFTR mutation: a phase 2 randomised controlled trial

(2014) Michael P Boyle et al.   Lancet Respiratory Medicine

Second generation S1P pathway modulators: Research strategies and clinical developments

(2013) Marc Bigaud et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Impaired endothelial function after aneurysmal subarachnoid haemorrhage correlates with arginine:asymmetric dimethylarginine ratio † †This article is accompanied by Editorial I.

(2013) A. Bergström et al.   BRITISH JOURNAL OF ANAESTHESIA

20-HETE and Blood Pressure Regulation

(2013) Cheng-Chia Wu et al.   Cardiology in Review

The TNF-a/Sphingosine-1-Phosphate Signaling Axis Drives Myogenic Responsiveness in Heart Failure

(2013) Jeffrey T. Kroetsch et al.   JOURNAL OF VASCULAR RESEARCH

Delayed neurological deterioration after subarachnoid haemorrhage

(2013) R. Loch Macdonald   Nature Reviews Neurology

Clinical relevance of cerebral autoregulation following subarachnoid haemorrhage

(2013) Karol P. Budohoski et al.   Nature Reviews Neurology

Cl− channels in smooth muscle cells

(2013) Simon Bulley et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Nicardipine in the treatment of aneurysmal subarachnoid haemorrhage: a meta-analysis of published data

(2012) Ren-qiang Huang et al.   ACTA NEUROLOGICA BELGICA

Effect of intraarterial papaverine or nimodipine on vessel diameter in patients with cerebral vasospasm after subarachnoid hemorrhage

(2012) Thomas Kerz et al.   BRITISH JOURNAL OF NEUROSURGERY

Capitalizing on diversity: an integrative approach towards the multiplicity of cellular mechanisms underlying myogenic responsiveness

(2012) Darcy Lidington et al.   CARDIOVASCULAR RESEARCH

Ivacaftor in Subjects With Cystic Fibrosis Who Are Homozygous for the F508del-CFTR Mutation

(2012) Patrick A. Flume et al.   CHEST

Tumor Necrosis Factor-α–Mediated Downregulation of the Cystic Fibrosis Transmembrane Conductance Regulator Drives Pathological Sphingosine-1-Phosphate Signaling in a Mouse Model of Heart Failure

(2012) Anja Meissner et al.   CIRCULATION

Proximal Cerebral Arteries Develop Myogenic Responsiveness in Heart Failure via Tumor Necrosis Factor-α–Dependent Activation of Sphingosine-1-Phosphate Signaling

(2012) Jingli Yang et al.   CIRCULATION

Meta-Analysis of the Effectiveness and Safety of Prophylactic Use of Nimodipine in Patients with an Aneurysmal Subarachnoid Haemorrhage

(2012) Guang Jian Liu et al.   CNS & Neurological Disorders-Drug Targets

Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Potentiator VX-770 (Ivacaftor) Opens the Defective Channel Gate of Mutant CFTR in a Phosphorylation-dependent but ATP-independent Manner

(2012) Paul D. W. Eckford et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Vascular KCNQ (Kv7) Potassium Channels as Common Signaling Intermediates and Therapeutic Targets in Cerebral Vasospasm

(2012) Bharath K. Mani et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Prophylactic magnesium for improving neurologic outcome after aneurysmal subarachnoid hemorrhage: Systematic review and meta-analysis

(2012) Eyal Golan et al.   JOURNAL OF CRITICAL CARE

CFTR: An ion channel with a transporter-type energy-coupling mechanism: Figure 1.

(2012) Ming-Feng Tsai   JOURNAL OF GENERAL PHYSIOLOGY

Magnesium for aneurysmal subarachnoid haemorrhage (MASH-2): a randomised placebo-controlled trial

(2012) Sanne M Dorhout Mees et al.   LANCET

Ivacaftor

(2012) Pamela B. Davis et al.   NATURE REVIEWS DRUG DISCOVERY

The Role of Sphingosine Kinase 1/Sphingosine-1-Phosphate Pathway in the Myogenic Tone of Posterior Cerebral Arteries

(2012) Mihwa Lim et al.   PLoS One

Randomized Trial of Clazosentan in Patients With Aneurysmal Subarachnoid Hemorrhage Undergoing Endovascular Coiling

(2012) R. Loch Macdonald et al.   STROKE

Clinical Significance of Impaired Cerebrovascular Autoregulation After Severe Aneurysmal Subarachnoid Hemorrhage

(2012) Matthias Jaeger et al.   STROKE

Relationship Between Angiographic Vasospasm and Regional Hypoperfusion in Aneurysmal Subarachnoid Hemorrhage

(2012) Rajat Dhar et al.   STROKE

Guidelines for the Management of Aneurysmal Subarachnoid Hemorrhage

(2012) E. Sander Connolly et al.   STROKE

Targeting F508del-CFTR to develop rational new therapies for cystic fibrosis

(2011) Zhi-wei Cai et al.   ACTA PHARMACOLOGICA SINICA

The neurovascular unit in brain function and disease

(2011) C. Lecrux et al.   Acta Physiologica

Pressure-induced myogenic tone and role of 20-HETE in mediating autoregulation of cerebral blood flow

(2011) David R. Harder et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Role of myosin light chain kinase and myosin light chain phosphatase in the resistance arterial myogenic response to intravascular pressure

(2011) William C. Cole et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Cytochrome P450 eicosanoids and cerebral vascular function

(2011) John D. Imig et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Metoprolol impairs resistance artery function in mice

(2011) Mostafa H. El Beheiry et al.   JOURNAL OF APPLIED PHYSIOLOGY

Effect of pharmaceutical treatment on vasospasm, delayed cerebral ischemia, and clinical outcome in patients with aneurysmal subarachnoid hemorrhage: A systematic review and meta-analysis

(2011) Nima Etminan et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Pharmacological therapy for cystic fibrosis: From bench to bedside

(2011) Frédéric Becq et al.   Journal of Cystic Fibrosis

Clazosentan, an endothelin receptor antagonist, in patients with aneurysmal subarachnoid haemorrhage undergoing surgical clipping: a randomised, double-blind, placebo-controlled phase 3 trial (CONSCIOUS-2)

(2011) R Loch Macdonald et al.   LANCET NEUROLOGY

Perspective: Physiological Role(s) of the Vascular Myogenic Response

(2011) MICHAEL J. DAVIS   MICROCIRCULATION

Cerebrospinal Fluid 20-HETE Is Associated With Delayed Cerebral Ischemia and Poor Outcomes After Aneurysmal Subarachnoid Hemorrhage

(2011) Elizabeth A. Crago et al.   STROKE

Cerebral Infarction After Subarachnoid Hemorrhage Contributes to Poor Outcome by Vasospasm-Dependent and -Independent Effects

(2011) Mervyn D.I. Vergouwen et al.   STROKE

Vasospasm After Aneurysmal Subarachnoid Hemorrhage: Review of Randomized Controlled Trials and Meta-Analyses in the Literature

(2011) Gregory J. Velat et al.   World Neurosurgery

Fundamental increase in pressure-dependent constriction of brain parenchymal arterioles from subarachnoid hemorrhage model rats due to membrane depolarization

(2010) Matthew A. Nystoriak et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Relationship between brain interstitial fluid tumor necrosis factor-α and cerebral vasospasm after aneurysmal subarachnoid hemorrhage

(2010) Khalid A. Hanafy et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Pressure-dependent contribution of Rho kinase-mediated calcium sensitization in serotonin-evoked vasoconstriction of rat cerebral arteries

(2010) Ahmed F. El-Yazbi et al.   JOURNAL OF PHYSIOLOGY-LONDON

Participation ofKCNQ(Kv7) potassium channels in myogenic control of cerebral arterial diameter

(2010) Xi Zoë Zhong et al.   JOURNAL OF PHYSIOLOGY-LONDON

Proteomic Biomarker Discovery in Cerebrospinal Fluid for Cerebral Vasospasm Following Subarachnoid Hemorrhage

(2010) Shivanand P. Lad et al.   Journal of Stroke & Cerebrovascular Diseases

Brain interstitial fluid TNF-α after subarachnoid hemorrhage

(2010) Khalid A. Hanafy et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Sphingosine 1-Phosphate (S1P) Regulates Vascular Contraction via S1P3 Receptor: Investigation Based on a New S1P3 Receptor Antagonist

(2010) A. Murakami et al.   MOLECULAR PHARMACOLOGY

Current Practices of Triple-H Prophylaxis and Therapy in Patients with Subarachnoid Hemorrhage

(2010) Rachel Meyer et al.   Neurocritical Care

Vessel-specific role of sphingosine kinase 1 in the vasoconstriction of isolated basilar arteries

(2010) Salvatore Salomone et al.   PHARMACOLOGICAL RESEARCH

Definition of Delayed Cerebral Ischemia After Aneurysmal Subarachnoid Hemorrhage as an Outcome Event in Clinical Trials and Observational Studies

(2010) Mervyn D.I. Vergouwen et al.   STROKE

AMP-activated protein kinase and nitric oxide regulate the glucose sensitivity of ventromedial hypothalamic glucose-inhibited neurons

(2009) Beth Ann Murphy et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The Phosphorylation Motif at Serine 225 Governs the Localization and Function of Sphingosine Kinase 1 in Resistance Arteries

(2009) Darcy Lidington et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Protective Importance of the Myogenic Response in the Renal Circulation

(2009) Anil K. Bidani et al.   HYPERTENSION

Tumor Necrosis Factor-α Mediates Hemolysis-Induced Vasoconstriction and the Cerebral Vasospasm Evoked by Subarachnoid Hemorrhage

(2009) Carmine Vecchione et al.   HYPERTENSION

Expression and Distribution of Cystic Fibrosis Transmembrane Conductance Regulator in Neurons of the Human Brain

(2009) Yong Guo et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Impairment of intracerebral arteriole dilation responses after subarachnoid hemorrhage

(2009) Ik-Seong Park et al.   JOURNAL OF NEUROSURGERY

Acute Hypoperfusion Immediately after Subarachnoid Hemorrhage: A Xenon Contrast-Enhanced CT Study

(2009) Gerrit Alexander Schubert et al.   JOURNAL OF NEUROTRAUMA

Ca2+sensitization via phosphorylation of myosin phosphatase targeting subunit at threonine-855 by Rho kinase contributes to the arterial myogenic response

(2009) Rosalyn P. Johnson et al.   JOURNAL OF PHYSIOLOGY-LONDON

Rescue of CF airway epithelial cell function in vitro by a CFTR potentiator, VX-770

(2009) F. Van Goor et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Update of the Stroke Therapy Academic Industry Roundtable Preclinical Recommendations

(2009) Marc Fisher et al.   STROKE

Near-complete resolution of angiographic cerebral vasospasm after extreme elevation of mean arterial pressure: case report

(2009) Wilson Z. Ray et al.   SURGICAL NEUROLOGY

Therapeutic potential of pharmacologically targeting arteriolar myogenic tone

(2009) Michael A. Hill et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Extracellular matrix-specific focal adhesions in vascular smooth muscle produce mechanically active adhesion sites

(2008) Zhe Sun et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

CFTR in a lipid raft-TNFR1 complex modulates gap junctional intercellular communication and IL-8 secretion

(2008) Tecla Dudez et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Role of Sphingosine-1-Phosphate Phosphohydrolase 1 in the Regulation of Resistance Artery Tone

(2008) Bernhard Friedrich Peter et al.   CIRCULATION RESEARCH

STIM, ORAI AND TRPC CHANNELS IN THE CONTROL OF CALCIUM ENTRY SIGNALS IN SMOOTH MUSCLE

(2008) Youjun Wang et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Gq-coupled receptors as mechanosensors mediating myogenic vasoconstriction

(2008) Michael Mederos y Schnitzler et al.   EMBO JOURNAL

Preserved BK Channel Function in Vasospastic Myocytes from a Dog Model of Subarachnoid Hemorrhage

(2008) Babak S. Jahromi et al.   JOURNAL OF VASCULAR RESEARCH

Assessment of the CFTR and ENaC association

(2008) Bakhrom K. Berdiev et al.   Molecular BioSystems

Adapting Proteostasis for Disease Intervention

(2008) William E. Balch et al.   SCIENCE

Effect of Prophylactic Transluminal Balloon Angioplasty on Cerebral Vasospasm and Outcome in Patients With Fisher Grade III Subarachnoid Hemorrhage

(2008) Marike Zwienenberg-Lee et al.   STROKE

Clazosentan to Overcome Neurological Ischemia and Infarction Occurring After Subarachnoid Hemorrhage (CONSCIOUS-1)

(2008) R. Loch Macdonald et al.   STROKE

The effects induced by the sulphonylurea glibenclamide on the neonatal rat spinal cord indicate a novel mechanism to control neuronal excitability and inhibitory neurotransmission

(2006) K Ostroumov et al.   BRITISH JOURNAL OF PHARMACOLOGY