Protective role of fingolimod (FTY720) in rats subjected to subarachnoid hemorrhage

Pharmacologic blockade of vascular adhesion protein-1 lessens neurologic dysfunction in rats subjected to subarachnoid hemorrhage

(2014) Hao-Liang Xu et al.   BRAIN RESEARCH

Neurogenesis and Inflammation after Ischemic Stroke: What is Known and Where We Go from Here

(2014) Matthew K Tobin et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The rodent endovascular puncture model of subarachnoid hemorrhage: mechanisms of brain damage and therapeutic strategies

(2014) Elke Kooijman et al.   Journal of Neuroinflammation

Active, phosphorylated fingolimod inhibits histone deacetylases and facilitates fear extinction memory

(2014) Nitai C Hait et al.   NATURE NEUROSCIENCE

Long-Term Functional Consequences and Ongoing Cerebral Inflammation after Subarachnoid Hemorrhage in the Rat

(2014) Elke Kooijman et al.   PLoS One

Impact of an immune modulator fingolimod on acute ischemic stroke

(2014) Ying Fu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fingolimod for the treatment of neurological diseases—state of play and future perspectives

(2014) Robert Brunkhorst et al.   Frontiers in Cellular Neuroscience

Fingolimod for the Treatment of Intracerebral Hemorrhage

(2014) Ying Fu et al.   JAMA Neurology

The Role of the Microcirculation in Delayed Cerebral Ischemia and Chronic Degenerative Changes after Subarachnoid Hemorrhage

(2013) Leif Østergaard et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Delayed neurological deterioration after subarachnoid haemorrhage

(2013) R. Loch Macdonald   Nature Reviews Neurology

Fingolimod Reduces Hemorrhagic Transformation Associated With Delayed Tissue Plasminogen Activator Treatment in a Mouse Thromboembolic Model

(2013) Francisco Campos et al.   STROKE

SAHIT Investigators—on the Outcome of Some Subarachnoid Hemorrhage Clinical Trials

(2013) R. Loch Macdonald et al.   Translational Stroke Research

Role of the Sphingosine Metabolism Pathway on Neurons Against Experimental Cerebral Ischemia in Rats

(2013) Yu Hasegawa et al.   Translational Stroke Research

Fingolimod reduces cerebral lymphocyte infiltration in experimental models of rodent intracerebral hemorrhage

(2012) William B. Rolland et al.   EXPERIMENTAL NEUROLOGY

Functional analysis of Pro-inflammatory properties within the cerebrospinal fluid after subarachnoid hemorrhage in vivo and in vitro

(2012) Ulf C Schneider et al.   Journal of Neuroinflammation

Inflammation as a predictor for delayed cerebral ischemia after aneurysmal subarachnoid haemorrhage

(2012) Catherine J McMahon et al.   Journal of NeuroInterventional Surgery

The immunology of acute stroke

(2012) Ángel Chamorro et al.   Nature Reviews Neurology

Experimental Subarachnoid Hemorrhage Causes Early and Long-Lasting Microarterial Constriction and Microthrombosis: An in-vivo Microscopy Study

(2011) Benjamin Friedrich et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The immunology of stroke: from mechanisms to translation

(2011) Costantino Iadecola et al.   NATURE MEDICINE

The neurobiology of sphingosine 1-phosphate signaling and sphingosine 1-phosphate receptor modulators

(2011) B. Soliven et al.   NEUROLOGY

FTY720 Reduces Post-Ischemic Brain Lymphocyte Influx but Does Not Improve Outcome in Permanent Murine Cerebral Ischemia

(2011) Arthur Liesz et al.   PLoS One

Fingolimod provides long-term protection in rodent models of cerebral ischemia

(2010) Ying Wei et al.   ANNALS OF NEUROLOGY

Association of Platelet and Leukocyte Counts with Delayed Cerebral Ischemia in Aneurysmal Subarachnoid Hemorrhage

(2010) K.M. Kasius et al.   CEREBROVASCULAR DISEASES

Mechanism of Action of Oral Fingolimod (FTY720) in Multiple Sclerosis

(2010) Jerold Chun et al.   CLINICAL NEUROPHARMACOLOGY

Proteomic Biomarker Discovery in Cerebrospinal Fluid for Cerebral Vasospasm Following Subarachnoid Hemorrhage

(2010) Shivanand P. Lad et al.   Journal of Stroke & Cerebrovascular Diseases

Fingolimod (FTY720): discovery and development of an oral drug to treat multiple sclerosis

(2010) Volker Brinkmann et al.   NATURE REVIEWS DRUG DISCOVERY

Inflammation and Cerebral Vasospasm After Subarachnoid Hemorrhage

(2010) Gustavo Pradilla et al.   NEUROSURGERY CLINICS OF NORTH AMERICA

Immunodepression After Aneurysmal Subarachnoid Hemorrhage

(2010) Asita Sarrafzadeh et al.   STROKE

Randomized, double-blind, placebo-controlled, pilot trial of high-dose methylprednisolone in aneurysmal subarachnoid hemorrhage

(2009) Philippe Gomis et al.   JOURNAL OF NEUROSURGERY

Global variation in stroke burden and mortality: estimates from monitoring, surveillance, and modelling

(2009) S Claiborne Johnston et al.   LANCET NEUROLOGY

Activation of Sphingosine 1-Phosphate Receptor-1 by FTY720 Is Neuroprotective After Ischemic Stroke in Rats

(2009) Yu Hasegawa et al.   STROKE

Role of inflammation (leukocyte-endothelial cell interactions) in vasospasm after subarachnoid hemorrhage

(2009) Kaisorn L. Chaichana et al.   World Neurosurgery

Dynamic Alterations of Cerebral Pial Microcirculation During Experimental Subarachnoid Hemorrhage

(2008) Bao-Liang Sun et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

A new grading system evaluating bleeding scale in filament perforation subarachnoid hemorrhage rat model

(2007) Takashi Sugawara et al.   JOURNAL OF NEUROSCIENCE METHODS