TCL1targetingmiR-3676is codeleted with tumor protein p53 in chronic lymphocytic leukemia

Validation of ZAP-70 methylation and its relative significance in predicting outcome in chronic lymphocytic leukemia

(2014) R. Claus et al.   BLOOD

Chronic lymphocytic leukemia: 2013 update on diagnosis, risk stratification and treatment

(2013) Michael Hallek   AMERICAN JOURNAL OF HEMATOLOGY

Loss of p53 and altered miR15-a/16-1→MCL-1 pathway in CLL: insights from TCL1-Tg:p53 −/− mouse model and primary human leukemia cells

(2013) J Liu et al.   LEUKEMIA

Defective DROSHA processing contributes to downregulation of MiR-15/-16 in chronic lymphocytic leukemia

(2013) D Allegra et al.   LEUKEMIA

B cell receptor signaling in chronic lymphocytic leukemia

(2013) Jan A. Burger et al.   TRENDS IN IMMUNOLOGY

High-resolution genomic profiling of chronic lymphocytic leukemia reveals new recurrent genomic alterations

(2012) J. Edelmann et al.   BLOOD

Novel Insights in Molecular Mechanisms of CLL

(2012) Nicola Zanesi et al.   CURRENT PHARMACEUTICAL DESIGN

Quantitative DNA Methylation Analysis Identifies a Single CpG Dinucleotide Important for ZAP-70 Expression and Predictive of Prognosis in Chronic Lymphocytic Leukemia

(2012) Rainer Claus et al.   JOURNAL OF CLINICAL ONCOLOGY

Tcl1 protein functions as an inhibitor of de novo DNA methylation in B-cell chronic lymphocytic leukemia (CLL)

(2012) A. Palamarchuk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Bruton tyrosine kinase inhibitor PCI-32765 thwarts chronic lymphocytic leukemia cell survival and tissue homing in vitro and in vivo

(2011) S. Ponader et al.   BLOOD

miR-181b is a biomarker of disease progression in chronic lymphocytic leukemia

(2011) R. Visone et al.   BLOOD

Discovery of Novel Human Breast Cancer MicroRNAs from Deep Sequencing Data by Analysis of Pri-MicroRNA Secondary Structures

(2011) Seongho Ryu et al.   PLoS One

Understanding and Managing Ultra High-Risk Chronic Lymphocytic Leukemia

(2011) S. Stilgenbauer et al.   Hematology-American Society of Hematology Education Program

HS1 has a central role in the trafficking and homing of leukemic B cells

(2010) C. Scielzo et al.   BLOOD

Defining the RNA polymerase III transcriptome: Genome-wide localization of the RNA polymerase III transcription machinery in human cells

(2010) D. Canella et al.   GENOME RESEARCH

CD5+CD23+ leukemic cell populations in TCL1 transgenic mice show significantly increased proliferation and Akt phosphorylation

(2010) A Efanov et al.   LEUKEMIA

Chronic lymphocytic leukemia modeled in mouse by targeted miR-29 expression

(2010) U. Santanam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human tRNA-derived small RNAs in the global regulation of RNA silencing

(2010) D. Haussecker et al.   RNA

Molecular basis of CLL

(2010) Yuri Pekarsky et al.   SEMINARS IN CANCER BIOLOGY

Chronic lymphocytic leukemia of E -TCL1 transgenic mice undergoes rapid cell turnover that can be offset by extrinsic CD257 to accelerate disease progression

(2009) T. Enzler et al.   BLOOD

Transcription termination by nuclear RNA polymerases

(2009) P. Richard et al.   GENES & DEVELOPMENT

A novel class of small RNAs: tRNA-derived RNA fragments (tRFs)

(2009) Yong Sun Lee et al.   GENES & DEVELOPMENT

Chromatin structure analyses identify miRNA promoters

(2008) F. Ozsolak et al.   GENES & DEVELOPMENT

Whole-Genome Scanning by Array Comparative Genomic Hybridization as a Clinical Tool for Risk Assessment in Chronic Lymphocytic Leukemia

(2008) Shelly R. Gunn et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

MiR-15a and miR-16-1 cluster functions in human leukemia

(2008) George A. Calin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tcl1 functions as a transcriptional regulator and is directly involved in the pathogenesis of CLL

(2008) Y. Pekarsky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA