Estrogens and androgens inhibit association of RANKL with the pre-osteoblast membrane through post-translational mechanisms

Estrogens and Androgens in Skeletal Physiology and Pathophysiology

(2017) Maria Almeida et al.   PHYSIOLOGICAL REVIEWS

RANKL (Receptor Activator of NFκB Ligand) Produced by Osteocytes Is Required for the Increase in B Cells and Bone Loss Caused by Estrogen Deficiency in Mice

(2016) Yuko Fujiwara et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Effects of Aging and Sex Steroid Deficiency on the Murine Skeleton Are Independent and Mechanistically Distinct

(2016) Serra Ucer et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Estrogens antagonize RUNX2-mediated osteoblast-driven osteoclastogenesis through regulating RANKL membrane association

(2015) Anthony Martin et al.   BONE

Ligand Accessibility and Bioactivity of a Hormone–Dendrimer Conjugate Depend on pH and pH History

(2015) Sung Hoon Kim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Differential Effects of RUNX2 on the Androgen Receptor in Prostate Cancer: Synergistic Stimulation of a Gene Set Exemplified by SNAI2 and Subsequent Invasiveness

(2014) G. H. Little et al.   CANCER RESEARCH

Sex Steroid Actions in Male Bone

(2014) Dirk Vanderschueren et al.   ENDOCRINE REVIEWS

OPG and sRANKL serum levels and incident hip fracture in postmenopausal Caucasian women in the Women's Health Initiative Observational Study

(2013) Andrea Z. LaCroix et al.   BONE

Glucocorticoids Antagonize RUNX2 During Osteoblast Differentiation in Cultures of ST2 Pluripotent Mesenchymal Cells

(2013) Theodora Koromila et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Non-Nuclear–Initiated Actions of the Estrogen Receptor Protect Cortical Bone Mass

(2013) Shoshana M. Bartell et al.   MOLECULAR ENDOCRINOLOGY

ERα signaling regulates MMP3 expression to induce FasL cleavage and osteoclast apoptosis

(2012) Alejandro J Garcia et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Estrogen receptor-α signaling in osteoblast progenitors stimulates cortical bone accrual

(2012) Maria Almeida et al.   JOURNAL OF CLINICAL INVESTIGATION

New insights into osteoclastogenic signaling mechanisms

(2012) Tomoki Nakashima et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Estrogen and the skeleton

(2012) Sundeep Khosla et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

A RANKL G278R mutation causing osteopetrosis identifies a functional amino acid essential for trimer assembly in RANKL and TNF

(2011) Eleni Douni et al.   HUMAN MOLECULAR GENETICS

Evidence for osteocyte regulation of bone homeostasis through RANKL expression

(2011) Tomoki Nakashima et al.   NATURE MEDICINE

Genome-wide Runx2 occupancy in prostate cancer cells suggests a role in regulating secretion

(2011) Gillian H. Little et al.   NUCLEIC ACIDS RESEARCH

Regulation of adult bone turnover by sex steroids

(2010) Baruch Frenkel et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Developmentally regulated inhibition of cell cycle progression by glucocorticoids through repression of cyclin a transcription in primary osteoblast cultures

(2010) Yankel Gabet et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Runx2 transcriptome of prostate cancer cells: insights into invasiveness and bone metastasis

(2010) Sanjeev K Baniwal et al.   Molecular Cancer

Vps33a Mediates RANKL Storage in Secretory Lysosomes in Osteoblastic Cells

(2009) Yoshiaki Kariya et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Repression of Runx2 by Androgen Receptor (AR) in Osteoblasts and Prostate Cancer Cells: AR Binds Runx2 and Abrogates Its Recruitment to DNA

(2009) Sanjeev K. Baniwal et al.   MOLECULAR ENDOCRINOLOGY

Estrogen protects bone by inducing Fas ligand in osteoblasts to regulate osteoclast survival

(2008) Susan A Krum et al.   EMBO JOURNAL

Receptor Activator of Nuclear Factor κB Ligand and Osteoprotegerin Regulation of Bone Remodeling in Health and Disease

(2008) Ann E. Kearns et al.   ENDOCRINE REVIEWS

Modulation of Runx2 Activity by Estrogen Receptor-α: Implications for Osteoporosis and Breast Cancer

(2008) Omar Khalid et al.   ENDOCRINOLOGY