Tumor-Targeting Salmonella typhimurium A1-R Sensitizes Melanoma With a BRAF-V600E Mutation to Vemurafenib in a Patient-Derived Orthotopic Xenograft (PDOX) Nude Mouse Model

Facilitating T Cell Infiltration in Tumor Microenvironment Overcomes Resistance to PD-L1 Blockade

(2016) Haidong Tang et al.   CANCER CELL

PD-L1 expression in cancer patients receiving anti PD-1/PD-L1 antibodies: A systematic review and meta-analysis

(2016) Sara Gandini et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Efficacy of Tumor-Targeting Salmonella A1-R on a Melanoma Patient-Derived Orthotopic Xenograft (PDOX) Nude-Mouse Model

(2016) Mako Yamamoto et al.   PLoS One

Intraperitoneal administration of tumor-targeting Salmonella typhimurium A1-R inhibits disseminated human ovarian cancer and extends survival in nude mice

(2015) Yasunori Matsumoto et al.   Oncotarget

Tumor-Targeting Salmonella typhimurium A1-R in Combination with Trastuzumab Eradicates HER-2-Positive Cervical Cancer Cells in Patient-Derived Mouse Models

(2015) Yukihiko Hiroshima et al.   PLoS One

Tumor-Targeting Salmonella typhimurium A1-R Arrests a Chemo-Resistant Patient Soft-Tissue Sarcoma in Nude Mice

(2015) Yukihiko Hiroshima et al.   PLoS One

Inhibition of spontaneous and experimental lung metastasis of soft-tissue sarcoma by tumor-targeting Salmonella typhimurium A1-R

(2015) Shinji Miwa et al.   Oncotarget

Efficacy of tumor-targeting Salmonella typhimurium A1-R in combination with anti-angiogenesis therapy on a pancreatic cancer patient-derived orthotopic xenograft (PDOX) and cell line mouse models

(2015) Yukihiko Hiroshima et al.   Oncotarget

Tumor-targetingSalmonella typhimuriumA1-R decoys quiescent cancer cells to cycle as visualized by FUCCI imaging and become sensitive to chemotherapy

(2014) Shuya Yano et al.   CELL CYCLE

Methods for the development of tumor-targeting bacteria

(2014) Robert M Hoffman et al.   Expert Opinion on Drug Discovery

Efficacy ofSalmonella typhimuriumA1-R Versus Chemotherapy on a Pancreatic Cancer Patient-Derived Orthotopic Xenograft (PDOX)

(2014) Yukihiko Hiroshima et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Southwest Oncology Group S0008: A Phase III Trial of High-Dose Interferon Alfa-2b Versus Cisplatin, Vinblastine, and Dacarbazine, Plus Interleukin-2 and Interferon in Patients With High-Risk Melanoma—An Intergroup Study of Cancer and Leukemia Group B, Children's Oncology Group, Eastern Cooperative Oncology Group, and Southwest Oncology Group

(2014) Lawrence E. Flaherty et al.   JOURNAL OF CLINICAL ONCOLOGY

Successful Fluorescence-Guided Surgery on Human Colon Cancer Patient-Derived Orthotopic Xenograft Mouse Models Using a Fluorophore-Conjugated Anti-CEA Antibody and a Portable Imaging System

(2014) Yukihiko Hiroshima et al.   Journal of Laparoendoscopic & Advanced Surgical Techniques

Selective efficacy of zoledronic acid on metastasis in a patient-derived orthotopic xenograph (PDOX) nude-mouse model of human pancreatic cancer

(2014) Yukihiko Hiroshima et al.   JOURNAL OF SURGICAL ONCOLOGY

Safety and efficacy of vemurafenib in BRAFV600E and BRAFV600K mutation-positive melanoma (BRIM-3): extended follow-up of a phase 3, randomised, open-label study

(2014) Grant A McArthur et al.   LANCET ONCOLOGY

Melanoma Resistance: A Bright Future for Academicians and a Challenge for Patient Advocates

(2014) Andrzej T. Slominski et al.   MAYO CLINIC PROCEEDINGS

Combined Vemurafenib and Cobimetinib in BRAF-Mutated Melanoma

(2014) James Larkin et al.   NEW ENGLAND JOURNAL OF MEDICINE

Metastatic Recurrence in a Pancreatic Cancer Patient Derived Orthotopic Xenograft (PDOX) Nude Mouse Model Is Inhibited by Neoadjuvant Chemotherapy in Combination with Fluorescence-Guided Surgery with an Anti-CA 19-9-Conjugated Fluorophore

(2014) Yukihiko Hiroshima et al.   PLoS One

Comparison of efficacy ofSalmonella typhimuriumA1-R and chemotherapy on stem-like and non-stem human pancreatic cancer cells

(2013) Yukihiko Hiroshima et al.   CELL CYCLE

Fluorescently labeled chimeric anti-CEA antibody improves detection and resection of human colon cancer in a patient-derived orthotopic xenograft (PDOX) nude mouse model

(2013) Cristina A. Metildi et al.   JOURNAL OF SURGICAL ONCOLOGY

Inhibition and eradication of human glioma with tumor-targetingSalmonella typhimuriumin an orthotopic nude-mouse model

(2012) Masashi Momiyama et al.   CELL CYCLE

Dabrafenib in BRAF-mutated metastatic melanoma: a multicentre, open-label, phase 3 randomised controlled trial

(2012) Axel Hauschild et al.   LANCET

Survival in BRAF V600–Mutant Advanced Melanoma Treated with Vemurafenib

(2012) Jeffrey A. Sosman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Systemic targeting of primary bone tumor and lung metastasis of high-grade osteosarcoma in nude mice with a tumor-selective strain ofSalmonella typhymurium

(2011) Katsuhiro Hayashi et al.   CELL CYCLE

The bulge area is the origin of nestin-expressing pluripotent stem cells of the hair follicle

(2011) Aisada Uchugonova et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Improved Survival with Vemurafenib in Melanoma with BRAF V600E Mutation

(2011) Paul B. Chapman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Vessel destruction by tumor-targetingSalmonella typhimuriumA1-R is enhanced by high tumor vascularity

(2010) Fang Liu et al.   CELL CYCLE

Targeted therapy of spinal cord glioma with a genetically modifiedSalmonella typhimurium

(2009) H. Kimura et al.   CELL PROLIFERATION

Cancer metastasis directly eradicated by targeted therapy with a modifiedSalmonella typhimurium

(2009) Katsuhiro Hayashi et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Monotherapy with a Tumor-Targeting Mutant of S. typhimurium Inhibits Liver Metastasis in a Mouse Model of Pancreatic Cancer

(2009) Clinton Yam et al.   JOURNAL OF SURGICAL RESEARCH