AAV delivery of GRP78/BiP promotes adaptation of human RPE cell to ER stress

Differential dynamics of the mammalian mRNA and protein expression response to misfolding stress

(2016) Z. Cheng et al.   Molecular Systems Biology

Limited ATF4 Expression in Degenerating Retinas with Ongoing ER Stress Promotes Photoreceptor Survival in a Mouse Model of Autosomal Dominant Retinitis Pigmentosa

(2016) Yogesh Bhootada et al.   PLoS One

HSPA5/Dna K May Be a Useful Target for Human Disease Therapies

(2015) Laurence Booth et al.   DNA AND CELL BIOLOGY

Role of the unfolded protein response, GRP78 and GRP94 in organ homeostasis

(2015) Genyuan Zhu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Endoplasmic reticulum stress and the unfolded protein responses in retinal degeneration

(2014) Sarah X. Zhang et al.   EXPERIMENTAL EYE RESEARCH

Retinal Gene Therapy Using Adeno-Associated Viral Vectors: Multiple Applications for a Small Virus

(2014) William W. Hauswirth   HUMAN GENE THERAPY

The Chaperone Grp78 in Protein Folding Disorders of the Nervous System

(2014) Julie A. Moreno et al.   NEUROCHEMICAL RESEARCH

Role of Unfolded Protein Response Dysregulation in Oxidative Injury of Retinal Pigment Epithelial Cells

(2013) Chen Chen et al.   ANTIOXIDANTS & REDOX SIGNALING

A sigma-1 receptor antagonist (NE-100) prevents tunicamycin-induced cell death via GRP78 induction in hippocampal cells

(2013) Yoko Ono et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Regulatory crosstalk within the mammalian unfolded protein response

(2013) Joseph W. Brewer   CELLULAR AND MOLECULAR LIFE SCIENCES

The cell stress machinery and retinal degeneration

(2013) Dimitra Athanasiou et al.   FEBS LETTERS

A Comprehensive Review of Retinal Gene Therapy

(2013) Shannon E Boye et al.   MOLECULAR THERAPY

Targeting the unfolded protein response in disease

(2013) Claudio Hetz et al.   NATURE REVIEWS DRUG DISCOVERY

Targeting the unfolded protein response in neurodegeneration: A new approach to therapy

(2013) Mark Halliday et al.   NEUROPHARMACOLOGY

Activation of the Cellular Unfolded Protein Response by Recombinant Adeno-Associated Virus Vectors

(2013) Balaji Balakrishnan et al.   PLoS One

Long-Term Rescue of Retinal Structure and Function by Rhodopsin RNA Replacement with a Single Adeno-Associated Viral Vector in P23H RHO Transgenic Mice

(2012) Haoyu Mao et al.   HUMAN GENE THERAPY

The impact of the unfolded protein response on human disease

(2012) Shiyu Wang et al.   JOURNAL OF CELL BIOLOGY

BiP prevents rod opsin aggregation

(2012) Dimitra Athanasiou et al.   MOLECULAR BIOLOGY OF THE CELL

A review of the mammalian unfolded protein response

(2011) Anirikh Chakrabarti et al.   BIOTECHNOLOGY AND BIOENGINEERING

LEDGF1-326 Decreases P23H and Wild Type Rhodopsin Aggregates and P23H Rhodopsin Mediated Cell Damage in Human Retinal Pigment Epithelial Cells

(2011) Rinku Baid et al.   PLoS One

Restoration of visual function in P23H rhodopsin transgenic rats by gene delivery of BiP/Grp78

(2010) M. S. Gorbatyuk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human Amniotic Fluid Promotes Retinal Pigmented Epithelial Cells' Trans-Differentiation into Rod Photoreceptors and Retinal Ganglion Cells

(2010) Shima Ghaderi et al.   STEM CELLS AND DEVELOPMENT

Induction of BiP, an ER-resident protein, prevents the neuronal death induced by transient forebrain ischemia in gerbil

(2008) Y. Oida et al.   BRAIN RESEARCH

Overexpression of endoplasmic reticulum-resident chaperone attenuates cardiomyocyte death induced by proteasome inhibition

(2008) H. Y. Fu et al.   CARDIOVASCULAR RESEARCH