BMP9/COX-2 axial mediates high phosphate-induced calcification in vascular smooth muscle cells via Wnt/β-catenin pathway

Alkaline phosphatase: a novel treatment target for cardiovascular disease in CKD

(2017) Mathias Haarhaus et al.   Nature Reviews Nephrology

Pathology of Human Coronary and Carotid Artery Atherosclerosis and Vascular Calcification in Diabetes MellitusHighlights

(2016) Kazuyuki Yahagi et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Secreted Frizzled-Related Protein 5 Attenuates High Phosphate-Induced Calcification in Vascular Smooth Muscle Cells by Inhibiting the Wnt/ß-Catenin Pathway

(2016) Dai Deng et al.   CALCIFIED TISSUE INTERNATIONAL

Predictive ability of the pooled cohort risk assessment for the incidence and progression of coronary artery calcification

(2016) Sungmin Ye et al.   CORONARY ARTERY DISEASE

Hepatic differentiation of human pluripotent stem cells on human liver progenitor HepaRG-derived acellular matrix

(2016) Liisa K. Kanninen et al.   EXPERIMENTAL CELL RESEARCH

RANKL promotes osteoblastic activity in vascular smooth muscle cells by upregulating endothelial BMP-2 release

(2016) Colin Davenport et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Aberrant activation of Wnt pathways in arteries associates with vascular calcification in chronic kidney disease

(2016) Jingyi Liu et al.   INTERNATIONAL UROLOGY AND NEPHROLOGY

High Phosphorus Level Leads to Aortic Calcification via β-Catenin in Chronic Kidney Disease

(2015) Li Yao et al.   AMERICAN JOURNAL OF NEPHROLOGY

Canonical Wnt signaling acts synergistically on BMP9-induced osteo/odontoblastic differentiation of stem cells of dental apical papilla (SCAPs)

(2015) Hongmei Zhang et al.   BIOMATERIALS

Inflammation: a culprit for vascular calcification in atherosclerosis and diabetes

(2015) L. Bessueille et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Vascular calcification: Mechanisms of vascular smooth muscle cell calcification

(2015) Jane A. Leopold   TRENDS IN CARDIOVASCULAR MEDICINE

The role of COX-2 in mediating the effect of PTEN on BMP9 induced osteogenic differentiation in mouse embryonic fibroblasts

(2014) Jun Huang et al.   BIOMATERIALS

Vascular Calcification in Chronic Kidney Disease is Induced by Bone Morphogenetic Protein-2 via a Mechanism Involving the Wnt/�-Catenin Pathway

(2014) Shu Rong et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

BMP-9 regulates the osteoblastic differentiation and calcification of vascular smooth muscle cells through an ALK1 mediated pathway

(2014) Dongxing Zhu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Magnesium Inhibits Wnt/β-Catenin Activity and Reverses the Osteogenic Transformation of Vascular Smooth Muscle Cells

(2014) Addy Montes de Oca et al.   PLoS One

BMP9 and COX-2 form an important regulatory loop in BMP9-induced osteogenic differentiation of mesenchymal stem cells

(2013) Jin-Hua Wang et al.   BONE

Dietary vitamin K and therapeutic warfarin alter the susceptibility to vascular calcification in experimental chronic kidney disease

(2013) Kristin M. McCabe et al.   KIDNEY INTERNATIONAL

Interleukin-24 attenuates β-glycerophosphate-induced calcification of vascular smooth muscle cells by inhibiting apoptosis, the expression of calcification and osteoblastic markers, and the Wnt/β-catenin pathway

(2012) Ki-Mo Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

BMP signaling in vascular diseases

(2012) Jie Cai et al.   FEBS LETTERS

TGF-β and BMP Signaling in Osteoblast Differentiation and Bone Formation

(2012) Guiqian Chen et al.   International Journal of Biological Sciences

Mechanistic Insights into Vascular Calcification in CKD

(2012) R. Shroff et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

P38 and ERK1/2 MAPKs Act in Opposition to Regulate BMP9-Induced Osteogenic Differentiation of Mesenchymal Progenitor Cells

(2012) Yingze Zhao et al.   PLoS One

Bone Morphogenetic Proteins: A critical review

(2010) Beth Bragdon et al.   CELLULAR SIGNALLING

Activation of Vascular Smooth Muscle Parathyroid Hormone Receptor Inhibits Wnt/β-Catenin Signaling and Aortic Fibrosis in Diabetic Arteriosclerosis

(2010) Su-Li Cheng et al.   CIRCULATION RESEARCH

TGFβ/BMP Type I Receptors ALK1 and ALK2 Are Essential for BMP9-induced Osteogenic Signaling in Mesenchymal Stem Cells

(2010) Jinyong Luo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bone Morphogenetic Protein 7 (BMP7) Gene Polymorphisms Are Associated With Inverse Relationships Between Vascular Calcification and BMD: The Diabetes Heart Study

(2009) Barry I Freedman et al.   JOURNAL OF BONE AND MINERAL RESEARCH

BMP-2 promotes phosphate uptake, phenotypic modulation, and calcification of human vascular smooth muscle cells

(2008) Xianwu Li et al.   ATHEROSCLEROSIS

Pharmacological treatment of heterotopic ossification following hip and acetabular surgery

(2008) Robert J Macfarlane et al.   EXPERT OPINION ON PHARMACOTHERAPY

Oxidative Stress Induces Vascular Calcification through Modulation of the Osteogenic Transcription Factor Runx2 by AKT Signaling

(2008) Chang Hyun Byon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY