Secreted Frizzled-Related Protein 5 Attenuates High Phosphate-Induced Calcification in Vascular Smooth Muscle Cells by Inhibiting the Wnt/ß-Catenin Pathway

High Phosphorus Level Leads to Aortic Calcification via β-Catenin in Chronic Kidney Disease

(2015) Li Yao et al.   AMERICAN JOURNAL OF NEPHROLOGY

Angiotensin II prevents calcification in vascular smooth muscle cells by enhancing magnesium influx

(2015) Carmen Herencia et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Secreted frizzled-related protein 5 (Sfrp5) decreases hepatic stellate cell activation and liver fibrosis

(2015) Norihiro Chatani et al.   LIVER INTERNATIONAL

Angiotensin II increases secreted frizzled-related protein 5 (sFRP5) expression through AT1 receptor/Rho/ROCK1/JNK signaling in cardiomyocytes

(2015) Xin Jin et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

The Addition of Vascular Calcification Scores to Traditional Risk Factors Improves Cardiovascular Risk Assessment in Patients with Chronic Kidney Disease

(2015) Sophie Liabeuf et al.   PLoS One

Low serum level of secreted frizzled-related protein 5, an anti-inflammatory adipokine, is associated with coronary artery disease

(2014) Toru Miyoshi et al.   ATHEROSCLEROSIS

Vascular Calcification in Chronic Kidney Disease is Induced by Bone Morphogenetic Protein-2 via a Mechanism Involving the Wnt/�-Catenin Pathway

(2014) Shu Rong et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Vascular Calcification in Chronic Kidney Disease: Role of Disordered Mineral Metabolism

(2014) Shyamal Palit et al.   CURRENT PHARMACEUTICAL DESIGN

SFRP5 acts as a mature adipocyte marker but not as a regulator in adipogenesis

(2014) Rui Wang et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Magnesium Inhibits Wnt/β-Catenin Activity and Reverses the Osteogenic Transformation of Vascular Smooth Muscle Cells

(2014) Addy Montes de Oca et al.   PLoS One

Effect of Sfrp5 on Cytokine Release and Insulin Action in Primary Human Adipocytes and Skeletal Muscle Cells

(2014) Maren Carstensen et al.   PLoS One

Sfrp5 Modulates Both Wnt and BMP Signaling and Regulates Gastrointestinal Organogensis in the Zebrafish, Danio rerio

(2013) Carsten Stuckenholz et al.   PLoS One

Interleukin-24 attenuates β-glycerophosphate-induced calcification of vascular smooth muscle cells by inhibiting apoptosis, the expression of calcification and osteoblastic markers, and the Wnt/β-catenin pathway

(2012) Ki-Mo Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Secreted frizzled-related protein 5 suppresses adipocyte mitochondrial metabolism through WNT inhibition

(2012) Hiroyuki Mori et al.   JOURNAL OF CLINICAL INVESTIGATION

Serum Levels of Phosphorus, Parathyroid Hormone, and Calcium and Risks of Death and Cardiovascular Disease in Individuals With Chronic Kidney Disease

(2011) Suetonia C. Palmer   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Sfrp5 Is an Anti-Inflammatory Adipokine That Modulates Metabolic Dysfunction in Obesity

(2010) N. Ouchi et al.   SCIENCE

High phosphorus diet induces vascular calcification, a related decrease in bone mass and changes in the aortic gene expression

(2009) Pablo Román-García et al.   BONE

Phosphate feeding induces arterial medial calcification in uremic mice: role of serum phosphorus, fibroblast growth factor-23, and osteopontin

(2009) Mohga M. El-Abbadi et al.   KIDNEY INTERNATIONAL

The emerging role of phosphate in vascular calcification

(2009) Cecilia M. Giachelli   KIDNEY INTERNATIONAL

BMP-2 promotes phosphate uptake, phenotypic modulation, and calcification of human vascular smooth muscle cells

(2008) Xianwu Li et al.   ATHEROSCLEROSIS

Sfrp5 coordinates foregut specification and morphogenesis by antagonizing both canonical and noncanonical Wnt11 signaling

(2008) Y. Li et al.   GENES & DEVELOPMENT

Beyond Wnt inhibition: new functions of secreted Frizzled-related proteins in development and disease

(2008) P. Bovolenta et al.   JOURNAL OF CELL SCIENCE

Mechanisms of Vascular Calcification in Chronic Kidney Disease

(2007) S. M. Moe et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY