Epigallocatechin gallate reverses cTnI-low expression-induced age-related heart diastolic dysfunction through histone acetylation modification

Diastolic dysfunction and cardiac troponin I decrease in aging hearts

(2016) B. Pan et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Mitochondrial dysfunction in cardiac aging

(2015) Autumn Tocchi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Molecular mechanism of endothelial and vascular aging: implications for cardiovascular disease

(2015) Giovanni G. Camici et al.   EUROPEAN HEART JOURNAL

Non-sirtuin histone deacetylases in the control of cardiac aging

(2015) Bradley S. Ferguson et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Alcohol Consumption During Gestation Causes Histone3 Lysine9 Hyperacetylation and an Alternation of Expression of Heart Development-Related Genes in Mice

(2014) Bo Pan et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Heart Failure With Preserved Ejection Fraction

(2014) Kavita Sharma et al.   CIRCULATION RESEARCH

Spironolactone for Heart Failure with Preserved Ejection Fraction

(2014) Bertram Pitt et al.   NEW ENGLAND JOURNAL OF MEDICINE

GATA-dependent regulatory switches establish atrioventricular canal specificity during heart development

(2014) Sonia Stefanovic et al.   Nature Communications

New insights into the mechanisms of polyphenols beyond antioxidant properties; lessons from the green tea polyphenol, epigallocatechin 3-gallate

(2014) Hae-Suk Kim et al.   Redox Biology

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

Dose-dependent diastolic dysfunction and early death in a mouse model with cardiac troponin mutations

(2013) Yuejin Li et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Cardiac Aging: From Molecular Mechanisms to Significance in Human Health and Disease

(2012) Dao-Fu Dai et al.   ANTIOXIDANTS & REDOX SIGNALING

Green tea polyphenols increase p53 transcriptional activity and acetylation by suppressing class�I histone deacetylases

(2012) Sanjay Gupta   INTERNATIONAL JOURNAL OF ONCOLOGY

(-)-Epigallocatechin-3-gallate reactivates silenced tumor suppressor genes, Cip1/p21 and p16INK4a, by reducing DNA methylation and increasing histones acetylation in human skin cancer cells

(2011) V. Nandakumar et al.   CARCINOGENESIS

Why are women more likely than men to develop heart failure with preserved ejection fraction?

(2011) Dawn C. Scantlebury et al.   CURRENT OPINION IN CARDIOLOGY

Progression of Left Ventricular Diastolic Dysfunction and Risk of Heart Failure

(2011) Garvan C. Kane et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Epigenetics in heart failure

(2010) Roberto Papait et al.   Annals of the New York Academy of Sciences

The antioxidant and pro-oxidant activities of green tea polyphenols: A role in cancer prevention

(2010) Joshua D. Lambert et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Heart failure with preserved ejection fraction: pathophysiology, diagnosis, and treatment

(2010) B. A. Borlaug et al.   EUROPEAN HEART JOURNAL

Synergistic epigenetic reactivation of estrogen receptor-alpha (ERalpha) by combined green tea polyphenol and histone deacetylase inhibitor in ERalpha-negative breast cancer cells

(2010) Yuanyuan Li et al.   Molecular Cancer

Promoter demethylation and chromatin remodeling by green tea polyphenols leads to re-expression of GSTP1 in human prostate cancer cells

(2009) Mitali Pandey et al.   INTERNATIONAL JOURNAL OF CANCER

Inhibition of class I histone deacetylase with an apicidin derivative prevents cardiac hypertrophy and failure

(2008) Pasquale Gallo et al.   CARDIOVASCULAR RESEARCH