Fibroblast growth factors in the management of spinal cord injury

Regulation of Caveolin-1 and Junction Proteins by bFGF Contributes to the Integrity of Blood–Spinal Cord Barrier and Functional Recovery

(2016) Li-Bing Ye et al.   Neurotherapeutics

Investigational drugs for the treatment of spinal cord injury: review of preclinical studies and evaluation of clinical trials from Phase I to II

(2015) Narihito Nagoshi et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

The Role of bFGF in the Excessive Activation of Astrocytes Is Related to the Inhibition of TLR4/NFκB Signals

(2015) Libing Ye et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Disruption of Fgf13 Causes Synaptic Excitatory-Inhibitory Imbalance and Genetic Epilepsy and Febrile Seizures Plus

(2015) R. S. Puranam et al.   JOURNAL OF NEUROSCIENCE

Acute Spinal Cord Injury

(2015) Christopher D. Witiw et al.   JOURNAL OF SPINAL DISORDERS & TECHNIQUES

Repair of spinal cord injury by implantation of bFGF-incorporated HEMA-MOETACL hydrogel in rats

(2015) Bo Chen et al.   Scientific Reports

Potential Role of Growth Factors in the Management of Spinal Cord Injury

(2015) Basem I. Awad et al.   World Neurosurgery

Research Advances in Tissue Engineering Materials for Sustained Release of Growth Factors

(2015) Hai-yang Zhao et al.   Biomed Research International

Physiological Functions and Underlying Mechanisms of Fibroblast Growth Factor (FGF) Family Members: Recent Findings and Implications for Their Pharmacological Application

(2014) Toru Imamura   BIOLOGICAL & PHARMACEUTICAL BULLETIN

SUN11602 has basic fibroblast growth factor-like activity and attenuates neuronal damage and cognitive deficits in a rat model of Alzheimer׳s disease induced by amyloid β and excitatory amino acids

(2014) Ryoko Ogino et al.   BRAIN RESEARCH

An Acute Growth Factor Treatment that Preserves Function after Spinal Cord Contusion Injury

(2014) Fatemeh Chehrehasa et al.   JOURNAL OF NEUROTRAUMA

Endoplasmic Reticulum Stress: Relevance and Therapeutics in Central Nervous System Diseases

(2014) Hong-Yu Zhang et al.   MOLECULAR NEUROBIOLOGY

Astrocyte activation is suppressed in both normal and injured brain by FGF signaling

(2014) W. Kang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Astrocyte infiltration into injectable collagen-based hydrogels containing FGF-2 to treat spinal cord injury

(2013) Daniel J. Macaya et al.   BIOMATERIALS

A Novel Growth-Promoting Pathway Formed by GDNF-Overexpressing Schwann Cells Promotes Propriospinal Axonal Regeneration, Synapse Formation, and Partial Recovery of Function after Spinal Cord Injury

(2013) L.-X. Deng et al.   JOURNAL OF NEUROSCIENCE

Spinal Cord Injury Facts and Figures at a Glance

(2013)   JOURNAL OF SPINAL CORD MEDICINE

Regulation of Autophagy and Ubiquitinated Protein Accumulation by bFGF Promotes Functional Recovery and Neural Protection in a Rat Model of Spinal Cord Injury

(2013) Hong-Yu Zhang et al.   MOLECULAR NEUROBIOLOGY

Basic fibroblast growth factor is a key factor that induces bone marrow mesenchymal stem cells towards cells with Schwann cell phenotype

(2013) Hui Zhu et al.   NEUROSCIENCE LETTERS

Roles of FGF20 in dopaminergic neurons and Parkinson's disease

(2013) Nobuyuki Itoh et al.   Frontiers in Molecular Neuroscience

SUN11602, a Novel Aniline Compound, Mimics the Neuroprotective Mechanisms of Basic Fibroblast Growth Factor

(2012) Norihito Murayama et al.   ACS Chemical Neuroscience

Direct FGF-2 Gene Transfer via Recombinant Adeno-Associated Virus Vectors Stimulates Cell Proliferation, Collagen Production, and the Repair of Experimental Lesions in the Human ACL

(2012) Henning Madry et al.   AMERICAN JOURNAL OF SPORTS MEDICINE

Fibroblast Growth Factor 13 Is a Microtubule-Stabilizing Protein Regulating Neuronal Polarization and Migration

(2012) Qing-Feng Wu et al.   CELL

Localized and Sustained Delivery of Fibroblast Growth Factor-2 from a Nanoparticle-Hydrogel Composite for Treatment of Spinal Cord Injury

(2012) Catherine E. Kang et al.   CELLS TISSUES ORGANS

Exogenous Basic Fibroblast Growth Factor Inhibits ER Stress-Induced Apoptosis and Improves Recovery from Spinal Cord Injury

(2012) Hong-Yu Zhang et al.   CNS Neuroscience & Therapeutics

Deletion of Endoplasmic Reticulum Stress-Induced CHOP Protects Microvasculature Post-Spinal Cord Injury

(2012) Janelle M. Fassbender et al.   CURRENT NEUROVASCULAR RESEARCH

Current stem cell treatments for spinal cord injury

(2012) MG Fehlings et al.   Indian Journal of Orthopaedics

Incidence and Prevalence of Spinal Cord Injury in Canada: A National Perspective

(2012) Vanessa K. Noonan et al.   NEUROEPIDEMIOLOGY

The Fibroblast Growth Factor Family: Neuromodulation of Affective Behavior

(2012) Cortney A. Turner et al.   NEURON

Fibroblast growth factor-20 protects against dopamine neuron loss in vitro and provides functional protection in the 6-hydroxydopamine-lesioned rat model of Parkinson's disease

(2012) Isobel J. Sleeman et al.   NEUROPHARMACOLOGY

Combination therapies in the CNS: Engineering the environment

(2012) Dylan A. McCreedy et al.   NEUROSCIENCE LETTERS

Recent therapeutic strategies for spinal cord injury treatment: possible role of stem cells

(2012) D. Garbossa et al.   NEUROSURGICAL REVIEW

Chondroitinase and Growth Factors Enhance Activation and Oligodendrocyte Differentiation of Endogenous Neural Precursor Cells after Spinal Cord Injury

(2012) Soheila Karimi-Abdolrezaee et al.   PLoS One

Roles of intracellular fibroblast growth factors in neural development and functions

(2012) Xu Zhang et al.   Science China-Life Sciences

bFGF inhibits ER stress induced by ischemic oxidative injury via activation of the PI3K/Akt and ERK1/2 pathways

(2012) Zhouguang Wang et al.   TOXICOLOGY LETTERS

Erratum: IFN-γ signaling, with the synergistic contribution of TNF-α, mediates cell specific microglial and astroglial activation in experimental models of Parkinson’s disease

(2012) C Barcia et al.   Cell Death & Disease

Acid Fibroblast Growth Factor and Peripheral Nerve Grafts Regulate Th2 Cytokine Expression, Macrophage Activation, Polyamine Synthesis, and Neurotrophin Expression in Transected Rat Spinal Cords

(2011) H.-S. Kuo et al.   JOURNAL OF NEUROSCIENCE

Acidic fibroblast growth factor for repair of human spinal cord injury: a clinical trial

(2011) Jau-Ching Wu et al.   JOURNAL OF NEUROSURGERY-SPINE

From Cradle to Grave: The Multiple Roles of Fibroblast Growth Factors in Neural Development

(2011) François Guillemot et al.   NEURON

Regulation of chondroitin sulphate proteoglycan and reactive gliosis after spinal cord transection: effects of peripheral nerve graft and fibroblast growth factor 1

(2011) M-J. Lee et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

JNK/ERK/FAK Mediate Promigratory Actions of Basic Fibroblast Growth Factor in Astrocytes via CCL2 and COX2

(2011) Mathieu P. Lichtenstein et al.   NEUROSIGNALS

Cellular Treatments for Spinal Cord Injury: The Time is Right for Clinical Trials

(2011) Michael G. Fehlings et al.   Neurotherapeutics

Adipose-Derived Stem Cells Stimulate Regeneration of Peripheral Nerves: BDNF Secreted by These Cells Promotes Nerve Healing and Axon Growth De Novo

(2011) Tatiana Lopatina et al.   PLoS One

Metabolic Activities and Chondrogenic Differentiation of Human Mesenchymal Stem Cells Following Recombinant Adeno-Associated Virus–Mediated Gene Transfer and Overexpression of Fibroblast Growth Factor 2

(2011) Magali Cucchiarini et al.   TISSUE ENGINEERING PART A

Acceleration of articular cartilage repair by combined gene transfer of human insulin-like growth factor I and fibroblast growth factor-2 in vivo

(2010) Henning Madry et al.   ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY

Implantation of adult bone marrow-derived mesenchymal stem cells transfected with the neurotrophin-3 gene and pretreated with retinoic acid in completely transected spinal cord

(2010) Wei Zhang et al.   BRAIN RESEARCH

Looking at the blood–brain barrier: Molecular anatomy and possible investigation approaches

(2010) Filipa Lourenço Cardoso et al.   BRAIN RESEARCH REVIEWS

Neuritogenic and Neuroprotective Properties of Peptide Agonists of the Fibroblast Growth Factor Receptor

(2010) Shizhong Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Transplantation of Ciliary Neurotrophic Factor-Expressing Adult Oligodendrocyte Precursor Cells Promotes Remyelination and Functional Recovery after SpinalCord Injury

(2010) Q. Cao et al.   JOURNAL OF NEUROSCIENCE

Concise Review: Bone Marrow for the Treatment of Spinal Cord Injury: Mechanisms and Clinical Applications

(2010) Karina T. Wright et al.   STEM CELLS

Fibroblast Growth Factors: Biology, Function, and Application for Tissue Regeneration

(2010) Ye-Rang Yun et al.   Journal of Tissue Engineering

Overcoming Macrophage-Mediated Axonal Dieback Following CNS Injury

(2009) S. A. Busch et al.   JOURNAL OF NEUROSCIENCE

BDNF-Hypersecreting Human Mesenchymal Stem Cells Promote Functional Recovery, Axonal Sprouting, and Protection of Corticospinal Neurons after Spinal Cord Injury

(2009) M. Sasaki et al.   JOURNAL OF NEUROSCIENCE

Identification of Two Distinct Macrophage Subsets with Divergent Effects Causing either Neurotoxicity or Regeneration in the Injured Mouse Spinal Cord

(2009) K. A. Kigerl et al.   JOURNAL OF NEUROSCIENCE

Control protocol for robust in vitro glial scar formation around microwires: Essential roles of bFGF and serum in gliosis

(2009) Vadim S. Polikov et al.   JOURNAL OF NEUROSCIENCE METHODS

Structure and function of the blood–brain barrier

(2009) N. Joan Abbott et al.   NEUROBIOLOGY OF DISEASE

Synergistic neuroprotective effect via simian lentiviral vector-mediated simultaneous gene transfer of human pigment epithelium-derived factor and human fibroblast growth factor-2 in rodent models of retinitis pigmentosa

(2008) Masanori Miyazaki et al.   JOURNAL OF GENE MEDICINE

Nerve repair using acidic fibroblast growth factor in human cervical spinal cord injury: a preliminary Phase I clinical study

(2008) Jau-Ching Wu et al.   JOURNAL OF NEUROSURGERY-SPINE

Pharmacological Neuroprotective Therapy for Acute Spinal Cord Injury: State of the Art

(2008) A. Ibarra et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Involvement of Acidic Fibroblast Growth Factor in Spinal Cord Injury Repair Processes Revealed by a Proteomics Approach

(2008) Ming-Chu Tsai et al.   MOLECULAR & CELLULAR PROTEOMICS

Combined treatment using peripheral nerve graft and FGF-1: Changes to the glial environment and differential macrophage reaction in a complete transected spinal cord

(2008) Meng-Jen Lee et al.   NEUROSCIENCE LETTERS