TRPC1 is a differential regulator of hypoxia-mediated events and Akt signalling in PTEN-deficient breast cancer cells

The hypoxic tumor microenvironment: A driving force for breast cancer progression

(2016) Gregg L. Semenza   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Plasma membrane ion channels and epithelial to mesenchymal transition in cancer cells

(2016) Iman Azimi et al.   ENDOCRINE-RELATED CANCER

STAT3 regulates hypoxia-induced epithelial mesenchymal transition in oesophageal squamous cell cancer

(2016) YAO CUI et al.   ONCOLOGY REPORTS

Hypoxia inducible factor-1-dependent up-regulation of BMP4 mediates hypoxia-induced increase of TRPC expression in PASMCs

(2015) Jian Wang et al.   CARDIOVASCULAR RESEARCH

EglN2 associates with the NRF1‐PGC1α complex and controls mitochondrial function in breast cancer

(2015) Jing Zhang et al.   EMBO JOURNAL

A background Ca2+entry pathway mediated by TRPC1/TRPC4 is critical for development of pathological cardiac remodelling

(2015) Juan E. Camacho Londoño et al.   EUROPEAN HEART JOURNAL

Altered purinergic receptor-Ca2+ signaling associated with hypoxia-induced epithelial-mesenchymal transition in breast cancer cells

(2015) Iman Azimi et al.   Molecular Oncology

Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance

(2015) Kari R. Fischer et al.   NATURE

Epithelial–Mesenchymal Plasticity: A Central Regulator of Cancer Progression

(2015) Xin Ye et al.   TRENDS IN CELL BIOLOGY

Comprehensive Genomic Analysis Identifies Novel Subtypes and Targets of Triple-Negative Breast Cancer

(2014) M. D. Burstein et al.   CLINICAL CANCER RESEARCH

TRPM2 channels mediate acetaminophen-induced liver damage

(2014) E. Kheradpezhouh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Essential role for TrpC5-containing extracellular vesicles in breast cancer with chemotherapeutic resistance

(2014) X. Ma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Classical Transient Receptor Potential Channel 1 in Hypoxia-induced Pulmonary Hypertension

(2013) Monika Malczyk et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Knockout of the Trpc1 gene reveals that TRPC1 can promote recovery from anaphylaxis by negatively regulating mast cell TNF-α production

(2013) Nevenka Medic et al.   CELL CALCIUM

Classical Transient Receptor Potential 1 and 6 Contribute to Hypoxic Pulmonary Hypertension Through Differential Regulation of Pulmonary Vascular Functions

(2013) Yang Xia et al.   HYPERTENSION

WEB-based GEne SeT AnaLysis Toolkit (WebGestalt): update 2013

(2013) Jing Wang et al.   NUCLEIC ACIDS RESEARCH

STAT3 and HIF1α cooperatively activate HIF1 target genes in MDA-MB-231 and RCC4 cells

(2013) M R Pawlus et al.   ONCOGENE

Induction of epithelial–mesenchymal transition (EMT) in breast cancer cells is calcium signal dependent

(2013) F M Davis et al.   ONCOGENE

mTOR-Controlled Autophagy Requires Intracellular Ca2+ Signaling

(2013) Jean-Paul Decuypere et al.   PLoS One

Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal

(2013) J. Gao et al.   Science Signaling

Calcium-permeable ion channels in control of autophagy and cancer

(2013) Artem Kondratskyi   Frontiers in Physiology

Pericyte Depletion Results in Hypoxia-Associated Epithelial-to-Mesenchymal Transition and Metastasis Mediated by Met Signaling Pathway

(2012) Vesselina G. Cooke et al.   CANCER CELL

Hypoxia-Induced Autophagy Promotes Tumor Cell Survival and Adaptation to Antiangiogenic Treatment in Glioblastoma

(2012) Y.-L. Hu et al.   CANCER RESEARCH

Role of the inositol 1,4,5-trisphosphate receptor/Ca2+-release channel in autophagy

(2012) Jan B Parys et al.   Cell Communication and Signaling

TRPC1 Protein Channel Is Major Regulator of Epidermal Growth Factor Receptor Signaling

(2012) Nicolas Tajeddine et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neurotoxin-induced ER stress in mouse dopaminergic neurons involves downregulation of TRPC1 and inhibition of AKT/mTOR signaling

(2012) Senthil Selvaraj et al.   JOURNAL OF CLINICAL INVESTIGATION

Gene disruption of the calcium channel Orai1 results in inhibition of osteoclast and osteoblast differentiation and impairs skeletal development

(2012) Lisa J Robinson et al.   LABORATORY INVESTIGATION

Comprehensive molecular portraits of human breast tumours

(2012) Daniel C. Koboldt et al.   NATURE

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

Cancer–stromal cell interactions mediated by hypoxia-inducible factors promote angiogenesis, lymphangiogenesis and metastasis

(2012) G L Semenza   ONCOGENE

Non-Stimulated, Agonist-Stimulated and Store-Operated Ca2+ Influx in MDA-MB-468 Breast Cancer Cells and the Effect of EGF-Induced EMT on Calcium Entry

(2012) Felicity M. Davis et al.   PLoS One

Hypoxia Activated EGFR Signaling Induces Epithelial to Mesenchymal Transition (EMT)

(2012) Ashish Misra et al.   PLoS One

Transient receptor potential channel TRPC5 is essential for P-glycoprotein induction in drug-resistant cancer cells

(2012) X. Ma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Calpain cleaves and activates the TRPC5 channel to participate in semaphorin 3A-induced neuronal growth cone collapse

(2012) J. S. Kaczmarek et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq

(2011) J. Schodel et al.   BLOOD

Genomic analysis identifies unique signatures predictive of brain, lung, and liver relapse

(2011) J. Chuck Harrell et al.   BREAST CANCER RESEARCH AND TREATMENT

ORAI1 Deficiency Impairs Activated T Cell Death and Enhances T Cell Survival

(2011) K.-D. Kim et al.   JOURNAL OF IMMUNOLOGY

Integrative genomics viewer

(2011) James T Robinson et al.   NATURE BIOTECHNOLOGY

Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression

(2011) Mina J Bissell et al.   NATURE MEDICINE

Subtype and pathway specific responses to anticancer compounds in breast cancer

(2011) L. M. Heiser et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Essential Regulation of Cell Bioenergetics by Constitutive InsP3 Receptor Ca2+ Transfer to Mitochondria

(2010) César Cárdenas et al.   CELL

Golgi Calcium Pump Secretory Pathway Calcium ATPase 1 (SPCA1) Is a Key Regulator of Insulin-like Growth Factor Receptor (IGF1R) Processing in the Basal-like Breast Cancer Cell Line MDA-MB-231

(2010) Desma M. Grice et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Novel Native Store-operated Calcium Channel Encoded by Orai3

(2010) Rajender K. Motiani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Epithelial Mesenchymal Transition Traits in Human Breast Cancer Cell Lines Parallel the CD44hi/CD24lo/- Stem Cell Phenotype in Human Breast Cancer

(2010) Tony Blick et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

Genome-wide identification of hypoxia-inducible factor binding sites and target genes by a probabilistic model integrating transcription-profiling data and in silico binding site prediction

(2010) Amaya Ortiz-Barahona et al.   NUCLEIC ACIDS RESEARCH

International Union of Basic and Clinical Pharmacology. LXXVI. Current Progress in the Mammalian TRP Ion Channel Family

(2010) L.-J. Wu et al.   PHARMACOLOGICAL REVIEWS

An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients

(2009) Balazs Györffy et al.   BREAST CANCER RESEARCH AND TREATMENT

Characterization of a Naturally Occurring Breast Cancer Subset Enriched in Epithelial-to-Mesenchymal Transition and Stem Cell Characteristics

(2009) B. T. Hennessy et al.   CANCER RESEARCH

Plasma membrane calcium ATPase 4 and the remodeling of calcium homeostasis in human colon cancer cells

(2009) Cho S. Aung et al.   CARCINOGENESIS

Essential Role for TRPC5 in Amygdala Function and Fear-Related Behavior

(2009) Antonio Riccio et al.   CELL

Hypoxia induces chemoresistance in ovarian cancer cells by activation of signal transducer and activator of transcription 3

(2009) Karuppaiyah Selvendiran et al.   INTERNATIONAL JOURNAL OF CANCER

Biology of HIF-1α

(2008) A Weidemann et al.   CELL DEATH AND DIFFERENTIATION

PIK3CA mutation occurs in nasopharyngeal carcinoma but does not significantly influence the disease-specific survival

(2008) Chu-Chung Chou et al.   MEDICAL ONCOLOGY