Integrin α8 and Pcdh15 act as a complex to regulate cilia biogenesis in sensory cells

Characterization of the ternary Usher syndrome SANS/ush2a/whirlin protein complex

(2017) Nasrin Sorusch et al.   HUMAN MOLECULAR GENETICS

Functional Analysis of the Transmembrane and Cytoplasmic Domains of Pcdh15a in Zebrafish Hair Cells

(2017) Reo Maeda et al.   JOURNAL OF NEUROSCIENCE

Mutations in CDC14A , Encoding a Protein Phosphatase Involved in Hair Cell Ciliogenesis, Cause Autosomal-Recessive Severe to Profound Deafness

(2016) Sedigheh Delmaghani et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Pharyngeal morphogenesis requires fras1 - itga8 -dependent epithelial-mesenchymal interaction

(2016) Jared Coffin Talbot et al.   DEVELOPMENTAL BIOLOGY

Primary cilia are not calcium-responsive mechanosensors

(2016) M. Delling et al.   NATURE

Reverse Genetic Screening Reveals Poor Correlation between Morpholino-Induced and Mutant Phenotypes in Zebrafish

(2015) Fatma O. Kok et al.   DEVELOPMENTAL CELL

Phosphoproteomic screening identifies Rab GTPases as novel downstream targets of PINK1

(2015) Y.-C. Lai et al.   EMBO JOURNAL

Impact of the Usher syndrome on olfaction

(2015) Fabian Jansen et al.   HUMAN MOLECULAR GENETICS

A missense mutation in DCDC2 causes human recessive deafness DFNB66, likely by interfering with sensory hair cell and supporting cell cilia length regulation

(2015) M'hamed Grati et al.   HUMAN MOLECULAR GENETICS

The Arf and Rab11 effector FIP3 acts synergistically with ASAP1 to direct Rabin8 in ciliary receptor targeting

(2015) J. Wang et al.   JOURNAL OF CELL SCIENCE

The Rho-specific GAP protein DLC3 coordinates endocytic membrane trafficking

(2015) A. C. Braun et al.   JOURNAL OF CELL SCIENCE

The centrosome is an actin-organizing centre

(2015) Francesca Farina et al.   NATURE CELL BIOLOGY

Mutations in TRAF3IP1/IFT54 reveal a new role for IFT proteins in microtubule stabilization

(2015) Albane A. Bizet et al.   Nature Communications

The Ciliopathy Protein CC2D2A Associates with NINL and Functions in RAB8-MICAL3-Regulated Vesicle Trafficking

(2015) Ruxandra Bachmann-Gagescu et al.   PLoS Genetics

Specialized Cilia in Mammalian Sensory Systems

(2015) Nathalie Falk et al.   Cells

Integrin Alpha 8 Recessive Mutations Are Responsible for Bilateral Renal Agenesis in Humans

(2014) Camille Humbert et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Clarin-1 acts as a modulator of mechanotransduction activity and presynaptic ribbon assembly

(2014) Oluwatobi Ogun et al.   JOURNAL OF CELL BIOLOGY

Tip-link protein protocadherin 15 interacts with transmembrane channel-like proteins TMC1 and TMC2

(2014) R. Maeda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Cellular and Physiological Functions of the Lowe Syndrome Protein OCRL1

(2014) Zenobia B. Mehta et al.   TRAFFIC

Photoreceptors in whirler mice show defective transducin translocation and are susceptible to short-term light/dark changes-induced degeneration

(2013) Mei Tian et al.   EXPERIMENTAL EYE RESEARCH

Bardet–Biedl syndrome proteins control the cilia length through regulation of actin polymerization

(2013) Victor Hernandez-Hernandez et al.   HUMAN MOLECULAR GENETICS

Usher protein functions in hair cells and photoreceptors

(2013) Dominic Cosgrove et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

TGF-β Signaling Is Associated with Endocytosis at the Pocket Region of the Primary Cilium

(2013) Christian Alexandro Clement et al.   Cell Reports

The Centrosome Regulates the Rab11- Dependent Recycling Endosome Pathway at Appendages of the Mother Centriole

(2012) Heidi Hehnly et al.   CURRENT BIOLOGY

The extracellular matrix and ciliary signaling

(2012) Tamina Seeger-Nukpezah et al.   CURRENT OPINION IN CELL BIOLOGY

Kinocilia Mediate Mechanosensitivity in Developing Zebrafish Hair Cells

(2012) Katie S. Kindt et al.   DEVELOPMENTAL CELL

The Lowe syndrome protein OCRL1 is involved in primary cilia assembly

(2012) Brian G. Coon et al.   HUMAN MOLECULAR GENETICS

OCRL localizes to the primary cilium: a new role for cilia in Lowe syndrome

(2012) Na Luo et al.   HUMAN MOLECULAR GENETICS

Regulated Vesicular Trafficking of Specific PCDH15 and VLGR1 Variants in Auditory Hair Cells

(2012) M. Zallocchi et al.   JOURNAL OF NEUROSCIENCE

Role for a Novel Usher Protein Complex in Hair Cell Synaptic Maturation

(2012) Marisa Zallocchi et al.   PLoS One

OCRL1 Modulates Cilia Length in Renal Epithelial Cells

(2012) Youssef Rbaibi et al.   TRAFFIC

The ciliary pocket: a once-forgotten membrane domain at the base of cilia

(2011) Rania Ghossoub et al.   BIOLOGY OF THE CELL

A Role for the Primary Cilium in Notch Signaling and Epidermal Differentiation during Skin Development

(2011) Ellen J. Ezratty et al.   CELL

Regulation of PCDH15 function in mechanosensory hair cells by alternative splicing of the cytoplasmic domain

(2011) S. W. Webb et al.   DEVELOPMENT

The ciliopathy gene cc2d2a controls zebrafish photoreceptor outer segment development through a role in Rab8-dependent vesicle trafficking

(2011) Ruxandra Bachmann-Gagescu et al.   HUMAN MOLECULAR GENETICS

Origin of Inner Ear Hair Cells: Morphological and Functional Differentiation from Ciliary Cells into Hair Cells in Zebrafish Inner Ear

(2011) M. Tanimoto et al.   JOURNAL OF NEUROSCIENCE

Primary cilia membrane assembly is initiated by Rab11 and transport protein particle II (TRAPPII) complex-dependent trafficking of Rabin8 to the centrosome

(2011) C. J. Westlake et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clustered protocadherin family

(2010) Takeshi Yagi   DEVELOPMENT GROWTH & DIFFERENTIATION

MIM and Cortactin Antagonism Regulates Ciliogenesis and Hedgehog Signaling

(2010) Marina Bershteyn et al.   DEVELOPMENTAL CELL

Alström Syndrome protein ALMS1 localizes to basal bodies of cochlear hair cells and regulates cilium-dependent planar cell polarity

(2010) Daniel Jagger et al.   HUMAN MOLECULAR GENETICS

Analysis of subcellular localization of Myo7a, Pcdh15 and Sans in Ush1c knockout mice

(2010) Denise Yan et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

The ciliary pocket: an endocytic membrane domain at the base of primary and motile cilia

(2010) A. Molla-Herman et al.   JOURNAL OF CELL SCIENCE

Development and Regeneration of Sensory Transduction in Auditory Hair Cells Requires Functional Interaction Between Cadherin-23 and Protocadherin-15

(2010) A. Lelli et al.   JOURNAL OF NEUROSCIENCE

Integrin α8β1 regulates adhesion, migration and proliferation of human intestinal crypt cells via a predominant RhoA/ROCK-dependent mechanism

(2009) Yannick D. Benoit et al.   BIOLOGY OF THE CELL

Primary cilia regulate hippocampal neurogenesis by mediating sonic hedgehog signaling

(2008) J. J. Breunig et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Centrins in retinal photoreceptor cells: Regulators in the connecting cilium

(2008) Philipp Trojan et al.   PROGRESS IN RETINAL AND EYE RESEARCH