Maternal DCAF2 is crucial for maintenance of genome stability during the first cell cycle in mice

A MAPK cascade couples maternal mRNA translation and degradation to meiotic cell cycle progression in mouse oocytes

(2016) Qian-Qian Sha et al.   DEVELOPMENT

Protein synthesis and degradation are essential to regulate germline stem cell homeostasis inDrosophilatestes

(2016) Jun Yu et al.   DEVELOPMENT

Geminin deletion in mouse oocytes results in impaired embryo development and reduced fertility

(2016) Xue-Shan Ma et al.   MOLECULAR BIOLOGY OF THE CELL

BTG4 is a meiotic cell cycle–coupled maternal-zygotic-transition licensing factor in oocytes

(2016) Chao Yu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

BTG4 is a meiotic cell cycle–coupled maternal-zygotic-transition licensing factor in oocytes

(2016) Chao Yu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Maternal BCAS2 protects genomic integrity in mouse early embryonic development

(2015) Qianhua Xu et al.   DEVELOPMENT

Stella preserves maternal chromosome integrity by inhibiting 5hmC-induced  H2AX accumulation

(2015) T. Nakatani et al.   EMBO REPORTS

Sequential replication-coupled destruction at G1/S ensures genome stability

(2015) Kate E. Coleman et al.   GENES & DEVELOPMENT

Development and characterization of a novel long-acting recombinant follicle stimulating hormone agonist by fusing Fc to an FSH-β subunit

(2015) Yin-Li Zhang et al.   HUMAN REPRODUCTION

Cellular and molecular regulation of the activation of mammalian primordial follicles: somatic cells initiate follicle activation in adulthood

(2015) Hua Zhang et al.   HUMAN REPRODUCTION UPDATE

ERK1/2 Activities Are Dispensable for Oocyte Growth but Are Required for Meiotic Maturation and Pronuclear Formation in Mouse

(2015) Yin-Li Zhang et al.   Journal of Genetics and Genomics

CRL4–DCAF1 ubiquitin E3 ligase directs protein phosphatase 2A degradation to control oocyte meiotic maturation

(2015) Chao Yu et al.   Nature Communications

Cdt2-mediated XPG degradation promotes gap-filling DNA synthesis in nucleotide excision repair

(2014) Chunhua Han et al.   CELL CYCLE

Maturation-associatedDbf4expression is essential for mouse zygotic DNA replication

(2014) Shin Murai et al.   DEVELOPMENT GROWTH & DIFFERENTIATION

CRL4DCAF1 is required in activated oocytes for follicle maintenance and ovulation

(2014) C. Yu et al.   MOLECULAR HUMAN REPRODUCTION

The DNA damage checkpoint pathway promotes extensive resection and nucleotide synthesis to facilitate homologous recombination repair and genome stability in fission yeast

(2014) Elizabeth J. Blaikley et al.   NUCLEIC ACIDS RESEARCH

Laser microbeam-induced DNA damage inhibits cell division in fertilized eggs and early embryos

(2013) Zhong-Wei Wang et al.   CELL CYCLE

Ubiquitin E3 Ligase CRL4CDT2/DCAF2as a Potential Chemotherapeutic Target for Ovarian Surface Epithelial Cancer

(2013) Wei-Wei Pan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CRL4 Complex Regulates Mammalian Oocyte Survival and Reprogramming by Activation of TET Proteins

(2013) C. Yu et al.   SCIENCE

PGC7 binds histone H3K9me2 to protect against conversion of 5mC to 5hmC in early embryos

(2012) Toshinobu Nakamura et al.   NATURE

CRL4Cdt2

(2011) Tarek Abbas et al.   CELL CYCLE

Cul4A is essential for spermatogenesis and male fertility

(2011) Dragana Kopanja et al.   DEVELOPMENTAL BIOLOGY

Mechanism of CRL4Cdt2, a PCNA-dependent E3 ubiquitin ligase

(2011) C. G. Havens et al.   GENES & DEVELOPMENT

N-Methyl-N′-nitro-N-nitrosoguanidine (MNNG) Triggers MSH2 and Cdt2 Protein-dependent Degradation of the Cell Cycle and Mismatch Repair (MMR) Inhibitor Protein p21Waf1/Cip1

(2011) Thomas Jascur et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Selective Ubiquitylation of p21 and Cdt1 by UBCH8 and UBE2G Ubiquitin-Conjugating Enzymes via the CRL4Cdt2 Ubiquitin Ligase Complex

(2011) E. Shibata et al.   MOLECULAR AND CELLULAR BIOLOGY

The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes

(2011) Tian-Peng Gu et al.   NATURE

De novo DNA methylation: a germ cell perspective

(2011) Sébastien A. Smallwood et al.   TRENDS IN GENETICS

Dynamic Replacement of Histone H3 Variants Reprograms Epigenetic Marks in Early Mouse Embryos

(2011) Tomohiko Akiyama et al.   PLoS Genetics

Dynamics of Cullin-RING Ubiquitin Ligase Network Revealed by Systematic Quantitative Proteomics

(2010) Eric J. Bennett et al.   CELL

Genome-Wide Reprogramming in the Mouse Germ Line Entails the Base Excision Repair Pathway

(2010) P. Hajkova et al.   SCIENCE

Genomic imbalances in rhabdomyosarcoma cell lines affect expression of genes frequently altered in primary tumors: An approach to identify candidate genes involved in tumor development

(2009) Edoardo Missiaglia et al.   GENES CHROMOSOMES & CANCER

The CRL4Cdt2 ubiquitin ligase targets the degradation of p21Cip1 to control replication licensing

(2008) Y. Kim et al.   GENES & DEVELOPMENT

Involvement of elevated expression of multiple cell-cycle regulator, DTL/RAMP (denticleless/RA-regulated nuclear matrix associated protein), in the growth of breast cancer cells

(2008) T Ueki et al.   ONCOGENE