Disruption of Rab8a and Rab11a causes formation of basolateral microvilli in neonatal enteropathy

The role of enterocyte defects in the pathogenesis of congenital diarrheal disorders

(2016) Arend W. Overeem et al.   Disease Models & Mechanisms

Three mechanisms control E-cadherin localization to the zonula adherens

(2016) Innokenty Woichansky et al.   Nature Communications

Coordinating Neuronal Actin–Microtubule Dynamics

(2015) Charlotte H. Coles et al.   CURRENT BIOLOGY

Rab8a vesicles regulate Wnt ligand delivery and Paneth cell maturation at the intestinal stem cell niche

(2015) S. Das et al.   DEVELOPMENT

Microtubule-dependent apical restriction of recycling endosomes sustains adherens junctions during morphogenesis of the Drosophila tracheal system

(2015) P.-M. Le Droguen et al.   DEVELOPMENT

Formin-like 2 Promotes β1-Integrin Trafficking and Invasive Motility Downstream of PKCα

(2015) Ying Wang et al.   DEVELOPMENTAL CELL

Cargo-selective apical exocytosis in epithelial cells is conducted by Myo5B, Slp4a, Vamp7, and Syntaxin 3

(2015) Georg F. Vogel et al.   JOURNAL OF CELL BIOLOGY

Rab11a regulates syntaxin 3 localization and microvillus assembly in enterocytes

(2015) B. C. Knowles et al.   JOURNAL OF CELL SCIENCE

Cordon bleu promotes the assembly of brush border microvilli

(2015) Nathan E. Grega-Larson et al.   MOLECULAR BIOLOGY OF THE CELL

An inducible mouse model for microvillus inclusion disease reveals a role for myosin Vb in apical and basolateral trafficking

(2015) Kerstin Schneeberger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanisms of apical–basal axis orientation and epithelial lumen positioning

(2015) Arend W. Overeem et al.   TRENDS IN CELL BIOLOGY

Myo5b knockout mice as a model of microvillus inclusion disease

(2015) Fernando Cartón-García et al.   Scientific Reports

TLR sorting by Rab11 endosomes maintains intestinal epithelial‐microbial homeostasis

(2014) Shiyan Yu et al.   EMBO JOURNAL

Apical Vesicle Trafficking Takes Center Stage in Neonatal Enteropathies

(2014) Byron C. Knowles et al.   GASTROENTEROLOGY

Loss of Syntaxin 3 Causes Variant Microvillus Inclusion Disease

(2014) Caroline L. Wiegerinck et al.   GASTROENTEROLOGY

Global Ablation of the Mouse Rab11a Gene Impairs Early Embryogenesis and Matrix Metalloproteinase Secretion

(2014) Shiyan Yu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Shaping the intestinal brush border

(2014) Scott W. Crawley et al.   JOURNAL OF CELL BIOLOGY

Myosin Vb and Rab11a regulate phosphorylation of ezrin in enterocytes

(2014) H. S. Dhekne et al.   JOURNAL OF CELL SCIENCE

Myosin Vb uncoupling from RAB8A and RAB11A elicits microvillus inclusion disease

(2014) Byron C. Knowles et al.   JOURNAL OF CLINICAL INVESTIGATION

Organization and execution of the epithelial polarity programme

(2014) Enrique Rodriguez-Boulan et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Actin–microtubule coordination at growing microtubule ends

(2014) Magdalena Preciado López et al.   Nature Communications

Rab11a is required for apical protein localisation in the intestine

(2014) T. Sobajima et al.   Biology Open

Cdc42 Coordinates Proliferation, Polarity, Migration, and Differentiation of Small Intestinal Epithelial Cells in Mice

(2013) Jaime Melendez et al.   GASTROENTEROLOGY

An Overview and Online Registry of Microvillus Inclusion Disease Patients and theirMYO5BMutations

(2013) K. Joeri van der Velde et al.   HUMAN MUTATION

Rab8a and Rab8b are essential for several apical transport pathways but insufficient for ciliogenesis

(2013) T. Sato et al.   JOURNAL OF CELL SCIENCE

Rab25 regulates integrin expression in polarized colonic epithelial cells

(2013) Moorthy Krishnan et al.   MOLECULAR BIOLOGY OF THE CELL

Microvillus Inclusion Disease: Loss of Myosin Vb Disrupts Intracellular Traffic and Cell Polarity

(2013) Cornelia E. Thoeni et al.   TRAFFIC

Myosin-V Is Activated by Binding Secretory Cargo and Released in Coordination with Rab/Exocyst Function

(2012) Kirk W. Donovan et al.   DEVELOPMENTAL CELL

Cdc42 and Rab8a are critical for intestinal stem cell division, survival, and differentiation in mice

(2012) Ryotaro Sakamori et al.   JOURNAL OF CLINICAL INVESTIGATION

Synaptotagmin-like proteins control the formation of a single apical membrane domain in epithelial cells

(2012) Manuel Gálvez-Santisteban et al.   NATURE CELL BIOLOGY

Role of membrane traffic in the generation of epithelial cell asymmetry

(2012) Gerard Apodaca et al.   NATURE CELL BIOLOGY

Integrins and cadherins join forces to form adhesive networks

(2011) G. F. Weber et al.   JOURNAL OF CELL SCIENCE

Functional Characterization of Mutations in the Myosin Vb Gene Associated With Microvillus Inclusion Disease

(2011) Agata M Szperl et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Ezrin-mediated apical integrity is required for intestinal homeostasis

(2011) J. B. Casaletto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rab GTPase-Myo5B complexes control membrane recycling and epithelial polarization

(2011) J. T. Roland et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A possible mechanism for ezrin to establish epithelial cell polarity

(2010) Lixin Zhu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

aPKC Phosphorylation of Bazooka Defines the Apical/Lateral Border in Drosophila Epithelial Cells

(2010) Eurico Morais-de-Sá et al.   CELL

Myosin motor function: the ins and outs of actin-based membrane protrusions

(2010) Rajalakshmi Nambiar et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Crumbs/DaPKC-Dependent Apical Exclusion of Bazooka Promotes Photoreceptor Polarity Remodeling

(2010) Rhian F. Walther et al.   CURRENT BIOLOGY

Cdx2 regulates endo-lysosomal function and epithelial cell polarity

(2010) N. Gao et al.   GENES & DEVELOPMENT

Loss-of-function of MYO5B is the main cause of microvillus inclusion disease: 15 novel mutations and a CaCo-2 RNAi cell model

(2010) Frank M. Ruemmele et al.   HUMAN MUTATION

Formation of a Bazooka–Stardust complex is essential for plasma membrane polarity in epithelia

(2010) Michael P. Krahn et al.   JOURNAL OF CELL BIOLOGY

Loss of Rab25 promotes the development of intestinal neoplasia in mice and is associated with human colorectal adenocarcinomas

(2010) Ki Taek Nam et al.   JOURNAL OF CLINICAL INVESTIGATION

Mst4 and Ezrin Induce Brush Borders Downstream of the Lkb1/Strad/Mo25 Polarization Complex

(2009) Jean Paul ten Klooster et al.   DEVELOPMENTAL CELL

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

(2009) Toshiro Sato et al.   NATURE

Rab11 Helps Maintain Apical Crumbs and Adherens Junctions in the Drosophila Embryonic Ectoderm

(2009) Jeremiah F. Roeth et al.   PLoS One

Active Rab11 and functional recycling endosome are required for E-cadherin trafficking and lumen formation during epithelial morphogenesis

(2008) Marion Desclozeaux et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Alternative Splicing in Class V Myosins Determines Association with Rab10

(2008) Joseph T. Roland et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rab-coupling protein coordinates recycling of α5β1 integrin and EGFR1 to promote cell migration in 3D microenvironments

(2008) Patrick T. Caswell et al.   JOURNAL OF CELL BIOLOGY

Rab8 Regulates Basolateral Secretory, But Not Recycling, Traffic at the Recycling Endosome

(2008) Lauren Henry et al.   MOLECULAR BIOLOGY OF THE CELL

MYO5B mutations cause microvillus inclusion disease and disrupt epithelial cell polarity

(2008) Thomas Müller et al.   NATURE GENETICS

From cells to organs: building polarized tissue

(2008) David M. Bryant et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY