Neuropilin 1 binds PDGF-D and is a co-receptor in PDGF-D–PDGFRβ signaling

The expanding role of neuropilin

(2016) Natalie Kofler et al.   CURRENT OPINION IN HEMATOLOGY

Functional malignant cell heterogeneity in pancreatic neuroendocrine tumors revealed by targeting of PDGF-DD

(2016) Eliane Cortez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuropilin-1 mediates vascular permeability independently of vascular endothelial growth factor receptor-2 activation

(2016) Lise Roth et al.   Science Signaling

Neuropilin-1 mediates vascular permeability independently of vascular endothelial growth factor receptor-2 activation

(2016) Lise Roth et al.   Science Signaling

Mice Lacking Platelet-Derived Growth Factor D Display a Mild Vascular Phenotype

(2016) Hanna Gladh et al.   PLoS One

Neuropilins 1 and 2 mediate neointimal hyperplasia and re-endothelialization following arterial injury

(2015) Caroline Pellet-Many et al.   CARDIOVASCULAR RESEARCH

PDGF-D signaling in portal myofibroblasts and hepatic stellate cells proves identical to PDGF-B via both PDGF receptor type α and β

(2015) Erawan Borkham-Kamphorst et al.   CELLULAR SIGNALLING

Dynamic Regulation of Platelet-derived Growth Factor D (PDGF-D) Activity and Extracellular Spatial Distribution by Matriptase-mediated Proteolysis

(2015) Wei Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Alk1 and Alk5 inhibition by Nrp1 controls vascular sprouting downstream of Notch

(2015) Irene Maria Aspalter et al.   Nature Communications

Neuropilin 1 (NRP1) hypomorphism combined with defective VEGF-A binding reveals novel roles for NRP1 in developmental and pathological angiogenesis

(2014) A. Fantin et al.   DEVELOPMENT

NRP1 Presented in trans to the Endothelium Arrests VEGFR2 Endocytosis, Preventing Angiogenic Signaling and Tumor Initiation

(2014) Sina Koch et al.   DEVELOPMENTAL CELL

Neuropilin Regulation of Angiogenesis, Arteriogenesis, and Vascular Permeability

(2014) Alice Plein et al.   MICROCIRCULATION

Pericyte-endothelial crosstalk: implications and opportunities for advanced cellular therapies

(2014) Anita Geevarghese et al.   Translational Research

Neuropilin-1 functions as a VEGFR2 co-receptor to guide developmental angiogenesis independent of ligand binding

(2014) Maria V Gelfand et al.   eLife

Analysis of Mice Lacking the Heparin-Binding Splice Isoform of Platelet-Derived Growth Factor A

(2013) J. Andrae et al.   MOLECULAR AND CELLULAR BIOLOGY

New prospects in the roles of the C-terminal domains of VEGF-A and their cooperation for ligand binding, cellular signaling and vessels formation

(2012) Romain Delcombel et al.   ANGIOGENESIS

Neuropilin signalling in angiogenesis

(2012) Sina Koch   BIOCHEMICAL SOCIETY TRANSACTIONS

Genome-wide studies of gene expression relevant to coronary artery disease

(2012) Jeffrey Hsu et al.   CURRENT OPINION IN CARDIOLOGY

Structural Basis for Selective Vascular Endothelial Growth Factor-A (VEGF-A) Binding to Neuropilin-1

(2012) Matthew W. Parker et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neuropilin-1 mediates PDGF stimulation of vascular smooth muscle cell migration and signalling via p130Cas

(2011) Caroline Pellet-Many et al.   BIOCHEMICAL JOURNAL

Neuropilin-1 promotes VEGFR-2 trafficking through Rab11 vesicles thereby specifying signal output

(2011) K. Ballmer-Hofer et al.   BLOOD

Pericytes: Developmental, Physiological, and Pathological Perspectives, Problems, and Promises

(2011) Annika Armulik et al.   DEVELOPMENTAL CELL

Neuropilin-1 regulates platelet-derived growth factor receptor signalling in mesenchymal stem cells

(2010) Stephen G. Ball et al.   BIOCHEMICAL JOURNAL

Emerging roles of PDGF-D signaling pathway in tumor development and progression

(2010) Zhiwei Wang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

A Novel Signaling Axis of Matriptase/PDGF-D/ -PDGFR in Human Prostate Cancer

(2010) C. V. Ustach et al.   CANCER RESEARCH

VEGF Receptor 2 Endocytic Trafficking Regulates Arterial Morphogenesis

(2010) Anthony A. Lanahan et al.   DEVELOPMENTAL CELL

Neuropilin-1 promotes cirrhosis of the rodent and human liver by enhancing PDGF/TGF-β signaling in hepatic stellate cells

(2010) Sheng Cao et al.   JOURNAL OF CLINICAL INVESTIGATION

Structures of a platelet-derived growth factor/propeptide complex and a platelet-derived growth factor/receptor complex

(2010) A. Hye-Ryong Shim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation of Protein Kinase C α Is Necessary for Sorting the PDGF β-Receptor to Rab4a-dependent Recycling

(2009) Carina Hellberg et al.   MOLECULAR BIOLOGY OF THE CELL

Neuropilins: structure, function and role in disease

(2008) Caroline Pellet-Many et al.   BIOCHEMICAL JOURNAL

Orf virus VEGF-E NZ2 promotes paracellular NRP-1/VEGFR-2 coreceptor assembly via the peptide RPPR

(2008) Stéphanie Cébe-Suarez et al.   FASEB JOURNAL

Role of platelet-derived growth factors in physiology and medicine

(2008) J. Andrae et al.   GENES & DEVELOPMENT

The uPA/uPAR system regulates the bioavailability of PDGF-DD: implications for tumour growth

(2008) M Ehnman et al.   ONCOGENE