Defective signaling, osteoblastogenesis and bone remodeling in a mouse model of connexin 43 C-terminal truncation

Removing or truncating connexin 43 in murine osteocytes alters cortical geometry, nanoscale morphology, and tissue mechanics in the tibia

(2016) Max A. Hammond et al.   BONE

Communication of cAMP by connexin43 gap junctions regulates osteoblast signaling and gene expression

(2016) Aditi Gupta et al.   CELLULAR SIGNALLING

Connexins in the skeleton

(2016) Joseph P. Stains et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

HIF-1α regulates bone formation after osteogenic mechanical loading

(2015) Ryan E. Tomlinson et al.   BONE

Connexin 43 Channels Are Essential for Normal Bone Structure and Osteocyte Viability

(2015) Huiyun Xu et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Evidence for the role of connexin 43-mediated intercellular communication in the process of intracortical bone resorption via osteocytic osteolysis

(2014) Shane A Lloyd et al.   BMC MUSCULOSKELETAL DISORDERS

Connexin43 enhances the expression of osteoarthritis-associated genes in synovial fibroblasts in culture

(2014) Aditi Gupta et al.   BMC MUSCULOSKELETAL DISORDERS

Mechanisms linking connexin mutations to human diseases

(2014) John J. Kelly et al.   CELL AND TISSUE RESEARCH

Syndromic and non-syndromic disease-linked Cx43 mutations

(2014) Dale W. Laird   FEBS LETTERS

Gap junctional regulation of signal transduction in bone cells

(2014) Atum M. Buo et al.   FEBS LETTERS

Characterization of Fibrillar Collagens and Extracellular Matrix of Glandular Benign Prostatic Hyperplasia Nodules

(2014) Tyler M. Bauman et al.   PLoS One

Connexin 43 hemichannels and intracellular signaling in bone cells

(2014) Lilian I. Plotkin   Frontiers in Physiology

Connexin 43 deficiency desensitizes bone to the effects of mechanical unloading through modulation of both arms of bone remodeling

(2013) Shane A. Lloyd et al.   BONE

The regulation of runt-related transcription factor 2 by fibroblast growth factor-2 and connexin43 requires the inositol polyphosphate/protein kinase Cδ cascade

(2013) Corinne Niger et al.   JOURNAL OF BONE AND MINERAL RESEARCH

An intact connexin43 is required to enhance signaling and gene expression in osteoblast-like cells

(2013) Carla Hebert et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Absence of Cx43 selectively from osteocytes enhances responsiveness to mechanical force in mice

(2013) Nicoletta Bivi et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

The role of estrogen and androgen receptors in bone health and disease

(2013) Stavros C. Manolagas et al.   Nature Reviews Endocrinology

ERK acts in parallel to PKCδ to mediate the connexin43-dependent potentiation of Runx2 activity by FGF2 in MC3T3 osteoblasts

(2012) Corinne Niger et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Bisphosphonates improve trabecular bone mass and normalize cortical thickness in ovariectomized, osteoblast connexin43 deficient mice

(2012) Marcus P. Watkins et al.   BONE

Beyond gap junctions: Connexin43 and bone cell signaling

(2012) Lilian I. Plotkin et al.   BONE

Deletion of Cx43 from Osteocytes Results in Defective Bone Material Properties but Does Not Decrease Extrinsic Strength in Cortical Bone

(2012) Nicoletta Bivi et al.   CALCIFIED TISSUE INTERNATIONAL

Gap-junction-mediated cell-to-cell communication

(2012) Jean-Claude Hervé et al.   CELL AND TISSUE RESEARCH

Celastrus and Its Bioactive Celastrol Protect against Bone Damage in Autoimmune Arthritis by Modulating Osteoimmune Cross-talk

(2012) Siddaraju M. Nanjundaiah et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Standardized nomenclature, symbols, and units for bone histomorphometry: A 2012 update of the report of the ASBMR Histomorphometry Nomenclature Committee

(2012) David W Dempster et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Mechanical stress-activated integrin  5 1 induces opening of connexin 43 hemichannels

(2012) N. Batra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The connexin43 carboxyl terminus and cardiac gap junction organization

(2011) Joseph A. Palatinus et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Gap junctional channels are parts of multiprotein complexes

(2011) Jean-Claude Hervé et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

The transcriptional activity of osterix requires the recruitment of Sp1 to the osteocalcin proximal promoter

(2011) Corinne Niger et al.   BONE

Cell autonomous requirement of connexin 43 for osteocyte survival: Consequences for endocortical resorption and periosteal bone formation

(2011) Nicoletta Bivi et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Connexin43 interacts with βarrestin: A pre-requisite for osteoblast survival induced by parathyroid hormone

(2011) Nicoletta Bivi et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Osteoblast connexin43 modulates skeletal architecture by regulating both arms of bone remodeling

(2011) Marcus Watkins et al.   MOLECULAR BIOLOGY OF THE CELL

Enhanced Osteoclastic Resorption and Responsiveness to Mechanical Load in Gap Junction Deficient Bone

(2011) Yue Zhang et al.   PLoS One

Homozygosity for a Missense Mutation in SERPINH1, which Encodes the Collagen Chaperone Protein HSP47, Results in Severe Recessive Osteogenesis Imperfecta

(2010) Helena E. Christiansen et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Interaction of connexin43 and protein kinase C-delta during FGF2 signaling

(2010) Corinne Niger et al.   BMC BIOCHEMISTRY

Pivotal role of Twist in skeletal biology and pathology

(2010) Hichem Miraoui et al.   GENE

Guidelines for assessment of bone microstructure in rodents using micro-computed tomography

(2010) Mary L Bouxsein et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Skeletal sexual dimorphism: relative contribution of sex steroids, GH–IGF1, and mechanical loading

(2010) Filip Callewaert et al.   JOURNAL OF ENDOCRINOLOGY

Connexin43 phosphorylation: structural changes and biological effects

(2009) Joell L. Solan et al.   BIOCHEMICAL JOURNAL

Cx43 CT domain influences infarct size and susceptibility to ventricular tachyarrhythmias in acute myocardial infarction

(2009) Karen Maass et al.   CARDIOVASCULAR RESEARCH

Sexual dimorphism in cortical bone size and strength but not density is determined by independent and time-specific actions of sex steroids and IGF-1: Evidence from pubertal mouse models

(2009) Filip Callewaert et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Involvement of the Cytoplasmic C-Terminal Domain of Connexin43 in Neuronal Migration

(2009) C. Cina et al.   JOURNAL OF NEUROSCIENCE

Connexin43 Potentiates Osteoblast Responsiveness to Fibroblast Growth Factor 2 via a Protein Kinase C-Delta/Runx2–dependent Mechanism

(2009) Florence Lima et al.   MOLECULAR BIOLOGY OF THE CELL

A Missense Mutation in the SERPINH1 Gene in Dachshunds with Osteogenesis Imperfecta

(2009) Cord Drögemüller et al.   PLoS Genetics