BAIAP3, a C2 domain–containing Munc13 protein, controls the fate of dense-core vesicles in neuroendocrine cells

Munc13-4 functions as a Ca2+ sensor for homotypic secretory granule fusion to generate endosomal exocytic vacuoles

(2017) Sang Su Woo et al.   MOLECULAR BIOLOGY OF THE CELL

The Vesicle Priming Factor CAPS Functions as a Homodimer via C2 Domain Interactions to Promote Regulated Vesicle Exocytosis

(2016) Matt Petrie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

How the stimulus defines the dynamics of vesicle pool recruitment, fusion mode, and vesicle recycling in neuroendocrine cells

(2016) Ana María Cárdenas et al.   JOURNAL OF NEUROCHEMISTRY

C2-domain containing calcium sensors in neuroendocrine secretion

(2016) Paulo S. Pinheiro et al.   JOURNAL OF NEUROCHEMISTRY

Munc13-4 interacts with syntaxin 7 and regulates late endosomal maturation, endosomal signaling, and TLR9-initiated cellular responses

(2016) Jing He et al.   MOLECULAR BIOLOGY OF THE CELL

Extended synaptotagmins are Ca2+-dependent lipid transfer proteins at membrane contact sites

(2016) Haijia Yu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ferlins Show Tissue-Specific Expression and Segregate as Plasma Membrane/Late Endosomal or Trans-Golgi/Recycling Ferlins

(2016) Gregory M. I. Redpath et al.   TRAFFIC

The calcium sensor Copine-6 regulates spine structural plasticity and learning and memory

(2016) Judith R. Reinhard et al.   Nature Communications

The Synaptic Vesicle Release Machinery

(2015) Josep Rizo et al.   Annual Review of Biophysics

Munc13-4 Is a Rab11-binding Protein That Regulates Rab11-positive Vesicle Trafficking and Docking at the Plasma Membrane

(2015) Jennifer L. Johnson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Multiple C2domains transmembrane protein 1 is expressed in CNS neurons and possibly regulates cellular vesicle retrieval and oxidative stress

(2015) Lifeng Qiu et al.   JOURNAL OF NEUROCHEMISTRY

A Fluorescent Live Imaging Screening Assay Based on Translocation Criteria Identifies Novel Cytoplasmic Proteins Implicated in G Protein-coupled Receptor Signaling Pathways

(2015) Sandra Lecat et al.   MOLECULAR & CELLULAR PROTEOMICS

Extreme obesity is associated with variation in genes related to the circadian rhythm of food intake and hypothalamic signaling

(2015) Edwin C. M. Mariman et al.   PHYSIOLOGICAL GENOMICS

Insulin secretory granules control autophagy in pancreatic   cells

(2015) A. Goginashvili et al.   SCIENCE

Identification of a Munc13-sensitive step in chromaffin cell large dense-core vesicle exocytosis

(2015) Kwun Nok M Man et al.   eLife

The Molecular Machinery of Neurotransmitter Release (Nobel Lecture)

(2014) Thomas C. Südhof   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Signaling through C2 domains: More than one lipid target

(2014) Senena Corbalan-Garcia et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

DOC2 isoforms play dual roles in insulin secretion and insulin-stimulated glucose uptake

(2014) Jia Li et al.   DIABETOLOGIA

The SNARE protein vti1a functions in dense-core vesicle biogenesis

(2014) A. M. Walter et al.   EMBO JOURNAL

Two Rab2 Interactors Regulate Dense-Core Vesicle Maturation

(2014) Michael Ailion et al.   NEURON

VAMP4 is required to maintain the ribbon structure of the Golgi apparatus

(2013) Akiko Shitara et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Unknown

(2013) Sonja Wojcik et al.   MOLECULAR MEDICINE

Neuropeptides in epilepsy

(2013) Stjepana Kovac et al.   NEUROPEPTIDES

Rab27 Effectors, Pleiotropic Regulators in Secretory Pathways

(2013) Mitsunori Fukuda   TRAFFIC

Tethering the assembly of SNARE complexes

(2013) WanJin Hong et al.   TRENDS IN CELL BIOLOGY

Widespread Dysregulation of Peptide Hormone Release in Mice Lacking Adaptor Protein AP-3

(2013) Daniel W. Sirkis et al.   PLoS Genetics

Exocytosis and Endocytosis in Neuroendocrine Cells: Inseparable Membranes!

(2013) Sébastien Houy et al.   Frontiers in Endocrinology

CAPS and Munc13: CATCHRs that SNARE Vesicles

(2013) Declan J. James et al.   Frontiers in Endocrinology

Regulation of the Golgi complex by phospholipid remodeling enzymes

(2012) Kevin D. Ha et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Munc13-4 reconstitutes calcium-dependent SNARE-mediated membrane fusion

(2012) Kristin L. Boswell et al.   JOURNAL OF CELL BIOLOGY

Molecular machines governing exocytosis of synaptic vesicles

(2012) Reinhard Jahn et al.   NATURE

The Presynaptic Active Zone

(2012) Thomas C. Südhof   NEURON

TBC-8, a Putative RAB-2 GAP, Regulates Dense Core Vesicle Maturation in Caenorhabditis elegans

(2012) Mandy Hannemann et al.   PLoS Genetics

Activity-Dependent IGF-1 Exocytosis Is Controlled by the Ca2+-Sensor Synaptotagmin-10

(2011) Peng Cao et al.   CELL

Doc2 Is a Ca2+ Sensor Required for Asynchronous Neurotransmitter Release

(2011) Jun Yao et al.   CELL

The COG complex interacts directly with Syntaxin 6 and positively regulates endosome-to-TGN retrograde transport

(2011) Orly Laufman et al.   JOURNAL OF CELL BIOLOGY

Calpain-6, a microtubule-stabilizing protein, regulates Rac1 activity and cell motility through interaction with GEF-H1

(2011) K. Tonami et al.   JOURNAL OF CELL SCIENCE

Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment

(2011) Jürgen Cox et al.   JOURNAL OF PROTEOME RESEARCH

Tollip: a multitasking protein in innate immunity and protein trafficking

(2011) Daniel G.S. Capelluto   MICROBES AND INFECTION

RIM Proteins Activate Vesicle Priming by Reversing Autoinhibitory Homodimerization of Munc13

(2011) Lunbin Deng et al.   NEURON

Regulation of the Bcas1 and Baiap3 transcripts in the subthalamic nucleus in mice recovering from MPTP toxicity

(2011) J.B. Lauridsen et al.   NEUROSCIENCE RESEARCH

RNAi screen identifies a role for adaptor protein AP-3 in sorting to the regulated secretory pathway

(2010) Cédric S. Asensio et al.   JOURNAL OF CELL BIOLOGY

Secretory Granule Membrane Protein Recycles through Multivesicular Bodies

(2010) Nils Bäck et al.   TRAFFIC

Impaired dense core vesicle maturation inCaenorhabditis elegansmutants lacking Rab2

(2009) Stacey L. Edwards et al.   JOURNAL OF CELL BIOLOGY

Remote Homology between Munc13 MUN Domain and Vesicle Tethering Complexes

(2009) Jimin Pei et al.   JOURNAL OF MOLECULAR BIOLOGY

Statistical methods for analysis of high-throughput RNA interference screens

(2009) Amanda Birmingham et al.   NATURE METHODS

Membrane Fusion: Grappling with SNARE and SM Proteins

(2009) T. C. Sudhof et al.   SCIENCE

Binding of the Munc13-1 MUN Domain to Membrane-Anchored SNARE Complexes†

(2008) Rong Guan et al.   BIOCHEMISTRY

A 20-nm Step toward the Cell Membrane Preceding Exocytosis May Correspond to Docking of Tethered Granules

(2008) Erdem Karatekin et al.   BIOPHYSICAL JOURNAL

Tracing the Retrograde Route in Protein Trafficking

(2008) Ludger Johannes et al.   CELL

A syntaxin 10–SNARE complex distinguishes two distinct transport routes from endosomes to the trans-Golgi in human cells

(2008) Ian G. Ganley et al.   JOURNAL OF CELL BIOLOGY

Requirement of the Human GARP Complex for Mannose 6-phosphate-receptor-dependent Sorting of Cathepsin D to Lysosomes

(2008) F. Javier Pérez-Victoria et al.   MOLECULAR BIOLOGY OF THE CELL

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY