The innate immune response in human tuberculosis

The C-Type Lectin Receptor CLECSF8/CLEC4D Is a Key Component of Anti-Mycobacterial Immunity

(2015) Gillian J. Wilson et al.   Cell Host & Microbe

Inhibition of Autophagy by MiR-30A Induced by Mycobacteria tuberculosis as a Possible Mechanism of Immune Escape in Human Macrophages

(2015) Zhi Chen et al.   JAPANESE JOURNAL OF INFECTIOUS DISEASES

IFNG-mediated immune responses enhance autophagy againstMycobacterium tuberculosisantigens in patients with active tuberculosis

(2014) Ana I Rovetta et al.   Autophagy

Human Lung Epithelial Cells Contain Mycobacterium tuberculosis in a Late Endosomal Vacuole and Are Efficiently Recognized by CD8+ T Cells

(2014) Melanie J. Harriff et al.   PLoS One

An outer membrane channel protein of Mycobacterium tuberculosis with exotoxin activity

(2014) O. Danilchanka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Early clearance ofMycobacterium tuberculosis: a new frontier in prevention

(2013) Ayesha J. Verrall et al.   IMMUNOLOGY

Mycobacterium tuberculosis Exploits Human Interferon γ to Stimulate Macrophage Extracellular Trap Formation and Necrosis

(2013) Ka-Wing Wong et al.   JOURNAL OF INFECTIOUS DISEASES

Mycobacterium tuberculosis-Induced Neutrophil Extracellular Traps Activate Human Macrophages

(2013) Clara Braian et al.   Journal of Innate Immunity

ESX-1 dependent impairment of autophagic flux byMycobacterium tuberculosisin human dendritic cells

(2012) Alessandra Romagnoli et al.   Autophagy

ESX-1-mediated translocation to the cytosol controls virulence of mycobacteria

(2012) Diane Houben et al.   CELLULAR MICROBIOLOGY

Escape of Mycobacterium tuberculosis from oxidative killing by neutrophils

(2012) Björn Corleis et al.   CELLULAR MICROBIOLOGY

The Role of Airway Epithelial Cells in Response to Mycobacteria Infection

(2012) Yong Li et al.   Clinical & Developmental Immunology

NOD2 enhances the innate response of alveolar macrophages to Mycobacterium tuberculosis in humans

(2012) Esmeralda Juárez et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Phagosomal Rupture by Mycobacterium tuberculosis Results in Toxicity and Host Cell Death

(2012) Roxane Simeone et al.   PLoS Pathogens

Escape from the Phagosome: The Explanation for MHC-I Processing of Mycobacterial Antigens?

(2012) Melanie J. Harriff et al.   Frontiers in Immunology

Mycobacterial P1-Type ATPases Mediate Resistance to Zinc Poisoning in Human Macrophages

(2011) Hélène Botella et al.   Cell Host & Microbe

Critical role for NLRP3 in necrotic death triggered by Mycobacterium tuberculosis

(2011) Ka-Wing Wong et al.   CELLULAR MICROBIOLOGY

Autophagy modulates the Mycobacterium tuberculosis-induced cytokine response

(2011) Johanneke Kleinnijenhuis et al.   IMMUNOLOGY

In vitro differentiation of human macrophages with enhanced antimycobacterial activity

(2011) Guillaume Vogt et al.   JOURNAL OF CLINICAL INVESTIGATION

Human Lung Hydrolases Delineate Mycobacterium tuberculosis-Macrophage Interactions and the Capacity To Control Infection

(2011) J. Arcos et al.   JOURNAL OF IMMUNOLOGY

Germline CYBB mutations that selectively affect macrophages in kindreds with X-linked predisposition to tuberculous mycobacterial disease

(2011) Jacinta Bustamante et al.   NATURE IMMUNOLOGY

Polymorphic Allele of Human IRGM1 Is Associated with Susceptibility to Tuberculosis in African Americans

(2011) Katherine Y. King et al.   PLoS One

Human Macrophages Infected with a High Burden of ESAT-6-Expressing M. tuberculosis Undergo Caspase-1- and Cathepsin B-Independent Necrosis

(2011) Amanda Welin et al.   PLoS One

Mycobacterium tuberculosis protein tyrosine phosphatase (PtpA) excludes host vacuolar-H+-ATPase to inhibit phagosome acidification

(2011) D. Wong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mycobacterium tuberculosis components stimulate production of the antimicrobial peptide hepcidin

(2011) Fatoumata B. Sow et al.   TUBERCULOSIS

Identification of a novel IRGM promoter single nucleotide polymorphism associated with tuberculosis

(2010) Nanying Che et al.   CLINICA CHIMICA ACTA

Intracellular generation of superoxide by the phagocyte NADPH oxidase: How, where, and what for?

(2010) Johan Bylund et al.   FREE RADICAL BIOLOGY AND MEDICINE

Human Mucosal Associated Invariant T Cells Detect Bacterially Infected Cells

(2010) Marielle C. Gold et al.   PLOS BIOLOGY

The Type I NADH Dehydrogenase of Mycobacterium tuberculosis Counters Phagosomal NOX2 Activity to Inhibit TNF-α-Mediated Host Cell Apoptosis

(2010) Jessica L. Miller et al.   PLoS Pathogens

Mycobacterium tuberculosis Eis Regulates Autophagy, Inflammation, and Cell Death through Redox-dependent Signaling

(2010) Dong-Min Shin et al.   PLoS Pathogens

Vitamin D3 Induces Autophagy in Human Monocytes/Macrophages via Cathelicidin

(2009) Jae-Min Yuk et al.   Cell Host & Microbe

Neutrophils Are the Predominant Infected Phagocytic Cells in the Airways of Patients With Active Pulmonary TB

(2009) Seok-Yong Eum et al.   CHEST

ESAT-6 Inhibits Production of IFN-  by Mycobacterium tuberculosis-Responsive Human T Cells

(2009) X. Wang et al.   JOURNAL OF IMMUNOLOGY

Mycobacterium tuberculosis evades macrophage defenses by inhibiting plasma membrane repair

(2009) Maziar Divangahi et al.   NATURE IMMUNOLOGY

Innate and adaptive immune responses to human Mycobacterium tuberculosis infection

(2009) Ramakrishna Vankayalapati et al.   TUBERCULOSIS

High granulocyte/lymphocyte ratio and paucity of NKT cells defines TB disease in a TB-endemic setting

(2009) Jayne S. Sutherland et al.   TUBERCULOSIS

Autophagy Gene Variant IRGM −261T Contributes to Protection from Tuberculosis Caused by Mycobacterium tuberculosis but Not by M. africanum Strains

(2009) Christopher D. Intemann et al.   PLoS Pathogens

Mycobacterium tuberculosis Virulence Is Mediated by PtpA Dephosphorylation of Human Vacuolar Protein Sorting 33B

(2008) Horacio Bach et al.   Cell Host & Microbe

The ΔfbpA mutant derived from Mycobacterium tuberculosis H37Rv has an enhanced susceptibility to intracellular antimicrobial oxidative mechanisms, undergoes limited phagosome maturation and activates macrophages and dendritic cells

(2008) Muralidhar K. Katti et al.   CELLULAR MICROBIOLOGY

Incorporation of Mycobacterium tuberculosis Lipoarabinomannan into Macrophage Membrane Rafts Is a Prerequisite for the Phagosomal Maturation Block

(2008) A. Welin et al.   INFECTION AND IMMUNITY

Low serum vitamin D levels and tuberculosis: a systematic review and meta-analysis

(2008) K. E Nnoaham et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Tuberculosis and latent tuberculosis infection in close contacts of people with pulmonary tuberculosis in low-income and middle-income countries: a systematic review and meta-analysis

(2008) Janina Morrison et al.   LANCET INFECTIOUS DISEASES