Continuous microfluidic assembly of biodegradable poly(beta-amino ester)/DNA nanoparticles for enhanced gene delivery

Quantification of cellular and nuclear uptake rates of polymeric gene delivery nanoparticles and DNA plasmids via flow cytometry

(2016) Corey J. Bishop et al.   Acta Biomaterialia

Non-virally engineered human adipose mesenchymal stem cells produce BMP4, target brain tumors, and extend survival

(2016) Antonella Mangraviti et al.   BIOMATERIALS

Nanoparticle-mediated transcriptional modification enhances neuronal differentiation of human neural stem cells following transplantation in rat brain

(2016) Xiaowei Li et al.   BIOMATERIALS

Modular degradable dendrimers enable small RNAs to extend survival in an aggressive liver cancer model

(2016) Kejin Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Polymeric Nanoparticles for Nonviral Gene Therapy Extend Brain Tumor Survival in Vivo

(2015) Antonella Mangraviti et al.   ACS Nano

In vivo delivery of miRNAs for cancer therapy: Challenges and strategies

(2015) Yunching Chen et al.   ADVANCED DRUG DELIVERY REVIEWS

Targeted polymeric nanoparticles for cancer gene therapy

(2015) Jayoung Kim et al.   JOURNAL OF DRUG TARGETING

Highly compacted biodegradable DNA nanoparticles capable of overcoming the mucus barrier for inhaled lung gene therapy

(2015) Panagiotis Mastorakos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bioreducible Cationic Polymer-Based Nanoparticles for Efficient and Environmentally Triggered Cytoplasmic siRNA Delivery to Primary Human Brain Cancer Cells

(2014) Kristen L. Kozielski et al.   ACS Nano

Biodegradable Polymeric Nanoparticles Show High Efficacy and Specificity at DNA Delivery to Human Glioblastoma in Vitro and in Vivo

(2014) Hugo Guerrero-Cázares et al.   ACS Nano

Shape-Controlled Synthesis of Hybrid Nanomaterials via Three-Dimensional Hydrodynamic Focusing

(2014) Mengqian Lu et al.   ACS Nano

Ultra-High Throughput Synthesis of Nanoparticles with Homogeneous Size Distribution Using a Coaxial Turbulent Jet Mixer

(2014) Jong-Min Lim et al.   ACS Nano

Microfluidic Methods for Non-Viral Gene Delivery

(2014) Wing-Fu Lai   CURRENT GENE THERAPY

Direct Interrogation of DNA Content Distribution in Nanoparticles by a Novel Microfluidics-Based Single-Particle Analysis

(2014) Cyrus W. Beh et al.   NANO LETTERS

Lipid nanocapsules functionalized with polyethyleneimine for plasmid DNA and drug co-delivery and cell imaging

(2014) Nadia Skandrani et al.   Nanoscale

In vivo endothelial siRNA delivery using polymeric nanoparticles with low molecular weight

(2014) James E. Dahlman et al.   Nature Nanotechnology

Non-viral vectors for gene-based therapy

(2014) Hao Yin et al.   NATURE REVIEWS GENETICS

Microfluidic Platform for Combinatorial Synthesis and Optimization of Targeted Nanoparticles for Cancer Therapy

(2013) Pedro M. Valencia et al.   ACS Nano

Three-Dimensional Hydrodynamic Focusing Method for Polyplex Synthesis

(2013) Mengqian Lu et al.   ACS Nano

Differential Polymer Structure Tunes Mechanism of Cellular Uptake and Transfection Routes of Poly(β-amino ester) Polyplexes in Human Breast Cancer Cells

(2013) Jayoung Kim et al.   BIOCONJUGATE CHEMISTRY

Student award winner in the Ph.D. category for the 2013 society for biomaterials annual meeting and exposition, april 10-13, 2013, Boston, Massachusetts

(2013) Stephany Y. Tzeng et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Quick-and-clean article figures with FigureJ

(2013) J. MUTTERER et al.   JOURNAL OF MICROSCOPY

Large-scale droplet production in microfluidic devices—an industrial perspective

(2013) Christian Holtze   JOURNAL OF PHYSICS D-APPLIED PHYSICS

Poly( -amino ester) Nanoparticle Delivery of TP53 Has Activity against Small Cell Lung Cancer In Vitro and In Vivo

(2013) C. D. Kamat et al.   MOLECULAR CANCER THERAPEUTICS

Microfluidic Preparation of Polymer-Nucleic Acid Nanocomplexes Improves Nonviral Gene Transfer

(2013) Christopher L. Grigsby et al.   Scientific Reports

Optimising the self-assembly of siRNA loaded PEG-PCL-lPEI nano-carriers employing different preparation techniques

(2012) Thomas Endres et al.   JOURNAL OF CONTROLLED RELEASE

Optimized preparation of pDNA/poly(ethylene imine) polyplexes using a microfluidic system

(2012) Heiko Debus et al.   LAB ON A CHIP

Uptake and Transfection with Polymeric Nanoparticles Are Dependent on Polymer End-Group Structure, but Largely Independent of Nanoparticle Physical and Chemical Properties

(2012) Joel C. Sunshine et al.   MOLECULAR PHARMACEUTICS

Microfluidic technologies for accelerating the clinical translation of nanoparticles

(2012) Pedro M. Valencia et al.   Nature Nanotechnology

Poly(β-Amino Ester)-Nanoparticle Mediated Transfection of Retinal Pigment Epithelial Cells In Vitro and In Vivo

(2012) Joel C. Sunshine et al.   PLoS One

Subtle Changes to Polymer Structure and Degradation Mechanism Enable Highly Effective Nanoparticles for siRNA and DNA Delivery to Human Brain Cancer

(2012) Stephany Y. Tzeng et al.   Advanced Healthcare Materials

Effects of Base Polymer Hydrophobicity and End-Group Modification on Polymeric Gene Delivery

(2011) Joel C. Sunshine et al.   BIOMACROMOLECULES

Non-viral gene delivery nanoparticles based on Poly(β-amino esters) for treatment of glioblastoma

(2011) Stephany Y. Tzeng et al.   BIOMATERIALS

A Novel Assay for Quantifying the Number of Plasmids Encapsulated by Polymer Nanoparticles

(2011) Nupura S. Bhise et al.   Small

Inertial microfluidics

(2009) Dino Di Carlo   LAB ON A CHIP

Single-layer planar on-chip flow cytometer using microfluidic drifting based three-dimensional (3D) hydrodynamic focusing

(2009) Xiaole Mao et al.   LAB ON A CHIP

The convergence of quantum-dot-mediated fluorescence resonance energy transfer and microfluidics for monitoring DNA polyplex self-assembly in real time

(2009) Yi-Ping Ho et al.   NANOTECHNOLOGY

A Combinatorial Polymer Library Approach Yields Insight into Nonviral Gene Delivery

(2008) Jordan J. Green et al.   ACCOUNTS OF CHEMICAL RESEARCH

Nanoparticles for Gene Transfer to Human Embryonic Stem Cell Colonies

(2008) Jordan J. Green et al.   NANO LETTERS

Microfluidic Platform for Controlled Synthesis of Polymeric Nanoparticles

(2008) Rohit Karnik et al.   NANO LETTERS

Prediction of diffusion coefficients of plasmids

(2007) D.M.F. Prazeres   BIOTECHNOLOGY AND BIOENGINEERING