Impact of aromaticity on anticancer activity of polypyridyl ruthenium(II) complexes: synthesis, structure, DNA/protein binding, lipophilicity and anticancer activity

Highly water-soluble ruthenium(II) terpyridine coordination compounds form stable adducts with blood-borne metal transporting proteins

(2018) Marija Nišavić et al.   Arabian Journal of Chemistry

New 4′-(4-chlorophenyl)-2,2′:6′,2″-terpyridine ruthenium(II) complexes: Synthesis, characterization, interaction with DNA/BSA and cytotoxicity studies

(2017) Milan M. Milutinović et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

DNA binding properties, histidine interaction and cytotoxicity studies of water soluble ruthenium(ii) terpyridine complexes

(2016) Dejan Lazić et al.   DALTON TRANSACTIONS

Chelidonium majus crude extract inhibits migration and induces cell cycle arrest and apoptosis in tumor cell lines

(2016) Milena Deljanin et al.   JOURNAL OF ETHNOPHARMACOLOGY

Chrysin Induces Apoptosis in Peripheral Blood Lymphocytes Isolated from Human Chronic Lymphocytic Leukemia

(2015) Milan Zaric et al.   Anti-Cancer Agents in Medicinal Chemistry

Mechanism of the reactions of ruthenium(II) polypyridyl complexes with thiourea, sulfur-containing amino acids and nitrogen-containing heterocycles

(2015) Ana Rilak et al.   POLYHEDRON

Effect of radiation on cytotoxicity, apoptosis and cell cycle arrest of human osteosarcoma MG-63 induced by a ruthenium(II) complex

(2015) Si-Hong Liu et al.   SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

SHELXT– Integrated space-group and crystal-structure determination

(2015) George M. Sheldrick   Acta Crystallographica A-Foundation and Advances

Crystal structure refinement withSHELXL

(2015) George M. Sheldrick   Acta Crystallographica Section C-Structural Chemistry

Mixed-ligand ruthenium polypyridyl complexes as apoptosis inducers in cancer cells, the cellular translocation and the important role of ROS-mediated signaling

(2014) Zhennan Zhao et al.   DALTON TRANSACTIONS

New Water-Soluble Ruthenium(II) Terpyridine Complexes for Anticancer Activity: Synthesis, Characterization, Activation Kinetics, and Interaction with Guanine Derivatives

(2014) Ana Rilak et al.   INORGANIC CHEMISTRY

Cephalochromin Induces G0/G1 Cell Cycle Arrest and Apoptosis in A549 Human Non-Small-Cell Lung Cancer Cells by Inflicting Mitochondrial Disruption

(2014) Che-Jen Hsiao et al.   JOURNAL OF NATURAL PRODUCTS

NKP-1339, the first ruthenium-based anticancer drug on the edge to clinical application

(2014) Robert Trondl et al.   Chemical Science

Exploration of the medical periodic table: towards new targets

(2013) Nicolas P. E. Barry et al.   CHEMICAL COMMUNICATIONS

Quinolones and non-steroidal anti-inflammatory drugs interacting with copper(ii), nickel(ii), cobalt(ii) and zinc(ii): structural features, biological evaluation and perspectives

(2013) George Psomas et al.   DALTON TRANSACTIONS

Phenanthroline ligands are biologically more active than their corresponding ruthenium(ii) arene complexes

(2013) Jesús Valladolid et al.   DALTON TRANSACTIONS

Enzyme inhibition by metal complexes: concepts, strategies and applications

(2013) Kelly J. Kilpin et al.   Chemical Science

Factors that influence the antiproliferative activity of half sandwich RuII–[9]aneS3 coordination compounds: activation kinetics and interaction with guanine derivatives

(2012) Ana Rilak et al.   DALTON TRANSACTIONS

First Palladium(II) and Platinum(II) Complexes from Employment of 2,6-Diacetylpyridine Dioxime: Synthesis, Structural and Spectroscopic Characterization, and Biological Evaluation

(2012) Evangelia S. Koumousi et al.   INORGANIC CHEMISTRY

WinGXandORTEP for Windows: an update

(2012) Louis J. Farrugia   JOURNAL OF APPLIED CRYSTALLOGRAPHY

DNA-binding and cleavage activity of polypyridyl ruthenium(II) complexes

(2012) Mohan N. Patel et al.   JOURNAL OF COORDINATION CHEMISTRY

First- and second-generation quinolone antibacterial drugs interacting with zinc(II): Structure and biological perspectives

(2012) Alketa Tarushi et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Library of second-generation cycloruthenated compounds and evaluation of their biological properties as potential anticancer drugs: Passing the nanomolar barrier

(2011) Ludivine Fetzer et al.   DALTON TRANSACTIONS

Interaction of Zn(ii) with quinolone drugs: Structure and biological evaluation

(2011) Alketa Tarushi et al.   DALTON TRANSACTIONS

Metal-based antitumour drugs in the post-genomic era: what comes next?

(2011) Gianni Sava et al.   DALTON TRANSACTIONS

Synthesis, DNA-binding and topoisomerase inhibitory activity of ruthenium(II) polypyridyl complexes

(2011) Ke-Jie Du et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Approaching tumour therapy beyond platinum drugs

(2011) A. Bergamo et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Kinetics and mechanism of the reactions of Ru(II)–arene complex with some biologically relevant ligands

(2011) Ana Rilak et al.   POLYHEDRON

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Ruthenium-based chemotherapeutics: are they ready for prime time?

(2010) Emmanuel S. Antonarakis et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Synthesis of ruthenium(II) complexes and characterization of their cytotoxicity in vitro, apoptosis, DNA-binding and antioxidant activity

(2010) Yun-Jun Liu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Organometallic ruthenium-based antitumor compounds with novel modes of action

(2010) Wee Han Ang et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

Ruthenium(II) Arene Anticancer Complexes with Redox-Active Diamine Ligands

(2009) Tijana Bugarcic et al.   INORGANIC CHEMISTRY

Zinc complexes of the antibacterial drug oxolinic acid: Structure and DNA-binding properties

(2009) Alketa Tarushi et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Medicinal Organometallic Chemistry: Designing Metal Arene Complexes as Anticancer Agents

(2008) Anna F. A. Peacock et al.   Chemistry-An Asian Journal

Phenanthroline Derivatives with Improved Selectivity as DNA-Targeting Anticancer or Antimicrobial Drugs

(2008) Sudeshna Roy et al.   ChemMedChem

New trends for metal complexes with anticancer activity

(2008) Pieter CA Bruijnincx et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Synthesis, crystal structure and interaction with DNA and HSA of (N,N′-dibenzylethane-1,2-diamine) transition metal complexes

(2008) Shan-Shan Wu et al.   JOURNAL OF INORGANIC BIOCHEMISTRY