Quantitative microspectroscopic imaging reveals viral and cellular RNA helicase interactions in live cells

Quaternary structures of opsin in live cells revealed by FRET spectrometry

(2016) A. K. Mishra et al.   BIOCHEMICAL JOURNAL

Fully quantified spectral imaging reveals in vivo membrane protein interactions

(2016) Christopher King et al.   Integrative Biology

Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5

(2016) Emiko Uchikawa et al.   MOLECULAR CELL

Comparative analysis of viral RNA signatures on different RIG-I-like receptors

(2016) Raul Y Sanchez David et al.   eLife

The sigma-1 receptors are present in monomeric and oligomeric forms in living cells in the presence and absence of ligands

(2015) Ashish K. Mishra et al.   BIOCHEMICAL JOURNAL

Experimental Verification of the Kinetic Theory of FRET Using Optical Microspectroscopy and Obligate Oligomers

(2015) Suparna Patowary et al.   BIOPHYSICAL JOURNAL

LGP2 synergy with MDA5 in RLR-mediated RNA recognition and antiviral signaling

(2015) Annie M. Bruns et al.   CYTOKINE

MAVS Coordination of Antiviral Innate Immunity

(2015) Christine Vazquez et al.   JOURNAL OF VIROLOGY

Structure of the eukaryotic MCM complex at 3.8 Å

(2015) Ningning Li et al.   NATURE

Emerging complexity and new roles for the RIG-I-like receptors in innate antiviral immunity

(2015) John S. Errett et al.   VIROLOGICA SINICA

An evolving arsenal: viral RNA detection by RIG-I-like receptors

(2014) Megan E Fitzgerald et al.   CURRENT OPINION IN MICROBIOLOGY

Antiviral RNA recognition and assembly by RLR family innate immune sensors

(2014) Annie M. Bruns et al.   CYTOKINE & GROWTH FACTOR REVIEWS

MDA5 and LGP2: Accomplices and Antagonists of Antiviral Signal Transduction

(2014) K. R. Rodriguez et al.   JOURNAL OF VIROLOGY

The Innate Immune Sensor LGP2 Activates Antiviral Signaling by Regulating MDA5-RNA Interaction and Filament Assembly

(2014) Annie M. Bruns et al.   MOLECULAR CELL

Molecular Imprinting as a Signal-Activation Mechanism of the Viral RNA Sensor RIG-I

(2014) Bin Wu et al.   MOLECULAR CELL

RIG-I Self-Oligomerization Is Either Dispensable or Very Transient for Signal Transduction

(2014) Jade Louber et al.   PLoS One

Identification of an LGP2-associated MDA5 agonist in picornavirus-infected cells

(2014) Safia Deddouche et al.   eLife

Pattern Recognition and Signaling Mechanisms of RIG-I and MDA5

(2014) Stephanie Reikine et al.   Frontiers in Immunology

The muscarinic M3acetylcholine receptor exists as two differently sized complexes at the plasma membrane

(2013) Suparna Patowary et al.   BIOCHEMICAL JOURNAL

FRET Spectrometry: A New Tool for the Determination of Protein Quaternary Structure in Living Cells

(2013) Valerică Raicu et al.   BIOPHYSICAL JOURNAL

ATPase-driven oligomerization of RIG-I on RNA allows optimal activation of type-I interferon

(2013) Jenish R Patel et al.   EMBO REPORTS

Development and Experimental Testing of an Optical Micro-Spectroscopic Technique Incorporating True Line-Scan Excitation

(2013) Gabriel Biener et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

RIG-I Forms Signaling-Competent Filaments in an ATP-Dependent, Ubiquitin-Independent Manner

(2013) Alys Peisley et al.   MOLECULAR CELL

Regulation of hepatic innate immunity by hepatitis C virus

(2013) Stacy M Horner et al.   NATURE MEDICINE

Rig-I regulates NF- B activity through binding to Nf- b1 3'-UTR mRNA

(2013) H.-X. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Hexameric Helicase DnaB Adopts a Nonplanar Conformation during Translocation

(2012) Ornchuma Itsathitphaisarn et al.   CELL

MDA5 cooperatively forms dimers and ATP-sensitive filaments upon binding double-stranded RNA

(2012) Ian C Berke et al.   EMBO JOURNAL

Superfamily 2 helicases

(2012) Alicia et al.   Frontiers in Bioscience-Landmark

Determination of the quaternary structure of a bacterial ATP-binding cassette (ABC) transporter in living cells

(2012) Deo R. Singh et al.   Integrative Biology

ATP Hydrolysis Enhances RNA Recognition and Antiviral Signal Transduction by the Innate Immune Sensor, Laboratory of Genetics and Physiology 2 (LGP2)

(2012) Annie M. Bruns et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Control of Innate Immune Signaling and Membrane Targeting by the Hepatitis C Virus NS3/4A Protease Are Governed by the NS3 Helix  0

(2012) S. M. Horner et al.   JOURNAL OF VIROLOGY

MAVS Forms Functional Prion-like Aggregates to Activate and Propagate Antiviral Innate Immune Response

(2011) Fajian Hou et al.   CELL

Activation of RIG-I-like receptor signal transduction

(2011) Annie M. Bruns et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

In vivo Quantification of G Protein Coupled Receptor Interactions using Spectrally Resolved Two-photon Microscopy

(2011) Michael Stoneman et al.   Jove-Journal of Visualized Experiments

RIG-I Detects Viral Genomic RNA during Negative-Strand RNA Virus Infection

(2010) Jan Rehwinkel et al.   CELL

Real-time imaging of hepatitis C virus infection using a fluorescent cell-based reporter system

(2010) Christopher T Jones et al.   NATURE BIOTECHNOLOGY

Three conformational snapshots of the hepatitis C virus NS3 helicase reveal a ratchet translocation mechanism

(2010) M. Gu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The fluorescent protein palette: tools for cellular imaging

(2009) Richard N. Day et al.   CHEMICAL SOCIETY REVIEWS

Fuel Specificity of the Hepatitis C Virus NS3 Helicase

(2009) Craig A. Belon et al.   JOURNAL OF MOLECULAR BIOLOGY

Determination of supramolecular structure and spatial distribution of protein complexes in living cells

(2009) Valerica Raicu et al.   Nature Photonics

Hepatitis C Virus NS3 Helicase Forms Oligomeric Structures That Exhibit Optimal DNA Unwinding Activityin Vitro

(2008) Bartek Sikora et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NS3 Helicase from the Hepatitis C Virus Can Function as a Monomer or Oligomer Depending on Enzyme and Substrate Concentrations

(2008) Thomas A. Jennings et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure and Function of LGP2, a DEX(D/H) Helicase That Regulates the Innate Immunity Response

(2008) Ayaluru Murali et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Analysis of the Evolutionary Forces in an Immunodominant CD8 Epitope in Hepatitis C Virus at a Population Level

(2008) C. Neumann-Haefelin et al.   JOURNAL OF VIROLOGY

MAVS Dimer Is a Crucial Signaling Component of Innate Immunity and the Target of Hepatitis C Virus NS3/4A Protease

(2008) M. Baril et al.   JOURNAL OF VIROLOGY