Pseudouridine Modification Inhibits Muscleblind-like 1 (MBNL1) Binding to CCUG Repeats and Minimally Structured RNA through Reduced RNA Flexibility
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Title
Pseudouridine Modification Inhibits Muscleblind-like 1 (MBNL1) Binding to CCUG Repeats and Minimally Structured RNA through Reduced RNA Flexibility
Authors
Keywords
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Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 292, Issue 10, Pages 4350-4357
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2017-01-28
DOI
10.1074/jbc.m116.770768
References
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- Thermodynamic contribution and nearest-neighbor parameters of pseudouridine-adenosine base pairs in oligoribonucleotides
- (2013) G. A. Hudson et al. RNA
- Transcriptome-wide Regulation of Pre-mRNA Splicing and mRNA Localization by Muscleblind Proteins
- (2012) Eric T. Wang et al. CELL
- The four Zn fingers of MBNL1 provide a flexible platform for recognition of its RNA binding elements
- (2011) Danielle Cass et al. BMC MOLECULAR BIOLOGY
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- Misregulation of miR-1 processing is associated with heart defects in myotonic dystrophy
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- MBNL1 binds GC motifs embedded in pyrimidines to regulate alternative splicing
- (2010) Emily S. Goers et al. NUCLEIC ACIDS RESEARCH
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- GROMACS 4: Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation
- (2008) Berk Hess et al. Journal of Chemical Theory and Computation
- Structural insights into RNA recognition by the alternative-splicing regulator muscleblind-like MBNL1
- (2008) Marianna Teplova et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
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