MicroRNA-302a suppresses influenza A virus–stimulated interferon regulatory factor-5 expression and cytokine storm induction

Genistein Protects Against Ox-LDL-Induced Inflammation Through MicroRNA-155/SOCS1-Mediated Repression of NF-ĸB Signaling Pathway in HUVECs

(2017) Huaping Zhang et al.   INFLAMMATION

Inducible CYP4F12 enhances Hepatitis C virus infection via association with viral nonstructural protein 5B

(2016) Sheng-Li Zhu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Inducible Major Vault Protein Plays a Pivotal Role in Double-Stranded RNA– or Virus-Induced Proinflammatory Response

(2016) Nanfang Peng et al.   JOURNAL OF IMMUNOLOGY

Generation of influenza A viruses as live but replication-incompetent virus vaccines

(2016) L. Si et al.   SCIENCE

Development of a more efficient hepatitis B virus vaccine by targeting hepatitis B virus preS to dendritic cells

(2016) Mingzhen Jing et al.   VACCINE

Reprogramming macrophage orientation by microRNA 146b targeting transcription factor IRF5

(2016) Liang Peng et al.   EBioMedicine

Loss of RACK1 Promotes Metastasis of Gastric Cancer by Inducing a miR-302c/IL8 Signaling Loop

(2015) Ling Chen et al.   CANCER RESEARCH

The cytokine storm of severe influenza and development of immunomodulatory therapy

(2015) Qiang Liu et al.   Cellular & Molecular Immunology

Mir-302c mediates influenza A virus-induced IFNβ expression by targeting NF-κB inducing kinase

(2015) Shulin Gui et al.   FEBS LETTERS

Human hepatitis B virus surface and e antigens inhibit major vault protein signaling in interferon induction pathways

(2015) Shi Liu et al.   JOURNAL OF HEPATOLOGY

TLR8 SensesStaphylococcus aureusRNA in Human Primary Monocytes and Macrophages and Induces IFN-β Production via a TAK1–IKKβ–IRF5 Signaling Pathway

(2015) Bjarte Bergstrøm et al.   JOURNAL OF IMMUNOLOGY

Attenuation of Cardiac Dysfunction in Polymicrobial Sepsis by MicroRNA-146a Is Mediated via Targeting of IRAK1 and TRAF6 Expression

(2015) Ming Gao et al.   JOURNAL OF IMMUNOLOGY

Regulatory roles of c-jun in H5N1 influenza virus replication and host inflammation

(2014) Jingjing Xie et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Mapping the innate signaling cascade essential for cytokine storm during influenza virus infection

(2014) J. R. Teijaro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IKKβ is an IRF5 kinase that instigates inflammation

(2014) Junyao Ren et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Influenza A virus uses the aggresome processing machinery for host cell entry

(2014) Indranil Banerjee et al.   SCIENCE

Suppressor of Cytokine Signaling 4 (SOCS4) Protects against Severe Cytokine Storm and Enhances Viral Clearance during Influenza Infection

(2014) Lukasz Kedzierski et al.   PLoS Pathogens

Major vault protein: A virus-induced host factor against viral replication through the induction of type-I interferon

(2012) Shi Liu et al.   HEPATOLOGY

Engineering H5N1 avian influenza viruses to study human adaptation

(2012) David M. Morens et al.   NATURE

Cross-interference of RLR and TLR signaling pathways modulates antibacterial T cell responses

(2012) Hideo Negishi et al.   NATURE IMMUNOLOGY

Spontaneous mutation of the Dock2 gene in Irf5-/- mice complicates interpretation of type I interferon production and antibody responses

(2012) W. E. Purtha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The microRNA-302-367 cluster suppresses the proliferation of cervical carcinoma cells through the novel target AKT1

(2012) N. Cai et al.   RNA

A New Shield for a Cytokine Storm

(2011) Akiko Iwasaki et al.   CELL

Endothelial Cells Are Central Orchestrators of Cytokine Amplification during Influenza Virus Infection

(2011) John R. Teijaro et al.   CELL

IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses

(2011) Thomas Krausgruber et al.   NATURE IMMUNOLOGY

Differential Requirement of Histone Acetylase and Deacetylase Activities for IRF5-Mediated Proinflammatory Cytokine Expression

(2010) D. Feng et al.   JOURNAL OF IMMUNOLOGY

Modulation of Interferon Regulatory Factor 5 Activities by the Kaposi Sarcoma-Associated Herpesvirus-Encoded Viral Interferon Regulatory Factor 3 Contributes to Immune Evasion and Lytic Induction

(2010) Xiaohui Bi et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Cellular MicroRNAs Inhibit Replication of the H1N1 Influenza A Virus in Infected Cells

(2010) L. Song et al.   JOURNAL OF VIROLOGY

A dicer-independent miRNA biogenesis pathway that requires Ago catalysis

(2010) Sihem Cheloufi et al.   NATURE

Calming the cytokine storm

(2010) Charlotte Harrison   NATURE REVIEWS DRUG DISCOVERY

Essential Impact of NF- B Signaling on the H5N1 Influenza A Virus-Induced Transcriptome

(2009) M. Schmolke et al.   JOURNAL OF IMMUNOLOGY

NF- B Signaling Differentially Regulates Influenza Virus RNA Synthesis

(2008) N. Kumar et al.   JOURNAL OF VIROLOGY

Functional Regulation of MyD88-Activated Interferon Regulatory Factor 5 by K63-Linked Polyubiquitination

(2008) M. Y. Balkhi et al.   MOLECULAR AND CELLULAR BIOLOGY

Embryonic Stem Cell-Specific miR302-367 Cluster: Human Gene Structure and Functional Characterization of Its Core Promoter

(2008) A. Barroso-delJesus et al.   MOLECULAR AND CELLULAR BIOLOGY

Oct4/Sox2-Regulated miR-302 Targets Cyclin D1 in Human Embryonic Stem Cells

(2008) D. A. Greer Card et al.   MOLECULAR AND CELLULAR BIOLOGY