β-Adrenergic induction of lipolysis in hepatocytes is inhibited by ethanol exposure

ATGL Promotes Autophagy/Lipophagy via SIRT1 to Control Hepatic Lipid Droplet Catabolism

(2017) Aishwarya Sathyanarayan et al.   Cell Reports

A novel Rab10-EHBP1-EHD2 complex essential for the autophagic engulfment of lipid droplets

(2016) Z. Li et al.   Science Advances

Morphologically and Functionally Distinct Lipid Droplet Subpopulations

(2016) Shuyan Zhang et al.   Scientific Reports

Acetaldehyde accelerates HCV-induced impairment of innate immunity by suppressing methylation reactions in liver cells

(2015) Murali Ganesan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

ATGL-Catalyzed Lipolysis Regulates SIRT1 to Control PGC-1α/PPAR-α Signaling

(2015) Salmaan Ahmed Khan et al.   DIABETES

The small GTPase Rab7 as a central regulator of hepatocellular lipophagy

(2015) Barbara Schroeder et al.   HEPATOLOGY

Perilipin 5 improves hepatic lipotoxicity by inhibiting lipolysis

(2015) Chao Wang et al.   HEPATOLOGY

A well-oiled machine

(2014) Ryan J Schulze et al.   Autophagy

Absence of Perilipin 2 Prevents Hepatic Steatosis, Glucose Intolerance and Ceramide Accumulation in Alcohol-Fed Mice

(2014) Rotonya M. Carr et al.   PLoS One

β-Adrenergic Agonist and Antagonist Regulation of Autophagy in HepG2 Cells, Primary Mouse Hepatocytes, and Mouse Liver

(2014) Benjamin L. Farah et al.   PLoS One

Rab GTPases Associate with Isolated Lipid Droplets (LDs) and Show Altered Content After Ethanol Administration: Potential Role in Alcohol-Impaired LD Metabolism

(2013) Karuna Rasineni et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

β-adrenergic receptor-stimulated lipolysis requires the RAB7-mediated autolysosomal lipid degradation

(2013) Analyn Lizaso et al.   Autophagy

Caffeine stimulates hepatic lipid metabolism by the autophagy-lysosomal pathway in mice

(2013) Rohit A. Sinha et al.   HEPATOLOGY

Lipid droplet breakdown requires Dynamin 2 for vesiculation of autolysosomal tubules in hepatocytes

(2013) Ryan J. Schulze et al.   JOURNAL OF CELL BIOLOGY

The G0/G1 Switch Gene 2 Is an Important Regulator of Hepatic Triglyceride Metabolism

(2013) Yinfang Wang et al.   PLoS One

Lipid Droplets and Cellular Lipid Metabolism

(2012) Tobias C. Walther et al.   Annual Review of Biochemistry

Identification and Functional Characterization of Protein Kinase A Phosphorylation Sites in the Major Lipolytic Protein, Adipose Triglyceride Lipase

(2012) Joanne Pagnon et al.   ENDOCRINOLOGY

Hepatic ATGL knockdown uncouples glucose intolerance from liver TAG accumulation

(2012) Kuok Teong Ong et al.   FASEB JOURNAL

Role of β-adrenergic receptors in regulation of hepatic fat accumulation during aging

(2012) Paramita M Ghosh et al.   JOURNAL OF ENDOCRINOLOGY

Role of ceramides in nonalcoholic fatty liver disease

(2012) Mangesh Pagadala et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

The metabolic footprint of aging in mice

(2011) Riekelt H. Houtkooper et al.   Scientific Reports

Inhibitory effect of ethanol on AMPK phosphorylation is mediated in part through elevated ceramide levels

(2010) Suthat Liangpunsakul et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

The G0/G1 Switch Gene 2 Regulates Adipose Lipolysis through Association with Adipose Triglyceride Lipase

(2010) Xingyuan Yang et al.   Cell Metabolism

Adipose triglyceride lipase is a major hepatic lipase that regulates triacylglycerol turnover and fatty acid signaling and partitioning

(2010) Kuok Teong Ong et al.   HEPATOLOGY

Interactions of Perilipin-5 (Plin5) with Adipose Triglyceride Lipase

(2010) James G. Granneman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Visualization of PKA activity in plasma membrane microdomains

(2010) Charlene Depry et al.   Molecular BioSystems

Alcoholic Liver Disease

(2009) Robert S O’Shea et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

PAT proteins, an ancient family of lipid droplet proteins that regulate cellular lipid stores

(2009) Perry E. Bickel et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Contribution of Adipose Triglyceride Lipase and Hormone-sensitive Lipase to Lipolysis in hMADS Adipocytes

(2009) Véronic Bezaire et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of Hormone-sensitive Lipase Requires Two Steps, Protein Phosphorylation and Binding to the PAT-1 Domain of Lipid Droplet Coat Proteins

(2009) Hong Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Perilipin Controls Lipolysis by Regulating the Interactions of AB-hydrolase Containing 5 (Abhd5) and Adipose Triglyceride Lipase (Atgl)

(2009) James G. Granneman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipid droplets at a glance

(2009) Y. Guo et al.   JOURNAL OF CELL SCIENCE

Coatomer-dependent protein delivery to lipid droplets

(2009) K. G. Soni et al.   JOURNAL OF CELL SCIENCE

Autophagy regulates lipid metabolism

(2009) Rajat Singh et al.   NATURE

Differential pattern of lipid droplet-associated proteins andde novoperilipin expression in hepatocyte steatogenesis

(2008) Beate Katharina Straub et al.   HEPATOLOGY

Hepatic Overexpression of Hormone-sensitive Lipase and Adipose Triglyceride Lipase Promotes Fatty Acid Oxidation, Stimulates Direct Release of Free Fatty Acids, and Ameliorates Steatosis

(2008) Brendan N. Reid et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hormone-sensitive lipase is involved in hepatic cholesteryl ester hydrolysis

(2008) Motohiro Sekiya et al.   JOURNAL OF LIPID RESEARCH