Skeletal overgrowth-causing mutations mimic an allosterically activated conformation of guanylyl cyclase-B that is inhibited by 2,4,6,-trinitrophenyl ATP

Dephosphorylation of juxtamembrane serines and threonines of the NPR2 guanylyl cyclase is required for rapid resumption of oocyte meiosis in response to luteinizing hormone

(2016) Leia C. Shuhaibar et al.   DEVELOPMENTAL BIOLOGY

Catalytically Active Guanylyl Cyclase B Requires Endoplasmic Reticulum-mediated Glycosylation, and Mutations That Inhibit This Process Cause Dwarfism

(2016) Deborah M. Dickey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Physiology of Membrane Guanylyl Cyclase Receptors

(2016) Michaela Kuhn   PHYSIOLOGICAL REVIEWS

Acromesomelic dysplasia, type maroteaux caused by novel loss-of-function mutations of the NPR2 gene: Three case reports

(2015) Wei Wang et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Heterozygous Mutations in Natriuretic Peptide Receptor-B (NPR2) Gene as a Cause of Short Stature

(2015) Sophie R. Wang et al.   HUMAN MUTATION

Dephosphorylation and inactivation of NPR2 guanylyl cyclase in granulosa cells contributes to the LH-induced decrease in cGMP that causes resumption of meiosis in rat oocytes

(2014) J. R. Egbert et al.   DEVELOPMENT

Overgrowth syndrome associated with a gain-of-function mutation of the natriuretic peptide receptor 2 (NPR2) gene

(2013) Kohji Miura et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

A human skeletal overgrowth mutation increases maximal velocity and blocks desensitization of guanylyl cyclase-B

(2013) Jerid W. Robinson et al.   BONE

An Activating Mutation in the Kinase Homology Domain of the Natriuretic Peptide Receptor-2 Causes Extremely Tall Stature Without Skeletal Deformities

(2013) Sabine E. Hannema et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Nucleotidyl Cyclase Activity of Particulate Guanylyl Cyclase A: Comparison with Particulate Guanylyl Cyclases E and F, Soluble Guanylyl Cyclase and Bacterial Adenylyl Cyclases Cyaa and Edema Factor

(2013) Kerstin Y. Beste et al.   PLoS One

Evaluation of the Therapeutic Potential of a CNP Analog in a Fgfr3 Mouse Model Recapitulating Achondroplasia

(2012) Florence Lorget et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A Functional Screen Provides Evidence for a Conserved, Regulatory, Juxtamembrane Phosphorylation Site in Guanylyl Cyclase A and B

(2012) Andrea R. Yoder et al.   PLoS One

An Overgrowth Disorder Associated with Excessive Production of cGMP Due to a Gain-of-Function Mutation of the Natriuretic Peptide Receptor 2 Gene

(2012) Kohji Miura et al.   PLoS One

Guanylyl Cyclases A and B Are Asymmetric Dimers That Are Allosterically Activated by ATP Binding to the Catalytic Domain

(2012) J. W. Robinson et al.   Science Signaling

Guanylyl cyclase structure, function and regulation

(2011) Lincoln R. Potter   CELLULAR SIGNALLING

Mass Spectrometric Identification of Phosphorylation Sites in Guanylyl Cyclase A and B

(2010) Andrea R. Yoder et al.   BIOCHEMISTRY

Reduced ability of C-type natriuretic peptide (CNP) to activate natriuretic peptide receptor B (NPR-B) causes dwarfism in lbab−/− mice

(2008) Andrea R. Yoder et al.   PEPTIDES