Glucocorticoid receptor signaling represses the antioxidant response by inhibiting histone acetylation mediated by the transcriptional activator NRF2

Epigenetic Regulation of the Blimp-1 Gene (Prdm1) in B Cells Involves Bach2 and Histone Deacetylase 3

(2016) Hiromu Tanaka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription

(2016) Eri H. Kobayashi et al.   Nature Communications

Alcohol dehydrogenase 3 contributes to the protection of liver from nonalcoholic steatohepatitis

(2015) Maki Goto et al.   GENES TO CELLS

The Transcription Factor Bach2 Is Phosphorylated at Multiple Sites in Murine B Cells but a Single Site Prevents Its Nuclear Localization

(2015) Ryo Ando et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tissue Specific Regulation of Glucocorticoids in Severe Obesity and the Response to Significant Weight Loss Following Bariatric Surgery (BARICORT)

(2015) C.P. Woods et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

The Mediator Subunit MED16 Transduces NRF2-Activating Signals into Antioxidant Gene Expression

(2015) Hiroki Sekine et al.   MOLECULAR AND CELLULAR BIOLOGY

NF-E2-related factor 2 promotes compensatory liver hypertrophy after portal vein branch ligation in mice

(2014) Keiichi Shirasaki et al.   HEPATOLOGY

Transcriptional enhancers: from properties to genome-wide predictions

(2014) Daria Shlyueva et al.   NATURE REVIEWS GENETICS

Inhibition of 11β-HSD1 with RO5093151 for non-alcoholic fatty liver disease: a multicentre, randomised, double-blind, placebo-controlled trial

(2014) Norbert Stefan et al.   Lancet Diabetes & Endocrinology

Evaluation and Optimization of Mass Spectrometric Settings during Data-dependent Acquisition Mode: Focus on LTQ-Orbitrap Mass Analyzers

(2013) Anastasia Kalli et al.   JOURNAL OF PROTEOME RESEARCH

Nrf2 Enhances Cholangiocyte Expansion in Pten-Deficient Livers

(2013) Keiko Taguchi et al.   MOLECULAR AND CELLULAR BIOLOGY

Notch-Nrf2 Axis: Regulation of Nrf2 Gene Expression and Cytoprotection by Notch Signaling

(2013) N. Wakabayashi et al.   MOLECULAR AND CELLULAR BIOLOGY

Genetic Activation of Nrf2 Protects against Fasting-Induced Oxidative Stress in Livers of Mice

(2013) Yu-Kun Jennifer Zhang et al.   PLoS One

Consumption of a high-fat diet rapidly exacerbates the development of fatty liver disease that occurs with chronically elevated glucocorticoids

(2012) Anna M. D'souza et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

H3K9 and H3K14 acetylation co-occur at many gene regulatory elements, while H3K14ac marks a subset of inactive inducible promoters in mouse embryonic stem cells

(2012) Krishanpal Karmodiya et al.   BMC GENOMICS

Nrf2 Redirects Glucose and Glutamine into Anabolic Pathways in Metabolic Reprogramming

(2012) Yoichiro Mitsuishi et al.   CANCER CELL

Sestrins Activate Nrf2 by Promoting p62-Dependent Autophagic Degradation of Keap1 and Prevent Oxidative Liver Damage

(2012) Soo Han Bae et al.   Cell Metabolism

Hepatic growth hormone and glucocorticoid receptor signaling in body growth, steatosis and metabolic liver cancer development

(2012) Kristina M. Mueller et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

How glucocorticoid receptors modulate the activity of other transcription factors: A scope beyond tethering

(2012) Dariusz Ratman et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Nrf2 is controlled by two distinct β-TrCP recognition motifs in its Neh6 domain, one of which can be modulated by GSK-3 activity

(2012) S Chowdhry et al.   ONCOGENE

Suppression of the Nrf2-Dependent Antioxidant Response by Glucocorticoids and 11β-HSD1-Mediated Glucocorticoid Activation in Hepatic Cells

(2012) Denise V. Kratschmar et al.   PLoS One

Carbenoxolone Treatment Ameliorated Metabolic Syndrome in WNIN/Ob Obese Rats, but Induced Severe Fat Loss and Glucose Intolerance in Lean Rats

(2012) Siva Sankara Vara Prasad Sakamuri et al.   PLoS One

Regulation of Notch1 Signaling by Nrf2: Implications for Tissue Regeneration

(2010) N. Wakabayashi et al.   Science Signaling

Enhanced expression of Nrf2 in mice attenuates the fatty liver produced by a methionine- and choline-deficient diet☆

(2010) Yu-Kun Jennifer Zhang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Staining of Proteins in Gels with Coomassie G-250 without Organic Solvent and Acetic Acid

(2010) Ann-Marie Lawrence et al.   Jove-Journal of Visualized Experiments

Deletion of nuclear factor-E2-related factor-2 leads to rapid onset and progression of nutritional steatohepatitis in mice

(2009) Hirokazu Sugimoto et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Loss of Nrf2 markedly exacerbates nonalcoholic steatohepatitis

(2009) Sudhir Chowdhry et al.   FREE RADICAL BIOLOGY AND MEDICINE

Hypersensitivity of Aryl Hydrocarbon Receptor-Deficient Mice to Lipopolysaccharide-Induced Septic Shock

(2009) H. Sekine et al.   MOLECULAR AND CELLULAR BIOLOGY

Nrf2 regulates the alternative first exons of CD36 in macrophages through specific antioxidant response elements

(2008) Atsushi Maruyama et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS