Cytochrome P450 27A1 Deficiency and Regional Differences in Brain Sterol Metabolism Cause Preferential Cholestanol Accumulation in the Cerebellum

Mapping of the Allosteric Site in Cholesterol Hydroxylase CYP46A1 for Efavirenz, a Drug That Stimulates Enzyme Activity

(2016) Kyle W. Anderson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evaluation of cholesterol metabolism in cerebrotendinous xanthomatosis

(2015) Andrea Mignarri et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Age, Sex, andAPOEε4 Effects on Memory, Brain Structure, and β-Amyloid Across the Adult Life Span

(2015) Clifford R. Jack et al.   JAMA Neurology

Retinal and Nonocular Abnormalities in Cyp27a1−/−Cyp46a1−/− Mice with Dysfunctional Metabolism of Cholesterol

(2014) Aicha Saadane et al.   AMERICAN JOURNAL OF PATHOLOGY

Pathways of cholesterol homeostasis in mouse retina responsive to dietary and pharmacologic treatments

(2014) Wenchao Zheng et al.   JOURNAL OF LIPID RESEARCH

Cerebrotendinous xanthomatosis

(2013) Ingemar Björkhem   CURRENT OPINION IN LIPIDOLOGY

Pharmacologic Stimulation of Cytochrome P450 46A1 and Cerebral Cholesterol Turnover in Mice

(2013) Natalia Mast et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Abnormal vascularization in mouse retina with dysregulated retinal cholesterol homeostasis

(2012) Saida Omarova et al.   JOURNAL OF CLINICAL INVESTIGATION

Cholesterol metabolism in neurons and astrocytes

(2011) Frank W. Pfrieger et al.   PROGRESS IN LIPID RESEARCH

Cerebrotendinous xanthomatosis: An inborn error in bile acid synthesis with defined mutations but still a challenge

(2010) Ingemar Björkhem et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

On the mechanism of accumulation of cholestanol in the brain of mice with a disruption of sterol 27-hydroxylase

(2010) Ann Båvner et al.   JOURNAL OF LIPID RESEARCH

Quantification of Cholesterol-Metabolizing P450s CYP27A1 and CYP46A1 in Neural Tissues Reveals a Lack of Enzyme−Product Correlations in Human Retina but Not Human Brain

(2010) Wei-Li Liao et al.   JOURNAL OF PROTEOME RESEARCH

Use of complementary cation and anion heavy-atom salt derivatives to solve the structure of cytochrome P450 46A1

(2008) Mark Andrew White et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Strategy combining separation of isotope-labeled unfolded proteins and matrix-assisted laser desorption/ionization mass spectrometry analysis enables quantification of a wide range of serum proteins

(2008) Wei-Li Liao et al.   ANALYTICAL BIOCHEMISTRY

Neuronal expression and subcellular localization of cholesterol 24-hydroxylase in the mouse brain

(2008) Denise M.O. Ramirez et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Cholesterol feedback: from Schoenheimer's bottle to Scap's MELADL

(2008) Michael S. Brown et al.   JOURNAL OF LIPID RESEARCH