Coupling of Insulin Secretion and Display of a Granule-resident Zinc Transporter ZnT8 on the Surface of Pancreatic Beta Cells
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Coupling of Insulin Secretion and Display of a Granule-resident Zinc Transporter ZnT8 on the Surface of Pancreatic Beta Cells
Authors
Keywords
-
Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 292, Issue 10, Pages 4034-4043
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2017-01-28
DOI
10.1074/jbc.m116.772152
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- A unique CD8+ T lymphocyte signature in pediatric type 1 diabetes
- (2016) Yamina Hamel et al. JOURNAL OF AUTOIMMUNITY
- Lipid-tuned Zinc Transport Activity of Human ZnT8 Protein Correlates with Risk for Type-2 Diabetes
- (2016) Chengfeng Merriman et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Identification of Candidate Tolerogenic CD8+T Cell Epitopes for Therapy of Type 1 Diabetes in the NOD Mouse Model
- (2016) Cailin Yu et al. Journal of Diabetes Research
- A bright monomeric green fluorescent protein derived from Branchiostoma lanceolatum
- (2013) Nathan C Shaner et al. NATURE METHODS
- ZnT8-Specific CD4+ T Cells Display Distinct Cytokine Expression Profiles between Type 1 Diabetes Patients and Healthy Adults
- (2013) Daisuke Chujo et al. PLoS One
- Islet Autoantigens: Structure, Function, Localization, and Regulation
- (2013) P. Arvan et al. Cold Spring Harbor Perspectives in Medicine
- Antigen Targets of Type 1 Diabetes Autoimmunity
- (2013) B. O. Roep et al. Cold Spring Harbor Perspectives in Medicine
- ZnT8 Is a Major CD8+ T Cell-Recognized Autoantigen in Pediatric Type 1 Diabetes
- (2012) E. Enee et al. DIABETES
- Zinc transporters and their role in the pancreatic β-cell
- (2012) Katleen Lemaire et al. Journal of Diabetes Investigation
- An Overview of a Wide Range of Functions of ZnT and Zip Zinc Transporters in the Secretory Pathway
- (2011) Taiho KAMBE BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
- T cell-driven initiation and propagation of autoimmune diabetes
- (2011) Maria Bettini et al. CURRENT OPINION IN IMMUNOLOGY
- How Does Type 1 Diabetes Develop?: The Notion of Homicide or -Cell Suicide Revisited
- (2011) M. A. Atkinson et al. DIABETES
- Human Type 1 Diabetes Is Associated with T Cell Autoimmunity to Zinc Transporter 8
- (2011) M. Dang et al. JOURNAL OF IMMUNOLOGY
- siRNA-mediated knock-down of ZnT3 and ZnT8 affects production and secretion of insulin and apoptosis in INS-1E cells
- (2010) ANDREAS B. PETERSEN et al. APMIS
- Beta cell-specific Znt8 deletion in mice causes marked defects in insulin processing, crystallisation and secretion
- (2010) N. Wijesekara et al. DIABETOLOGIA
- Acute cytokine-mediated downregulation of the zinc transporter ZnT8 alters pancreatic β-cell function
- (2010) Malek El Muayed et al. JOURNAL OF ENDOCRINOLOGY
- Downregulation of ZnT8 expression in pancreatic β-cells of diabetic mice
- (2010) Motoyuki Tamaki et al. Islets
- Insulin Storage and Glucose Homeostasis in Mice Null for the Granule Zinc Transporter ZnT8 and Studies of the Type 2 Diabetes-Associated Variants
- (2009) T. J. Nicolson et al. DIABETES
- The role of inflammation in insulitis and β-cell loss in type 1 diabetes
- (2009) Décio L. Eizirik et al. Nature Reviews Endocrinology
- Structural basis for autoregulation of the zinc transporter YiiP
- (2009) Min Lu et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Down-Regulation of ZnT8 Expression in INS-1 Rat Pancreatic Beta Cells Reduces Insulin Content and Glucose-Inducible Insulin Secretion
- (2009) Yi Fu et al. PLoS One
- Insulin crystallization depends on zinc transporter ZnT8 expression, but is not required for normal glucose homeostasis in mice
- (2009) K. Lemaire et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Investigation of Transport Mechanisms and Regulation of Intracellular Zn2+in Pancreatic α-Cells
- (2008) Armen V. Gyulkhandanyan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Diabetes-linked zinc transporter ZnT8 is a homodimeric protein expressed by distinct rodent endocrine cell types in the pancreas and other glands
- (2008) C. Murgia et al. NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now