Plasma membrane phosphatidylinositol 4-phosphate and 4,5-bisphosphate determine the distribution and function of K-Ras4B but not H-Ras proteins

Regulation of Ras signaling and function by plasma membrane microdomains

(2017) Lawrence E. Goldfinger et al.   BioScience Trends

BRET-monitoring of the dynamic changes of inositol lipid pools in living cells reveals a PKC-dependent PtdIns4P increase upon EGF and M3 receptor activation

(2016) József T. Tóth et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Ras Conformational Ensembles, Allostery, and Signaling

(2016) Shaoyong Lu et al.   CHEMICAL REVIEWS

The Continuing Mystery of Lipid Rafts

(2016) Ilya Levental et al.   JOURNAL OF MOLECULAR BIOLOGY

Recent progress on lipid lateral heterogeneity in plasma membranes: From rafts to submicrometric domains

(2016) Mélanie Carquin et al.   PROGRESS IN LIPID RESEARCH

Identification of pyrazolopyridazinones as PDEδ inhibitors

(2016) Björn Papke et al.   Nature Communications

Ras nanoclusters: Versatile lipid-based signaling platforms

(2015) Yong Zhou et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The interactions of peripheral membrane proteins with biological membranes

(2015) A.M. Whited et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Divergent Roles of CAAXMotif-signaled Posttranslational Modifications in the Regulation and Subcellular Localization of Ral GTPases

(2015) Leanna R. Gentry et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nanoscale Landscape of Phosphoinositides Revealed by Specific Pleckstrin Homology (PH) Domains Using Single-molecule Superresolution Imaging in the Plasma Membrane

(2015) Chen Ji et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of acid sphingomyelinase depletes cellular phosphatidylserine and mislocalizes K-Ras from the plasma membrane

(2015) Kwang-jin Cho et al.   MOLECULAR AND CELLULAR BIOLOGY

Ral small GTPase signaling and oncogenesis: More than just 15minutes of fame

(2014) Leanna R. Gentry et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

KRas Localizes to the Plasma Membrane by Spatial Cycles of Solubilization, Trapping and Vesicular Transport

(2014) Malte Schmick et al.   CELL

Cellular and molecular interactions of phosphoinositides and peripheral proteins

(2014) Robert V. Stahelin et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Dynamics of KRas on endosomes: involvement of acidic phospholipids in its association

(2014) Mariona Gelabert-Baldrich et al.   FASEB JOURNAL

A novel probe for phosphatidylinositol 4-phosphate reveals multiple pools beyond the Golgi

(2014) Gerald R.V. Hammond et al.   JOURNAL OF CELL BIOLOGY

Membrane raft association is a determinant of plasma membrane localization

(2014) B. B. Diaz-Rohrer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Small molecule inhibition of the KRAS–PDEδ interaction impairs oncogenic KRAS signalling

(2013) Gunther Zimmermann et al.   NATURE

A Comprehensive Survey of Ras Mutations in Cancer

(2012) I. A. Prior et al.   CANCER RESEARCH

Curvature, Lipid Packing, and Electrostatics of Membrane Organelles: Defining Cellular Territories in Determining Specificity

(2012) Joëlle Bigay et al.   DEVELOPMENTAL CELL

Staurosporines Disrupt Phosphatidylserine Trafficking and Mislocalize Ras Proteins

(2012) Kwang-jin Cho et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Acute depletion of plasma membrane phosphatidylinositol 4,5-bisphosphate impairs specific steps in endocytosis of the G-protein-coupled receptor

(2012) D. J. Toth et al.   JOURNAL OF CELL SCIENCE

Fendiline Inhibits K-Ras Plasma Membrane Localization and Blocks K-Ras Signal Transmission

(2012) D. van der Hoeven et al.   MOLECULAR AND CELLULAR BIOLOGY

Phosphatidylserine dynamics in cellular membranes

(2012) Jason G. Kay et al.   MOLECULAR BIOLOGY OF THE CELL

PI4P and PI(4,5)P2 Are Essential But Independent Lipid Determinants of Membrane Identity

(2012) G. R. V. Hammond et al.   SCIENCE

A CC-SAM, for Coiled Coil-Sterile   Motif, Domain Targets the Scaffold KSR-1 to Specific Sites in the Plasma Membrane

(2012) D. Koveal et al.   Science Signaling

PAQR10 and PAQR11 mediate Ras signaling in the Golgi apparatus

(2011) Ting Jin et al.   CELL RESEARCH

PI3K/Akt signaling requires spatial compartmentalization in plasma membrane microdomains

(2011) X. Gao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Demonstration of Angiotensin II-induced Ras Activation in thetrans-Golgi Network and Endoplasmic Reticulum Using Bioluminescence Resonance Energy Transfer-based Biosensors

(2010) András Balla et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Acute manipulation of Golgi phosphoinositides to assess their importance in cellular trafficking and signaling

(2010) Z. Szentpetery et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ras membrane orientation and nanodomain localization generate isoform diversity

(2010) D. Abankwa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure and Dynamics of the Myristoyl Lipid Modification of Src Peptides Determined by 2H Solid-State NMR Spectroscopy

(2009) Holger A. Scheidt et al.   BIOPHYSICAL JOURNAL

A distinct pool of phosphatidylinositol 4,5-bisphosphate in caveolae revealed by a nanoscale labeling technique

(2009) A. Fujita et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Compartmentalization of Phosphatidylinositol 4,5-Bisphosphate Signaling Evidenced Using Targeted Phosphatases

(2008) Corey M. Johnson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mutational optimization of the coelenterazine-dependent luciferase from Renilla

(2008) Jongchan Woo et al.   Plant Methods

Membrane Phosphatidylserine Regulates Surface Charge and Protein Localization

(2008) T. Yeung et al.   SCIENCE