IL-1β-induced and p38MAPK-dependent activation of the mitogen-activated protein kinase-activated protein kinase 2 (MK2) in hepatocytes: Signal transduction with robust and concentration-independent signal amplification

MAPKAP kinase 2 regulates IL-10 expression and prevents formation of intrahepatic myeloid cell aggregates during cytomegalovirus infections

(2016) Christian Ehlting et al.   JOURNAL OF HEPATOLOGY

Oncostatin M regulates SOCS3 mRNA stability via the MEK–ERK1/2-pathway independent of p38MAPK/MK2

(2015) Christian Ehlting et al.   CELLULAR SIGNALLING

Lessons Learned from Quantitative Dynamical Modeling in Systems Biology

(2013) Andreas Raue et al.   PLoS One

Physiological mechanisms of signal termination in biological systems

(2012) E. Ligeti et al.   Acta Physiologica

p38 mitogen-activated protein kinase (p38 MAPK)-mediated autoimmunity: Lessons to learn from ANCA vasculitis and pemphigus vulgaris

(2012) Athanasios Mavropoulos et al.   AUTOIMMUNITY REVIEWS

New Therapeutic Targets in Cardiology

(2012) Eva Denise Martin et al.   CIRCULATION

Cellular ERK Phospho-Form Profiles with Conserved Preference for a Switch-Like Pattern

(2012) Bettina Hahn et al.   JOURNAL OF PROTEOME RESEARCH

Hepatic acute phase proteins – Regulation by IL-6- and IL-1-type cytokines involving STAT3 and its crosstalk with NF-κB-dependent signaling

(2011) Johannes G. Bode et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

The role of p38 mitogen-activated protein kinase in the pathogenesis of inflammatory bowel disease

(2011) Ya Jing FENG et al.   Journal of Digestive Diseases

Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases

(2011) M. Cargnello et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Mechanisms and functions of p38 MAPK signalling

(2010) Ana Cuadrado et al.   BIOCHEMICAL JOURNAL

Pathological roles of MAPK signaling pathways in human diseases

(2010) Eun Kyung Kim et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Two additive mechanisms impair the differentiation of 'substrate-selective' p38 inhibitors from classical p38 inhibitors in vitro

(2010) Bart S Hendriks et al.   BMC Systems Biology

Inactivation of p38 MAPK during liver regeneration

(2010) Jean S. Campbell et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Loss of p38  MAPK induces pleiotropic mitotic defects and massive cell death

(2010) A. Kukkonen-Macchi et al.   JOURNAL OF CELL SCIENCE

Cross-regulation of cytokine signalling: pro-inflammatory cytokines restrict IL-6 signalling through receptor internalisation and degradation

(2010) Simone Radtke et al.   JOURNAL OF CELL SCIENCE

Elevated GM-CSF and IL-1β levels compromise the ability of p38 MAPK inhibitors to modulate TNFα levels in the human monocytic/macrophage U937 cell line

(2010) Christopher W. Espelin et al.   Molecular BioSystems

Structural and practical identifiability analysis of partially observed dynamical models by exploiting the profile likelihood

(2009) A. Raue et al.   BIOINFORMATICS

Signal amplification in biological and electrical engineering systems

(2009) Vladimir Grubelnik et al.   BIOPHYSICAL CHEMISTRY

Targeting innate immunity protein kinase signalling in inflammation

(2009) Matthias Gaestel et al.   NATURE REVIEWS DRUG DISCOVERY

Analysis of Mechanistic Pathway Models in Drug Discovery: p38 Pathway

(2008) B.S. Hendriks et al.   BIOTECHNOLOGY PROGRESS