Post-transcriptional regulation of ERBB2 by miR26a/b and HuR confers resistance to tamoxifen in estrogen receptor-positive breast cancer cells

Alternative Polyadenylation: Another Foe in Cancer

(2016) A. E. Erson-Bensan et al.   MOLECULAR CANCER RESEARCH

Current Evidence and Future Perspectives on HuR and Breast Cancer Development, Prognosis, and Treatment

(2016) Ioly Kotta-Loizou et al.   NEOPLASIA

The Role of MicroRNAs as Predictors of Response to Tamoxifen Treatment in Breast Cancer Patients

(2015) Nina Egeland et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

HOXB7 Is an ER  Cofactor in the Activation of HER2 and Multiple ER Target Genes Leading to Endocrine Resistance

(2015) K. Jin et al.   Cancer Discovery

MicroRNA-320a sensitizes tamoxifen-resistant breast cancer cells to tamoxifen by targeting ARPP-19 and ERRγ*

(2015) Mingrong Lü et al.   Scientific Reports

CFIm25 links alternative polyadenylation to glioblastoma tumour suppression

(2014) Chioniso P. Masamha et al.   NATURE

Dynamic analyses of alternative polyadenylation from RNA-seq reveal a 3′-UTR landscape across seven tumour types

(2014) Zheng Xia et al.   Nature Communications

Post-Transcriptional Controls by Ribonucleoprotein Complexes in the Acquisition of Drug Resistance

(2013) Hoin Kang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

miR-29a inhibition normalizes HuR over-expression and aberrant AU-rich mRNA stability in invasive cancer

(2013) Wijdan Al-Ahmadi et al.   JOURNAL OF PATHOLOGY

Alternative cleavage and polyadenylation: extent, regulation and function

(2013) Ran Elkon et al.   NATURE REVIEWS GENETICS

miR-195 competes with HuR to modulate stim1 mRNA stability and regulate cell migration

(2013) Ran Zhuang et al.   NUCLEIC ACIDS RESEARCH

The Poly(A)-Binding Protein Nuclear 1 Suppresses Alternative Cleavage and Polyadenylation Sites

(2012) Mathias Jenal et al.   CELL

High miR-26a and low CDC2 levels associate with decreased EZH2 expression and with favorable outcome on tamoxifen in metastatic breast cancer

(2011) M. P. H. M. Jansen et al.   BREAST CANCER RESEARCH AND TREATMENT

miR-198 inhibits migration and invasion of hepatocellular carcinoma cells by targeting the HGF/c-MET pathway

(2011) Sheng Tan et al.   FEBS LETTERS

MicroRNA-26b is underexpressed in human breast cancer and induces cell apoptosis by targeting SLC7A11

(2011) Xiao-Xiao Liu et al.   FEBS LETTERS

Ending the message: poly(A) signals then and now

(2011) N. J. Proudfoot   GENES & DEVELOPMENT

The RNA-binding Protein HuR Opposes the Repression ofERBB-2Gene Expression by MicroRNA miR-331-3p in Prostate Cancer Cells

(2011) Michael R. Epis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Competitive Regulation of Nucleolin Expression by HuR and miR-494

(2011) K. Tominaga et al.   MOLECULAR AND CELLULAR BIOLOGY

Mechanisms and Consequences of Alternative Polyadenylation

(2011) Dafne Campigli Di Giammartino et al.   MOLECULAR CELL

Neuron-specific ELAV/Hu proteins suppress HuR mRNA during neuronal differentiation by alternative polyadenylation

(2011) Kyle D. Mansfield et al.   NUCLEIC ACIDS RESEARCH

Hepato-specific microRNA-122 facilitates accumulation of newly synthesized miRNA through regulating PRKRA

(2011) Shuai Li et al.   NUCLEIC ACIDS RESEARCH

RNA-binding protein HuR autoregulates its expression by promoting alternative polyadenylation site usage

(2011) Weijun Dai et al.   NUCLEIC ACIDS RESEARCH

Mechanisms of Endocrine Resistance in Breast Cancer

(2010) C. Kent Osborne et al.   Annual Review of Medicine

Cytoplasmic accumulation of the RNA binding protein HuR is central to tamoxifen resistance in estrogen receptor positive breast cancer cells

(2010) Christine Hostetter et al.   CANCER BIOLOGY & THERAPY

Molecular mechanisms of eukaryotic pre-mRNA 3′ end processing regulation

(2010) Stefania Millevoi et al.   NUCLEIC ACIDS RESEARCH

MicroRNA-125a represses cell growth by targeting HuR in breast cancer

(2010) Xun Guo et al.   RNA Biology

Therapeutic MicroRNA Strategies in Human Cancer

(2009) Chunsheng Li et al.   AAPS Journal

Widespread Estrogen-Dependent Repression of microRNAs Involved in Breast Tumor Cell Growth

(2009) G. Maillot et al.   CANCER RESEARCH

Widespread Shortening of 3′UTRs by Alternative Cleavage and Polyadenylation Activates Oncogenes in Cancer Cells

(2009) Christine Mayr et al.   CELL

Alternative polyadenylation variants of the RNA binding protein, HuR: abundance, role of AU-rich elements and auto-Regulation

(2009) Wijdan Al-Ahmadi et al.   NUCLEIC ACIDS RESEARCH

Estradiol-regulated microRNAs control estradiol response in breast cancer cells

(2009) Poornima Bhat-Nakshatri et al.   NUCLEIC ACIDS RESEARCH

Timing is everything: Order of administration of 5-aza 2′ deoxycytidine, trichostatin A and tamoxifen changes estrogen receptor mRNA expression and cell sensitivity

(2008) Christine L. Hostetter et al.   CANCER LETTERS

Crosstalk between the Estrogen Receptor and the HER Tyrosine Kinase Receptor Family: Molecular Mechanism and Clinical Implications for Endocrine Therapy Resistance

(2008) Grazia Arpino et al.   ENDOCRINE REVIEWS

MicroRNA-26a Targets the Histone MethyltransferaseEnhancer of Zeste homolog 2during Myogenesis

(2008) Chung Fai Wong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA-221/222 Confers Tamoxifen Resistance in Breast Cancer by Targeting p27Kip1

(2008) Tyler E. Miller et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Destabilization of ERBB2 Transcripts by Targeting 3' Untranslated Region Messenger RNA Associated HuR and Histone Deacetylase-6

(2008) G. K. Scott et al.   MOLECULAR CANCER RESEARCH

Regulation of ERBB2 by oestrogen receptor–PAX2 determines response to tamoxifen

(2008) Antoni Hurtado et al.   NATURE

Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?

(2008) Witold Filipowicz et al.   NATURE REVIEWS GENETICS