Cell cycle-dependent degradation of the methyltransferase SETD3 attenuates cell proliferation and liver tumorigenesis

SETD6 is a negative regulator of oxidative stress response

(2016) Ayelet Chen et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

PAK4 Methylation by SETD6 Promotes the Activation of the Wnt/β-Catenin Pathway

(2016) Zlata Vershinin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulating Fbw7 on the road to cancer

(2016) Wenshan Xu et al.   SEMINARS IN CANCER BIOLOGY

Chromatin associated SETD3 negatively regulates VEGF expression

(2016) Ofir Cohn et al.   Scientific Reports

A fluorescent bimolecular complementation screen reveals MAF1, RNF7 and SETD3 as PCNA-associated proteins in human cells

(2015) Simon E Cooper et al.   CELL CYCLE

SCFβ-TRCP promotes cell growth by targeting PR-Set7/Set8 for degradation

(2015) Zhiwei Wang et al.   Nature Communications

Tumor Suppression by the Fbw7 Ubiquitin Ligase: Mechanisms and Opportunities

(2014) Ryan J. Davis et al.   CANCER CELL

In multiple myeloma, 14q32 translocations are nonrandom chromosomal fusions driving high expression levels of the respective partner genes

(2014) Erming Tian et al.   GENES CHROMOSOMES & CANCER

Isoform-Specific SCFFbw7Ubiquitination Mediates Differential Regulation of PGC-1α

(2014) Julie S. Trausch-Azar et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Histone core modifications regulating nucleosome structure and dynamics

(2014) Peter Tessarz et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Histone Mark H3K36me3 Regulates Human DNA Mismatch Repair through Its Interaction with MutSα

(2013) Feng Li et al.   CELL

FBW7 regulates endothelial functions by targeting KLF2 for ubiquitination and degradation

(2013) Rui Wang et al.   CELL RESEARCH

SETD6 monomethylates H2AZ on lysine 7 and is required for the maintenance of embryonic stem cell self-renewal

(2013) Olivier Binda et al.   Epigenetics

The role of a newly identified SET domain-containing protein, SETD3, in oncogenesis

(2013) Z. Chen et al.   HAEMATOLOGICA

Parkin-Dependent Degradation of the F-Box Protein Fbw7  Promotes Neuronal Survival in Response to Oxidative Stress by Stabilizing Mcl-1

(2013) S. Ekholm-Reed et al.   MOLECULAR AND CELLULAR BIOLOGY

Mechanisms and function of substrate recruitment by F-box proteins

(2013) Jeffrey R. Skaar et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

SET for life: biochemical activities and biological functions of SET domain-containing proteins

(2013) Hans-Martin Herz et al.   TRENDS IN BIOCHEMICAL SCIENCES

PR-Set7 and H4K20me1: at the crossroads of genome integrity, cell cycle, chromosome condensation, and transcription

(2012) D. B. Beck et al.   GENES & DEVELOPMENT

DNA Replication Origin Function Is Promoted by H3K4 Di-methylation in Saccharomyces cerevisiae

(2012) L. F. Rizzardi et al.   GENETICS

Inflammasomes in carcinogenesis and anticancer immune responses

(2012) Laurence Zitvogel et al.   NATURE IMMUNOLOGY

Characterization of a Novel Histone H3K36 Methyltransferase setd3 in Zebrafish

(2011) Dong-Wook KIM et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

SET8 plays a role in controlling G1/S transition by blocking lysine acetylation in histone through binding to H4 N-terminal tail

(2011) Yinliang Yin et al.   CELL CYCLE

Nucleosomes in the neighborhood

(2011) Elizabeth Suzanne Dorn et al.   Epigenetics

Histone Methyltransferase SETD3 Regulates Muscle Differentiation

(2011) Gwang Hyeon Eom et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SCFFBW7 regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction

(2011) Hiroyuki Inuzuka et al.   NATURE

Dynamic regulation of the PR-Set7 histone methyltransferase is required for normal cell cycle progression

(2010) S. Wu et al.   GENES & DEVELOPMENT

Regulation of the Histone H4 Monomethylase PR-Set7 by CRL4Cdt2-Mediated PCNA-Dependent Degradation during DNA Damage

(2010) Hisanobu Oda et al.   MOLECULAR CELL

CRL4Cdt2-Mediated Destruction of the Histone Methyltransferase Set8 Prevents Premature Chromatin Compaction in S Phase

(2010) Richard C. Centore et al.   MOLECULAR CELL

CRL4Cdt2 Regulates Cell Proliferation and Histone Gene Expression by Targeting PR-Set7/Set8 for Degradation

(2010) Tarek Abbas et al.   MOLECULAR CELL

Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling

(2010) Dan Levy et al.   NATURE IMMUNOLOGY

The ubiquitous nature of cancer: the role of the SCFFbw7 complex in development and transformation

(2010) K M Crusio et al.   ONCOGENE

Catalytic Function of the PR-Set7 Histone H4 Lysine 20 Monomethyltransferase Is Essential for Mitotic Entry and Genomic Stability

(2008) Sabrina I. Houston et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Plk1- and β-TrCP–dependent degradation of Bora controls mitotic progression

(2008) Akiko Seki et al.   JOURNAL OF CELL BIOLOGY

Cyclin-dependent kinases and cell-cycle transitions: does one fit all?

(2008) Helfrid Hochegger et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY